Advances in the Diagnosis of Oral and Maxillofacial Disease: 2nd Edition

A special issue of Diagnostics (ISSN 2075-4418). This special issue belongs to the section "Clinical Diagnosis and Prognosis".

Deadline for manuscript submissions: 30 June 2025 | Viewed by 754

Special Issue Editor

Special Issue Information

Dear Colleagues,

We want to thank all researchers who contributed high-quality manuscripts to the Special Issue “Advances in the Diagnosis of Oral and Maxillofacial Disease”. The positive feedback and general interest we received encouraged us to launch a second volume, focusing on the diagnosis of oral and maxillofacial diseases.

The forthcoming Special Issue of Diagnostics, titled "Advances in the Diagnosis of Oral and Maxillofacial Disease: Volume 2", will present cutting-edge developments in the field of diagnosing conditions affecting the mouth, jaw, and related structures. This comprehensive collection of articles will delve into the latest advancements in diagnostic techniques, technologies, and methodologies, aiming to enhance the early detection, accurate diagnosis, and effective management of oral and maxillofacial diseases.

The contributions within this edition will explore various aspects of diagnostic modalities, including advanced radiology techniques such as cone beam computed tomography (CBCT) and magnetic resonance imaging (MRI), which offer detailed anatomical information for precise diagnosis and treatment planning. Additionally, the articles included will discuss the application of optical imaging and diagnostic tools, providing insights into non-invasive methods for detecting early signs of disease and monitoring treatment responses.

Pathology and biopsy techniques will also be discussed, highlighting the role of histopathological analysis in confirming diagnoses and guiding therapeutic interventions. Furthermore, the integration of molecular diagnostics and medical screening protocols will be explored, showcasing the potential of genetic and molecular markers in early disease detection and personalized treatment approaches.

This Special Issue will also address prognostic assessments and the identification of biomarkers associated with disease progression and treatment response. By synthesizing the latest research findings and clinical insights across these diverse diagnostic modalities, this edition of Diagnostics will serve as a valuable resource for clinicians, researchers, and healthcare professionals involved in the diagnosis and management of oral and maxillofacial diseases. Ultimately, these advancements will contribute to improved patient care, treatment outcomes, and quality of life.

Dr. Luís Eduardo Almeida
Guest Editor

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Keywords

  • maxillofacial disease
  • oral disease
  • biomarkers
  • prognosis
  • periodontal disease
  • machine learning
  • MRI
  • CBCT

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Published Papers (1 paper)

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Research

16 pages, 924 KiB  
Article
Age- and Gender-Based Tongue Volume Variations on Asymptomatic Patients: A Simplified Approach to Form Baseline Data for Obstructive Sleep Apnea
by Betül Tiryaki Baştuğ
Diagnostics 2025, 15(3), 322; https://doi.org/10.3390/diagnostics15030322 - 30 Jan 2025
Viewed by 572
Abstract
Background: Tongue anatomy plays a critical role in airway-related disorders such as obstructive sleep apnea (OSA). Understanding variations in tongue volume across age and gender is essential for refining diagnostic and therapeutic strategies. This study aims to establish baseline data for tongue volume [...] Read more.
Background: Tongue anatomy plays a critical role in airway-related disorders such as obstructive sleep apnea (OSA). Understanding variations in tongue volume across age and gender is essential for refining diagnostic and therapeutic strategies. This study aims to establish baseline data for tongue volume using a simplified geometric approach, addressing the gap in large-scale anatomical assessments, specifically in asymptomatic patients without clinical indications of OSA. Materials and Methods: This retrospective cross-sectional study included 120 asymptomatic patients aged 18–75 years, stratified into three age groups (18–40, 41–60, 61+). Tongue volume was estimated using anterior–posterior length, width, and height measurements from neck CT scans, applying a geometric approximation formula. Statistical analysis, including ANOVA and post hoc tests, was used to evaluate differences across age groups and between genders. Regression analysis examined the influence of age and gender on tongue volume. Results: Tongue volume showed a significant decline with advancing age (p < 0.05), with the 61+ age group exhibiting the smallest volumes. Gender differences were pronounced, with males consistently having larger volumes than females (p < 0.05). Post hoc analyses confirmed significant differences between age groups, and regression analysis indicated that gender was a stronger predictor of tongue volume than age. Conclusions: This study highlights the impact of age and gender on tongue volume, emphasizing the need for demographic-specific approaches in the evaluation and management of airway-related conditions. The simplified measurement method offers a practical solution for large-scale studies, providing baseline data for future research and clinical applications. These findings pave the way for personalized diagnostic thresholds and therapeutic strategies in conditions like OSA. Full article
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