Molecular Mechanisms in Bone and Soft Tissue Sarcomas

Dear Colleagues,

Bone and soft tissue sarcomas are rare, but disproportionately lethal cancers. Despite having a common cell of origin, there are a multitude of subtypes characterized by a significant genetic heterogeneity. This tumor heterogeneity has limited treatment progress, as a “one size fits all” approach has demonstrated limited efficacy. While surgery and adjuvant therapies are typically considered the mainstay of treatment, evolving understanding of the molecular underpinnings of these tumors, is revolutionizing the care of these tumors.

This Special Issue aims to update the current knowledge and future implications of the molecular underpinnings of bone and soft tissue sarcomas in order to highlight the current understanding of these tumors on a molecular level and the promising therapeutic approaches in the treatment of these challenging disease entities. Continued research is needed to identify the current obstacles and explore novel solutions to help optimize patient care, with a focus on how improved understanding of the molecular basis for these tumors translates to the clinical realm.

Dr. Alexander L. Lazarides
Dr. Zachary D.C. Burke
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cancers is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.