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Cancers publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Prevention, Early Detection, and Surgical Oncology in Hepatocellular Carcinoma, Pancreatic Cancer, and Gastrointestinal Cancer

edited by

Mingyao Chen

and

Kuang-Chun Hu

submission deadline 30 Oct 2025 | 1 articles | Viewed by 952 | Submission Open

Keywords: early image detection in cancer; biomarker of cancer; surgical treatment; gastrointestinal cancer

(This special issue belongs to the Section Cancer Causes, Screening and Diagnosis)

Treg Cell Immunotherapy in Cancer

edited by

Maria Velegraki

submission deadline 30 Oct 2025 | Viewed by 788 | Submission Open

Keywords: treg cells; cancer immunotherapy; immune evasion; antitumor immune responses; targeting therapeutic interventions

(This special issue belongs to the Section Cancer Therapy)

Cancer Immunotherapy as Part of Precision Clinical Medicine

edited by

Peter Lang

and

Christo Kole

submission deadline 30 Oct 2025 | Viewed by 191 | Submission Open

Keywords: cancer; immunotherapy; tumor microenvironment; molecular biology and genetics

(This special issue belongs to the Section Cancer Immunology and Immunotherapy)

Management of Pancreatic Cancer

edited by

Traian Dumitrascu

submission deadline 31 Oct 2025 | 14 articles | Viewed by 23554 | Submission Open

Keywords: pancreatic cancer; adenocarcinoma; neuroendocrine carcinomas; molecular and pathological aspects; diagnosis; medical treatment; palliative therapy

(This special issue belongs to the Section Cancer Therapy)

Novel Prognostic Biomarkers in Human Cancers: From Discovery to Application

edited by

Zakaria Y. Abd Elmageed

submission deadline 31 Oct 2025 | 4 articles | Viewed by 9442 | Submission Open

Keywords: tumor biomarkers; investigational markers; prognosis; biochemical relapse; overall survival; clinical trials; advancement in biomarker discovery; bioinformatics and marker discovery; AI and biomarker discovery

(This special issue belongs to the Section Cancer Biomarkers)

Neurofibromatosis

edited by Rianne Oostenbrink,

Ignaci Blanco

and Enrico Opocher

submission deadline 31 Oct 2025 | 8 articles | Viewed by 9391 | Submission Open

Keywords: neurofibromatosis; schwannomatosis; tumor; longitudinal history; treatment; biomarker; outcomes

(This special issue belongs to the Section Cancer Therapy)

Molecular Mechanisms in Head and Neck Cancer

edited by Désirée Gül, Jan Hagemann and

Roland Hans Stauber

submission deadline 31 Oct 2025 | 5 articles | Viewed by 9165 | Submission Open

Keywords: head and neck cancer; translational research; molecular pathways; cellular signaling; biomarkers; liquid biopsies; transcriptome; proteome; survival

(This special issue belongs to the Section Molecular Cancer Biology)

Treatment Outcomes in Older Adults with Cancer

edited by

Mackenzi Pergolotti

submission deadline 31 Oct 2025 | 6 articles | Viewed by 8441 | Submission Open

Keywords: older adults with cancer; geriatric oncology; geriatric assessment; supportive care; palliative care; cancer rehabilitation; nutrition; physical activity; functional status; survivorship

(This special issue belongs to the Section Cancer Therapy)

Clinical Research Advances in Endometrial Carcinoma

edited by Salvatore Lopez

submission deadline 31 Oct 2025 | 5 articles | Viewed by 8364 | Submission Open

Keywords: endometrial cancer; uterine serous carcinoma; immunotherapy; MMRd; POLE; endometrioid carcinoma; target therapies; surgery; preclinical research

(This special issue belongs to the Section Clinical Research of Cancer)

Advances in TNBC: New Markers for Innovative Treatments

edited by

Pia Giovannelli

submission deadline 31 Oct 2025 | 3 articles | Viewed by 7835 | Submission Open

Keywords: TNBC treatment; TNBC target; signaling pathways in TNBC; epigenetic modifications in TNBC; immunotherapy; personalized medicine

(This special issue belongs to the Section Cancer Therapy)

Advances and Challenges in the Diagnosis and Treatment of Urological Malignancies (2nd Edition)

edited by

Bartosz Małkiewicz

Jakub Dobruch

and

Łukasz Nowak

submission deadline 31 Oct 2025 | 6 articles | Viewed by 6923 | Submission Open

Keywords: prostate cancer; bladder cancer; upper urinary tract tumors; kidney cancer; testicular tumors; molecular markers; lymph node metastasis; diagnosis; radical treatment; systemic treatment

(This special issue belongs to the Section Cancer Causes, Screening and Diagnosis)

Targeted Therapies for EGFR in Non-Small Cell Lung Cancer

edited by

Federico Pio Fabrizio

submission deadline 31 Oct 2025 | 3 articles | Viewed by 6272 | Submission Open

Keywords: EGFR; non-small cell lung cancer; molecular mechanisms; targeted therapies; resistance mechanisms

(This special issue belongs to the Section Cancer Therapy)

Advances in Uveal Melanoma

edited by

Takami Sato

and

Mizue Terai

submission deadline 31 Oct 2025 | 4 articles | Viewed by 6150 | Submission Open

Keywords: uveal melanoma; eye cancer; liver metastasis; Gα q/11 mutations; BAP1; SF3B1; PRAME; dormancy; liver-directed treatment; T-cell engager

(This special issue belongs to the Section Molecular Cancer Biology)

A New Era in the Treatment of Early-Stage Non-Small Cell Lung Cancer

edited by

Tsutani Yasuhiro

submission deadline 31 Oct 2025 | 3 articles | Viewed by 5548 | Submission Open

Keywords: minimally invasive surgery; video-assisted thoracic surgery; robotic-assisted thoracic surgery; sublobar resection; segmentectomy; neoadjuvant therapy; adjuvant therapy; immunotherapy; targeted therapy

(This special issue belongs to the Section Cancer Therapy)

The Role of Genes in Prostate Cancer

edited by Olivier Cussenot

submission deadline 31 Oct 2025 | 3 articles | Viewed by 4619 | Submission Open

Keywords: prostate cancer; genes; microenvironment

(This special issue belongs to the Section Tumor Microenvironment)

Combination Therapies for Brain Tumors

edited by Jason H. Huang and Ekokobe Fonkem

submission deadline 31 Oct 2025 | 5 articles | Viewed by 4227 | Submission Open

Keywords: novel diagnostics; therapies; glioblastoma; meningioma; astrocytoma

(This special issue belongs to the Section Cancer Therapy)

Gastrointestinal Cancer Surgery

edited by Florian Primavesi and

Daniel Neureiter

submission deadline 31 Oct 2025 | 4 articles | Viewed by 4013 | Submission Open

Keywords: gastrointestinal cancer surgery; precision surgery; personalized medicine; robotics; pathology; colorectal cancer; stomach cancer; pancreatic cancer; hepatocellular cancer; biliary tract cancer

(This special issue belongs to the Section Cancer Therapy)

Neo-Adjuvant Treatment of Breast Cancer

edited by Raphael Catane

submission deadline 31 Oct 2025 | 2 articles | Viewed by 3403 | Submission Open

Keywords: neo-adjuvant; breast cancer; chemotherapy; hormonal therapy; immunotherapy; breast cancer survival; breast cancer surgery; Norton– Simon hypothesis

(This special issue belongs to the Section Cancer Therapy)

Advancements in “Cancer Biomarkers” for 2025–2026

edited by

Maxim V. Berezovski

submission deadline 31 Oct 2025 | 4 articles | Viewed by 3253 | Submission Open

Keywords: RNA biomarkers; miRNA biomarkers; DNA biomarkers; cell-free DNA (cfDNA); protein biomarkers; metabolomic biomarkers; mutational biomarkers; circulating tumor cells (CTCs); tumor-derived extracellular vesicle (tEV) biomarkers; cellular biomarkers; imaging biomarkers; clinical biomarkers; biomarkers of drug response; biomarkers of genetic predisposition to cancer; epigenetic biomarkers; biomarkers of cancer outcomes; mass spectrometry; next-generation sequencing (NGS); flow cytometry; positron emission tomography (PET); computed tomography (CT); magnetic resonance imaging (MRI); X-rays; ultrasound; electrocardiography (ECG/EKG); endoscopy; biopsy; pulmonary function tests (PFTs); histopathology; cytopathology; immunohistochemistry (IHC); in situ hybridization (ISH); fluorescence in situ hybridization (FISH); liquid biopsy; electron microscopy; digital pathology and image analysis

(This special issue belongs to the Section Cancer Biomarkers)

Molecular Genetics, Signaling Pathways, and Therapeutic Strategies for Liver Cancer

edited by

Wai-Hung Ho Daniel

and Yuman Tsui

submission deadline 31 Oct 2025 | 3 articles | Viewed by 3209 | Submission Open

Keywords: liver cancer; NGS; single-cell sequencing; cancer genomics; cellular and molecular landscapes; tumor microenvironment; tumor heterogeneity; liver cancer stem cell; liquid biopsy; biomarkers

(This special issue belongs to the Section Molecular Cancer Biology)

Recent Advances in Diagnosis and Management of Colorectal Cancer

edited by Shing Wai Wong, Stephen Thompson and Zhen Hao Ang

submission deadline 31 Oct 2025 | 3 articles | Viewed by 2837 | Submission Open

Keywords: colorectal cancer; diagnosis; management; screening; surgery; radiotherapy; chemotherapy; immunotherapy; robotics; targeted therapy; prevention; prognosis

(This special issue belongs to the Section Clinical Research of Cancer)

The Roles of Deep Learning in Cancer Radiotherapy

edited by Zhen Tian

submission deadline 31 Oct 2025 | 2 articles | Viewed by 2551 | Submission Open

Keywords: radiotherapy; deep learning; artificial Intelligence; tumor detection; image segmentation; treatment planning; outcome prediction; radiomics

(This special issue belongs to the Section Cancer Informatics and Big Data)

Research Advances in Cancer Nanomedicine

edited by

Stefano Leporatti

submission deadline 31 Oct 2025 | 1 articles | Viewed by 2509 | Submission Open

Keywords: cancer; nanotechnology; nanomedicine; drug delivery; biosensors; lab-on-chip; nanomechanics; nano-immuno therapy; CAR-T nano-technology

(This special issue belongs to the Section Methods and Technologies Development)

Digital Pathology Systems Enabling the Quality of Cancer Patient Care

edited by Peter J. Schüffler

submission deadline 31 Oct 2025 | 2 articles | Viewed by 2318 | Submission Open

Keywords: digital pathology; computational pathology; artificial intelligence; multimodal AI; foundation models; quality control; quality assurance; medical image analysis; computer-aided diagnosis; integrated digital pathology

(This special issue belongs to the Section Cancer Pathophysiology)

Radiomics in Cancer Imaging: Theory and Applications in Solid Tumours

edited by

Francesco Bianconi

and

Barbara Palumbo

submission deadline 31 Oct 2025 | 2 articles | Viewed by 1776 | Submission Open

Keywords: radiomics for the diagnosis; prognostication and treatment planning of solid tumours; methods; translational research and clinical applications; conventional and deep learning radiomics; interpretability of radiomics features and prediction models; image processing (including acquisition; segmentation and feature extraction); imaging methods (including CT; MRI; PET; SPECT and US)

(This special issue belongs to the Section Cancer Causes, Screening and Diagnosis)

Diagnostic Biomarkers in Cancers Study

edited by Zejuan Li and

Xin Yi

submission deadline 31 Oct 2025 | 2 articles | Viewed by 1763 | Submission Open

Keywords: cancer; diagnostics; biomarker

(This special issue belongs to the Section Cancer Biomarkers)

Human Papillomavirus (HPV) and Related Cancer

edited by

Beata Biesaga

submission deadline 31 Oct 2025 | 1 articles | Viewed by 1071 | Submission Open

Keywords: HPV; carcinogenesis; methods of virus identification diagnostics; prognostification

(This special issue belongs to the Section Infectious Agents and Cancer)

News and How Much to Improve in Management of Soft Tissue Sarcomas

edited by Vicente Artigas-Raventós and

José Manuel Asencio

submission deadline 31 Oct 2025 | 1 articles | Viewed by 1006 | Submission Open

Keywords: soft tissue sarcomas; prevalent types; multidisciplinary board; reference centers; news diagnosis methods and treatments; implication of IA and 3D in sarcomas; implication of minimally aggressive surgical techniques

(This special issue belongs to the Section Cancer Therapy)

Advances in Pancreatoduodenectomy

edited by Chang Moo Kang and Jae Hoon Lee

submission deadline 31 Oct 2025 | 1 articles | Viewed by 933 | Submission Open

Keywords: surgical innovations and techniques in pancreatoduodenectomy; surgical anatomy to understand pancreatoduodenectomy; advances in preoperative imaging and planning; perioperative care and complications management; oncologic outcomes and long-term survival studies; multidisciplinary approaches to enhance patient outcomes; emerging technologies and their impact on surgical precision

(This special issue belongs to the Section Clinical Research of Cancer)

Prognosis and Treatment of Cutaneous Melanoma (2nd Edition)

edited by

Eduardo Nagore

submission deadline 31 Oct 2025 | 1 articles | Viewed by 819 | Submission Open

Keywords: prognosis; melanoma; adjuvant; germline; somatic; genetic; epigenetic; neoadjuvant

(This special issue belongs to the Section Cancer Therapy)

Advances in the Clinical Management of Genitourinary Tumors

edited by

Felix Busch

and Markus Graf

submission deadline 31 Oct 2025 | 1 articles | Viewed by 712 | Submission Open

Keywords: urogenital neoplasms; prostatic neoplasms; kidney neoplasms; ureteral neoplasms; urethral neoplasms; testicular neoplasms; urinary bladder neoplasms; disease management; artificial intelligence; precision medicine

(This special issue belongs to the Section Clinical Research of Cancer)

Advances in Skin Cancer Diagnostics and Therapy: Research and Clinical Studies (2nd Edition)

edited by Cristel Ruini

submission deadline 31 Oct 2025 | 1 articles | Viewed by 530 | Submission Open

Keywords: non-melanoma skin cancer; melanoma; actinic keratosis; field cancerisation; medical diagnostics; dermatology; dermoscopy; optical coherence tomography; in vivo confocal microscopy; ex vivo confocal microscopy; artificial intelligence

(This special issue belongs to the Section Cancer Therapy)

Advances in Targets for CAR T Therapy in Hematologic Malignancies

edited by

Ugo Testa

submission deadline 31 Oct 2025 | 1 articles | Viewed by 442 | Submission Open

Keywords: cancer immunotherapy; chimeric antigen receptor T-cell (CAR-T); leukemia; lymphoma; myeloma

(This special issue belongs to the Section Cancer Therapy)

Chemoprevention Advances in Cancer (2nd Edition)

edited by

Komal Raina

submission deadline 31 Oct 2025 | 1 articles | Viewed by 375 | Submission Open

Keywords: cancer prevention; chemoprevention; nutrition and cancer; bio-active food components; natural products; non-toxic anticancer agents; precision nutrition in cancer; tumor metabolomics; gut microbiome in cancer

(This special issue belongs to the Section Cancer Epidemiology and Prevention)

Cancer Screening and Primary Care

edited by Marievelisse Soto-Salgado

submission deadline 31 Oct 2025 | Viewed by 334 | Submission Open

Keywords: screening amenable cancers; screening; primary care; disparities in cancer care; cancer outcomes

(This special issue belongs to the Section Cancer Epidemiology and Prevention)

Cancer Inhibitory Receptors and Related Cancer Immunotherapy

edited by Keqiang Chen, Feng Zhu and Xin Li

submission deadline 31 Oct 2025 | Viewed by 222 | Submission Open

Keywords: cancer inhibitory receptors; ligands for inhibitor receptors; immune checkpoint inhibitors; cancer cells; immune cells; non-immune cells; inhibitor receptor pathways; immune checkpoint blockade therapy

(This special issue belongs to the Section Cancer Immunology and Immunotherapy)

The Role of Nutrients in Cancer Progression

edited by

Ikuko Kato

submission deadline 31 Oct 2025 | Viewed by 217 | Submission Open

Keywords: vitamins; phytochemicals; trace minerals; ketogenic diet; cancer recurrence; cancer metastasis; treatment response; radiotherapy; chemotherapy; immunotherapy

(This special issue belongs to the Section Cancer Pathophysiology)

Heme Metabolism in Oncogenesis and Tumor Microenvironment: Mechanisms and Emerging Therapeutic Strategies

edited by Rays H.Y. Jiang and Gloria C. Ferreira

submission deadline 31 Oct 2025 | Viewed by 195 | Submission Open

Keywords: heme metabolism; oncogenesis; tumor microenvironment; porphyrin biosynthesis; redox homeostasis; cancer metabolism; heme biosynthesis pathways; CRISPR screening; iron metabolism; therapeutic targeting of heme pathways

(This special issue belongs to the Section Tumor Microenvironment)

Epigenetic Regulators and Cancer Precision Therapies

edited by Biaoru Li

submission deadline 31 Oct 2025 | Viewed by 186 | Submission Open

Keywords: tumorigenesis; epigenetics; epigenomics; personalized therapy

(This special issue belongs to the Section Cancer Therapy)

Lung Cancer: Updates on Therapy and Prognostic Prediction

edited by Servet Bölükbas

submission deadline 31 Oct 2025 | Viewed by 182 | Submission Open

Keywords: lung cancer; targeted therapy; immunotherapy; prognostic prediction; precision medicine; biomarkers; artificial intelligence; next-generation sequencing; personalized treatment

(This special issue belongs to the Section Cancer Causes, Screening and Diagnosis)

Proton and Light Ion Therapy for Cancer

edited by Oliver Jäkel

submission deadline 31 Oct 2025 | Viewed by 159 | Submission Open

Keywords: novel beam delivery concepts; image guidance; adaptive therapy; in vivo monitoring; radiobiological studies with protons and light ions; clinical studies; outcome reports

(This special issue belongs to the Section Cancer Therapy)

Recent Updates and Future Perspectives of Anti-Cancer Agents

edited by

Santosh Kumar Singh

submission deadline 31 Oct 2025 | Viewed by 142 | Submission Open

Keywords: cancer; anti-cancer agents; targeted therapy; drug resistance; therapeutic agents; natural compounds; combination therapy; nanotherapy; translational therapy; immunotherapy

(This special issue belongs to the Section Cancer Drug Development)

Advances in Early Diagnosis and Minimally Invasive Management in Breast Cancer

edited by

Graziella Di Grezia

submission deadline 31 Oct 2025 | Viewed by 136 | Submission Open

Keywords: precision medicine; breast cancer prevention; cancer detection; early diagnosis; therapeutic strategies; artificial intelligence; image analysis; risk predictors

(This special issue belongs to the Section Methods and Technologies Development)

Innovations in Endocrine Cancer—Technology, Techniques and Therapy (Second Edition)

edited by

Emad H. Kandil

submission deadline 31 Oct 2025 | Viewed by 135 | Submission Open

Keywords: endocrine cancer; thyroid cancer; parathyroid; adrenals; melanoma; pancreas; neoplasms; minimally invasive surgeries

(This special issue belongs to the Section Methods and Technologies Development)

Pathology of Gynecological Cancers—Second Edition

edited by

Mohamed Desouki

submission deadline 31 Oct 2025 | Viewed by 129 | Submission Open

Keywords: endometrial cancer; ovarian cancer; vulvar cancer; cervical cancer; vaginal cancer

(This special issue belongs to the Section Cancer Pathophysiology)

The Role of Artificial Intelligence in Thyroid, Thoracic and Gastrointestinal Tumors: Transforming the Landscape of Diagnosis and Treatment

edited by

Michael I. Koukourakis

and

Athanasia Mitsala

submission deadline 31 Oct 2025 | Viewed by 122 | Submission Open

Keywords: artificial intelligence; thyroid cancer; thoracic cancer; gastrointestinal cancer; diagnosis; medical imaging; treatment; surgery

(This special issue belongs to the Section Cancer Causes, Screening and Diagnosis)

Osteosarcoma: Individualized Precision Treatment and Effective Drug Discovery

edited by

Margherita Cortini

submission deadline 31 Oct 2025 | Viewed by 89 | Submission Open

Keywords: osteosarcoma; bone cancer; tumor microenvironment; targeted therapies; precision medicine; 3D tumor models; drug screening

(This special issue belongs to the Section Cancer Drug Development)

Childhood Cancer in the Genomic Era: Experimental and Theoretical Approaches (2nd Edition)

edited by

George I. Lambrou

submission deadline 31 Oct 2025 | Viewed by 76 | Submission Open

Keywords: microarrays; NGS; mutation analysis; CNV; epigenetics; modeling; mathematical models; physical models

(This special issue belongs to the Section Molecular Cancer Biology)

New Strategies for the Treatment of Melanoma and Non-Melanoma Skin Cancer

edited by

Yoshihide Asano

and

Taku Fujimura

submission deadline 31 Oct 2025 | Viewed by 68 | Submission Open

Keywords: melanoma; non-melanoma skin cancer; immunotherapy; anti-PD-1 antibody; BRAF/MEK inhibitors; racial differences; prognosis

(This special issue belongs to the Section Cancer Therapy)

Immune Biomarkers and Checkpoint Inhibitors: Advancing Immunotherapy in Gynecologic Cancers

edited by Ting-Tai Yen and Eugene Patrick Toy

submission deadline 31 Oct 2025 | Viewed by 32 | Submission Open

Keywords: immune checkpoints; checkpoint inhibitors; PD-1/PD-L1 pathway; immune biomarkers; tumor microenvironment; immunosuppressive pathways; T-cell activation in solid tumors; gynecologic tumors

(This special issue belongs to the Section Cancer Immunology and Immunotherapy)

Displaying special issue 551-600 on page 12 of 22.

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