Establishment and Characterization of Novel Patient-Derived Cancer Model
A special issue of Cells (ISSN 2073-4409).
Deadline for manuscript submissions: 31 July 2025 | Viewed by 137
Special Issue Editors
Interests: patient-derived cancer model; rare cancer research; sarcoma; expanded indication; biobank; viral carcinogenesis; transcriptomics; exosome/miRNA; tissue culture; primary culture
Special Issues, Collections and Topics in MDPI journals
Interests: rare cancer research; sarcoma; proteogenomics; applications of patient-derived cancer model
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Patient-derived cancer models are transformative tools that have advanced our understanding of cancer biology and catalyzed breakthroughs in personalized medicine. These models support functional investigations of novel genes and proteins, provide platforms for the high-throughput screening of anti-cancer agents, and illuminate the molecular underpinnings of tumor progression. Despite these achievements, significant gaps remain, particularly for rare and underrepresented cancer types, underscoring the need to expand and share these resources within the research community.
This Special Issue, titled "Establishment and Characterization of Novel Patient-Derived Cancer Models", aims to spotlight the latest advancements in this critical area. We welcome original research articles and reviews addressing the development and characterization of novel cancer models derived from patient samples, as well as innovative methodologies for model establishment and applications in functional genomics and drug discovery. Submissions may also explore the integration of patient-derived models with emerging technologies to tackle unresolved questions in cancer research. Moreover, novel cancer models that advance our understanding of etiology and disease progression, as well as support precision medicine, are valuable topics of discussion across various cancer types. By gathering these cutting-edge contributions, we seek to foster collaboration and knowledge exchange, ultimately broadening the utility of patient-derived models in both basic and translational cancer research. We look forward to your submissions and insights.
Dr. Yuki Yoshimatsu
Dr. Tadashi Kondo
Guest Editors
Manuscript Submission Information
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Keywords
- patient-derived cancer model
- primary tissue culture
- cell line
- spheroid
- organoid
- xenograft
- PDX
- organ-on-a-chip
- comparative oncology
- precision medicine
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