Advances in Understanding Skeletal Muscle Metabolism and Regeneration: From Mechanisms to Therapeutics
A special issue of Cells (ISSN 2073-4409). This special issue belongs to the section "Tissues and Organs".
Deadline for manuscript submissions: 31 July 2025 | Viewed by 165
Special Issue Editor
Interests: aging; stroke; skeletal muscle atrophy, growth, regeneration, and metabolism; genomics; proteomics; metabolomics; bioinformatics
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Skeletal muscle, which accounts for 40% of total body weight, has diverse functions, including maintaining body posture and producing mobility and movement. Skeletal muscle is also essential for maintaining whole-body energy homeostasis, as it is involved in glucose and fatty acid metabolisms. Muscle tissue deteriorates with aging both quantitatively and qualitatively, which increases the risks of falls, osteoporosis, and metabolic diseases. Thus, maintaining muscle mass is important for a healthier life. Moreover, muscle mass can significantly impact the effects of various treatments, particularly in scenarios like cachexia, where a higher muscle mass often leads to better tolerance of treatment side effects and improved overall outcomes. In contrast, significant muscle loss (muscle wasting) can indicate poorer prognosis and increased toxicity due to reduced ability to withstand treatment stress; essentially, more muscle mass generally means better ability to cope with treatment demands. Therefore, maintaining muscle mass is important for whole-body metabolic homeostasis. Similarly, proper muscle regeneration is a key to maintaining muscle mass because it has been shown that muscle regeneration is significantly reduced in many disease and disorder conditions. We are looking for any kind of research manuscript that shows the data related to muscle metabolisms and regeneration.
Dr. Junaith S. Mohamed
Guest Editor
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Keywords
- skeletal muscle
- satellite cells
- myoblast
- myogenesis
- regeneration
- mitochondria
- metabolism
- sarcopenia
- cachexia
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