Diagnostic Insights for Skin Melanoma

Dear Colleagues,

According to the Global Cancer Observatory, which is provided by the International Agency for Research on Cancer of the World Health Organization, skin melanoma ranked as the 17th most prevalent form of cancer in 2022, with 331,722 new cases (both sexes, all ages); of these, 146,321 cases were reported in Europe (44.1%), 112,807 in Northern America (34.0%), 25,003 in Asia (7.5%), 20,291 in Latin American and the Caribbean (6.1%), 19,823 in Oceania (6.0%), and 7477 in Africa (2.3%). In addition, it places 22nd in terms of mortality, with 58,667 deaths (both sexes, all ages); of these, 26,180 were in Europe (44.6%). Melanoma of the skin therefore represents a dangerous cancer that exerts a significant impact in developed countries, where technology reigns supreme. Nevertheless, the diagnosis of skin melanoma can only be achieved with certainty via the performance of a common tissue biopsy and histopathological examination, the same as that performed in underdeveloped or developing countries. This Special Issue provides a full overview of the diagnostics of cutaneous melanoma from both a histological and clinical perspective, including immunohistochemistry, dermatoscopy, reflectance confocal microscopy, and the application of modern artificial intelligence tools to images; these techniques have recently become extremely popular in developed countries, with clinico-pathological correlations.

Dr. Luca Roncati
Guest Editor

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