Neuronal Development and Disease: From Molecular Bases to Neurological Disorders
A special issue of Cells (ISSN 2073-4409). This special issue belongs to the section "Cells of the Nervous System".
Deadline for manuscript submissions: 31 July 2025 | Viewed by 635
Special Issue Editor
2. Center for Neuroscience and Cell Biology, University of Coimbra, Coimbra, Portugal
Interests: synapse formation; local mRNA translation; local protein synthesis; neuronal cell death; excitotoxicity; neurodevelopmental disorders; microfluidics
Special Issue Information
Dear Colleague,
The intricate processes underlying neuronal development are critical in the establishment of a functional nervous system. From early neurogenesis to synaptic formation, these processes are finely tuned, allowing for the proper wiring and functioning of the brain. However, disruptions in these developmental pathways can lead to a wide array of neurological disorders, ranging from developmental disorders in childhood to neurodegenerative diseases in adulthood. Understanding the molecular, genetic, and cellular mechanisms that govern neuronal development and how these mechanisms are altered in disease is crucial in advancing therapeutic strategies.
This Special Issue on neuronal development and disease will bring together cutting-edge research that explores the intersection of these two key domains. Contributions from diverse areas, including stem cell biology, neurogenesis, synaptic plasticity, and neuroinflammation, will provide new insights into the developmental origins of neurological diseases. By including studies on topics spanning model organisms, advanced imaging techniques, and innovative therapeutic approaches, we aim to highlight the complexity of neuronal development and its disruption in disease contexts.
For this Special Issue, we welcome submissions of original research articles and reviews focusing on the mechanisms that explain the regular functioning of the nervous system, as wells as its functioning in disease states, at the cellular, system, or whole-organism level.
Dr. Ramiro Almeida
Guest Editor
Manuscript Submission Information
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Keywords
- neuronal development
- neurological disorders
- neurogenesis
- neuroinflammation
- synaptic plasticity
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