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Cancers publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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The Role of Circulating Tumor Cells in Colorectal Cancer

edited by

Chiara Nicolazzo

submission deadline 31 Dec 2026 | 2 articles | Viewed by 6129 | Submission Open

Keywords: circulating tumor cells (CTC); colorectal cancer (CRC); liquid biopsy; biomarkers; tumor progression; personalized medicine; molecular profiling; metastasis; diagnostic techniques; prognostic evaluation

(This special issue belongs to the Section Cancer Biomarkers)

Molecular and Genetic Biomarkers in Oral Squamous Cell Carcinoma

edited by

Kalu U.E. Ogbureke

submission deadline 31 Dec 2026 | 3 articles | Viewed by 5845 | Submission Open

Keywords: oral cancer; oropharyngeal cancer; biomarkers; liquid biopsy; genetic determinants

(This special issue belongs to the Section Cancer Biomarkers)

Radiation Therapy in Oncology

edited by Jerzy Wydmański

submission deadline 31 Dec 2026 | 5 articles | Viewed by 5493 | Submission Open

Keywords: radiotherapy; radiation injury; systemic therapy; immunotherapy; cancer; concurrent chemoradiotherapy; stereotactic radiotherapy

(This special issue belongs to the Section Cancer Therapy)

Novel Strategies to Fight Metastatic Breast Cancer

edited by

Fernando Schmitt

and

Nuno Vale

submission deadline 31 Dec 2026 | 3 articles | Viewed by 5473 | Submission Open

Keywords: breast cancer; metastasis; targeted therapy; biomarkers; personalized medicine; prognosis

(This special issue belongs to the Section Molecular Cancer Biology)

Clinical Pathology of Lung Cancer (2nd Edition)

edited by

Letizia Gnetti

submission deadline 31 Dec 2026 | 3 articles | Viewed by 5384 | Submission Open

Keywords: lung cancer; pathology; diagnosis; treatment; targeted therapies; immunotherapy

(This special issue belongs to the Section Clinical Research in Cancer)

Cancer Cell Vulnerabilities on Pathways Regulating the Cell Cycle

edited by

Hiroaki Kiyokawa

submission deadline 31 Dec 2026 | 3 articles | Viewed by 5130 | Submission Open

Keywords: cell cycle; signaling pathway; precision medicine

(This special issue belongs to the Section Molecular Cancer Biology)

Cancer-Associated Thrombosis, Arterial and Venous Thromboembolism

edited by

Omer Iqbal

submission deadline 31 Dec 2026 | 5 articles | Viewed by 5033 | Submission Open

Keywords: cancer; deep vein thrombosis; pulmonary embolism; venous thromboembolism; anticoagulants; cardio-oncology; artificial intelligence; machine learning

(This special issue belongs to the Section Cancer Pathophysiology)

Multiple Myeloma—Biology, Diagnosis, Treatment and Prognosis (2nd Edition)

edited by

Cirino Botta

submission deadline 31 Dec 2026 | 3 articles | Viewed by 4928 | Submission Open

Keywords: multiple myeloma; bone marrow microenvironment; minimal residual disease; mass spectrometry; flow cytometry; CAR-T; bispecific agents; genomic alterations

(This special issue belongs to the Section Cancer Causes, Screening and Diagnosis)

Genetic Alterations and Features in the Development of Gastrointestinal Cancer

edited by

Alexandra Voutsina

submission deadline 31 Dec 2026 | 1 articles | Viewed by 4893 | Submission Open

Keywords: gastrointestinal cancers; genetic alteration; epigenetic regulation; the mechanism of tumorigenesis; precision treatment

(This special issue belongs to the Section Molecular Cancer Biology)

Advances in Cancer Survival Analysis

edited by

Tianhui (Thomas) Chen

, Jianguang Ji and

Jun Lyu

submission deadline 31 Dec 2026 | 3 articles | Viewed by 4785 | Submission Open

Keywords: cancer burden; cancer survival; epidemiology; survival analysis methodology; cancer screening; cancer control; cancer prognosis; cancer data mining

(This special issue belongs to the Section Cancer Survivorship and Quality of Life)

Head and Neck Cancer: MRI and PET/CT Diagnosis and Surgical Treatment

edited by

Lavinia Manuela Lenghel

submission deadline 31 Dec 2026 | 2 articles | Viewed by 4213 | Submission Open

Keywords: head and neck cancer; MRI; PET/CT; diagnostic imaging; surgical treatment; tumor staging; image-guided surgery; multidisciplinary approach; oncologic outcomes

(This special issue belongs to the Section Cancer Therapy)

Soft Tissue Sarcomas—New Diagnostic and Therapeutic Perspectives Through Clinical Genomic Profiling

edited by

Ewa Koscielniak

and

Monika Sparber-Sauer

submission deadline 31 Dec 2026 | 3 articles | Viewed by 4101 | Submission Open

Keywords: soft tissue sarcoma; molecular profiling; cancer genomics; personalized medicine

(This special issue belongs to the Section Cancer Therapy)

Molecular Advances in Lung Cancer: From Pathogenesis to Precision Therapy (2nd Edition)

edited by

Federico Pio Fabrizio

submission deadline 31 Dec 2026 | 2 articles | Viewed by 3932 | Submission Open

Keywords: lung cancer molecular biology; targeted therapy; precision medicine; biomarkers; therapeutic resistance

(This special issue belongs to the Section Molecular Cancer Biology)

Tumor Suppressor Genes and Oncogenes: Genome-Wide Insights into Cancer Biology

edited by

Meena Kanduri

submission deadline 31 Dec 2026 | 2 articles | Viewed by 3926 | Submission Open

Keywords: tumor suppressor genes; oncogenes; cancer; genome analysis; cancer mutations; DNA methylation; histone modification; cancer progression; oncogenesis

(This special issue belongs to the Section Molecular Cancer Biology)

Nanomedicine’s Role in Oncology

edited by

Efstathios Efstathopoulos

and

Ellas Spyratou

submission deadline 31 Dec 2026 | 1 articles | Viewed by 3795 | Submission Open

Keywords: nanomedicine; oncology; interventional oncology; nanotechnology development; cancer diagnosis; cancer treatment; cancer imaging

(This special issue belongs to the Section Methods and Technologies Development)

Updates on Anti-Cancer Drug Research

edited by

Ana Luísa De Sousa-Coelho

and Mónica Fernandes

submission deadline 31 Dec 2026 | 3 articles | Viewed by 3535 | Submission Open

Keywords: anti-cancer drug research; drug resistance; biomarkers; pharmacogenomics; single-cell RNA sequencing; non-coding RNAs; multi-omics data

(This special issue belongs to the Section Cancer Drug Development)

PARP Inhibitors in Cancer Therapy

edited by

Jie Jiang

and

Fu Gui

submission deadline 31 Dec 2026 | 2 articles | Viewed by 3510 | Submission Open

Keywords: PARP inhibitors; cancer therapy; DNA damage repair; drug discovery

(This special issue belongs to the Section Cancer Therapy)

Genomic and Epigenomic Aberrations in Cancer

edited by

Xiaofan Ding

submission deadline 31 Dec 2026 | 2 articles | Viewed by 3285 | Submission Open

Keywords: genomic mutation; epigenetic alteration; functional genomics

(This special issue belongs to the Section Molecular Cancer Biology)

Advanced Research in Surgical Treatment for Spinal Tumors

edited by Alessandro Gasbarrini, Stefano Bandiera and

Giuseppe Tedesco

submission deadline 31 Dec 2026 | 3 articles | Viewed by 3212 | Submission Open

Keywords: spine oncology; primary tumors; metastatic tumors; spondylectomy; en bloc resection; minimally invasive surgery; anterior reconstruction; biomaterials; radiosurgery; electrochemotherapy

(This special issue belongs to the Section Cancer Therapy)

Clinical Application of Proton Therapy and Advanced Radiotherapy in Gynecological Cancer

edited by Amy Tien Yee Chang and

Bin Yang

submission deadline 31 Dec 2026 | 4 articles | Viewed by 3175 | Submission Open

Keywords: proton therapy; cervical cancer; endometrial cancer; vaginal cancer; MR-guided radiotherapy; MR-guided brachytherapy; stereotactic body radiotherapy

(This special issue belongs to the Section Cancer Therapy)

Innovative and Personalized Approaches to Improve Patient Outcomes in Gynecological Oncology

edited by Anke Smits and James Dilley

submission deadline 31 Dec 2026 | 2 articles | Viewed by 3167 | Submission Open

Keywords: gynecological cancer; lifestyle; prehabilitation; rehabilitation; survival; quality of life

(This special issue belongs to the Section Cancer Survivorship and Quality of Life)

Advancements in Surgical and Multidisciplinary Management of Hepatopancreaticobiliary Cancers

edited by Aleksey A. Novikov

submission deadline 31 Dec 2026 | 2 articles | Viewed by 3095 | Submission Open

Keywords: fatty pancreas; pancreatic steatosis; intra-pancreatic fat deposition; pancreatic ductal adenocarcinoma; metabolic dysfunction; pancreatic imaging; oncogenesis; endoscopic ultrasound

(This special issue belongs to the Section Clinical Research in Cancer)

Unveiling the Complexity of Hepato-Biliary-Pancreatic Cancers: From Pathogenesis to Management

edited by

Stefano Cacciatore

and Luiz Zerbini

submission deadline 31 Dec 2026 | 1 articles | Viewed by 2998 | Submission Open

Keywords: hepatocellular carcinoma (HCC); cholangiocarcinoma; pancreatic ductal adenocarcinoma (PDAC); tumour microenvironment; molecular biomarkers; therapeutic resistance; cancer immunotherapy; early cancer detection; precision oncology; targeted therapy

(This special issue belongs to the Section Clinical Research in Cancer)

Advanced Research in Oncology in 2026

edited by

Dimitrios Moris

submission deadline 31 Dec 2026 | 1 articles | Viewed by 2961 | Submission Open

Keywords: cancer; tumour; oncology

Hepatocellular Carcinoma: Clinical Evidence and Emerging Therapeutic Benefits

edited by

Alessandro Loglio

submission deadline 31 Dec 2026 | 2 articles | Viewed by 2877 | Submission Open

Keywords: artificial intelligence; downstaging; immunotherapy; multidisciplinary approaches; risk factors; nutrition

(This special issue belongs to the Section Cancer Therapy)

Autophagy and Apoptosis in Cancer Progression

edited by Antonio Ieni

submission deadline 31 Dec 2026 | 1 articles | Viewed by 2841 | Submission Open

Keywords: autophagy; apoptosis; cancer progression; cell death pathways; therapeutic resistance

(This special issue belongs to the Section Molecular Cancer Biology)

Laparoscopic and Robotic Surgery for Gastrointestinal and Hepato-Pancreato-Biliary Cancers

edited by

Kosei Takagi

submission deadline 31 Dec 2026 | 2 articles | Viewed by 2728 | Submission Open

Keywords: minimally invasive surgery; laparoscopic surgery; robotic surgery; gastrointestinal cancers; hepato-pancreato-biliary cancers; neoadjuvant therapy; adjuvant therapy; outcomes

(This special issue belongs to the Section Clinical Research in Cancer)

Single-Cell Biology of Cancer

edited by

Chang Zou

submission deadline 31 Dec 2026 | 2 articles | Viewed by 2592 | Submission Open

Keywords: tumor heterogeneity; single-cell sequencing; drug resistance; tumor microenvironment; cell–cell communication; precision oncology

(This special issue belongs to the Section Molecular Cancer Biology)

Global Perspectives on the Epidemiology and Management of Early-Onset Cancers

edited by

Duke Appiah

submission deadline 31 Dec 2026 | 2 articles | Viewed by 2520 | Submission Open

Keywords: early-onset cancer; adolescent and young adult cancer (AYA); early-onset breast cancer; early-onset colorectal cancer; early-onset pancreatic cancer; early-onset thyroid cancer; early-onset melanoma; early-onset gastrointestinal cancers; early-onset hematological cancers; early-onset cancers of reproductive organs

(This special issue belongs to the Section Cancer Epidemiology and Prevention)

Overcoming the Barriers: Cellular and Molecular Pathology of Pancreatic Cancer

edited by

Jelena Grahovac

submission deadline 31 Dec 2026 | 1 articles | Viewed by 2465 | Submission Open

Keywords: pancreatic cancer; metastasis; tumor microenvironment; tumor metabolism; tumor immunity

(This special issue belongs to the Section Molecular Cancer Biology)

Advancing Therapeutic Strategies for Neuroendocrine Tumors: Towards Personalized and Multidisciplinary Care

edited by

Robert A. Ramirez

submission deadline 31 Dec 2026 | 3 articles | Viewed by 2432 | Submission Open

Keywords: neuroendocrine tumor; neuroendocrine carcinoma; multidisciplinary care; PRRT; hepatic embolization; tumor debulking; targeted therapy; lung carcinoid

(This special issue belongs to the Section Cancer Therapy)

Computational Methods for Integrative Cancer Data Analysis

edited by

Kai Li

submission deadline 31 Dec 2026 | 2 articles | Viewed by 2269 | Submission Open

Keywords: cancer bioinformatics; multi-omics integration; machine learning; translational oncology

(This special issue belongs to the Section Cancer Informatics and Big Data)

Disparities in Cancer Care: Advancing Equity Across the Cancer Continuum

edited by

Gladys Asiedu

and Ernie Kaninjing

submission deadline 31 Dec 2026 | 2 articles | Viewed by 2266 | Submission Open

(This special issue belongs to the Section Cancer Survivorship and Quality of Life)

CDK4/6 Inhibitors in Cancer: Efficacy, Resistance, and Combination Approaches

edited by

Boshi Wang

submission deadline 31 Dec 2026 | 2 articles | Viewed by 2263 | Submission Open

Keywords: CDK4/6 inhibitors; palbociclib; abemaciclib; ribociclib; cancer; senescence; combinatorial therapy; prognosis; molecular mechanisms

(This special issue belongs to the Section Cancer Therapy)

A New Road for Cancer Drug Discovery

edited by

Navnath S. Gavande

and

Yubin Ge

submission deadline 31 Dec 2026 | 3 articles | Viewed by 2261 | Submission Open

Keywords: cancer drug discovery; artificial intelligence in drug discovery and development; targeted therapy; precision oncology; targeted protein degrades; small-molecule therapeutics; immuno-oncology; undruggable targets; drug resistance mechanisms; combination therapy

(This special issue belongs to the Section Cancer Drug Development)

The Impact of Minimally Invasive Surgery on Gynecologic Cancers

edited by

Gabriel Levin

submission deadline 31 Dec 2026 | 1 articles | Viewed by 2170 | Submission Open

Keywords: minimally invasive surgery; robotic-assisted surgery; gynecologic malignancy; laparoscopy

(This special issue belongs to the Section Cancer Therapy)

Pathogenesis and Treatment Strategies in Multiple Myeloma: From Basic Research to Real Life: 2nd Edition

edited by Shingen Nakamura

submission deadline 31 Dec 2026 | 1 articles | Viewed by 2128 | Submission Open

Keywords: myeloma bone disease; denosumab; bisphosphonate; infectious complication; proteasome inhibitor; IMiDs; anti-CD38 antibody; venetoclax; immunotherapy

(This special issue belongs to the Section Cancer Therapy)

Next-Generation Boron Neutron Capture Therapy (BNCT) for Cancer Treatment

edited by Dayron Ramos López, Gabriella Pugliese and Raffaella Radogna

submission deadline 31 Dec 2026 | 1 articles | Viewed by 1961 | Submission Open

Keywords: BNCT; boron agents; dosimetry; neutron detectors; cancer therapy; imaging; simulation; neutron sources; treatment planning; medical physics

(This special issue belongs to the Section Methods and Technologies Development)

Molecular Mechanisms of Cancer Progression and Metastasis

edited by

Babak Behnam

submission deadline 31 Dec 2026 | 1 articles | Viewed by 1935 | Submission Open

Keywords: metastasis; molecular mechanisms; tumor microenvironment (TME); epithelial-to-mesenchymal transition (EMT); cancer stem cell; therapeutic strategies; immune evasion

(This special issue belongs to the Section Cancer Metastasis)

Emerging Therapies for Germ Cell Tumors

edited by

Ratnakar Singh

and Krinio Giannikou

submission deadline 31 Dec 2026 | 1 articles | Viewed by 1874 | Submission Open

Keywords: testicular cancer; embryonal carcinoma; germ cell tumors; cisplatin; immunotherapy; epigenetics; microRNA; chemoresistance; animal models; targeted therapy

(This special issue belongs to the Section Cancer Therapy)

Advancements in Head and Neck Cancer Surgery (2nd Edition)

edited by

Carlos M. Chiesa-Estomba

submission deadline 31 Dec 2026 | 2 articles | Viewed by 1864 | Submission Open

Keywords: minimal invasive; transoral; robotic; reconstructive; 3D printing; targeting therapies; imaging

Evolving Management of Gastroesophageal Cancers: From Local Therapies to Precision Oncology

edited by Matthew Strickland

submission deadline 31 Dec 2026 | 1 articles | Viewed by 1834 | Submission Open

Keywords: gastric cancer; esophageal cancer; immunotherapy targeted therapy; radiation therapy; surgical oncology; precision oncology; molecular biomarkers; multimodal treatment

(This special issue belongs to the Section Cancer Therapy)

Exploring the Processes of Biochemical, Cellular and Molecular Drivers of Cancer Cell and Emerging Therapies

edited by

Amit Kunwar

submission deadline 31 Dec 2026 | 1 articles | Viewed by 1710 | Submission Open

Keywords: redox biology; metabolism; signal transduction; genetics; drug discovery; drug delivery; drug resistance; nanotherapeutics; diagnostic sensors; clinical trial

The Evolving Role of CDK4/6 Inhibitors in Early and Recurrent Breast Cancer: Clinical and Translational Findings and Work in Progress

edited by Hans-Christian Kolberg

submission deadline 31 Dec 2026 | 1 articles | Viewed by 1532 | Submission Open

Keywords: CDK4/6 inhibitors; breast cancer; treatment resistance; combination therapy; biomarkers

Artificial Intelligence and Machine Learning in Cancer Diagnosis, Treatment, and Prognosis

edited by Iakovos Amygdalos

submission deadline 31 Dec 2026 | 1 articles | Viewed by 1508 | Submission Open

Keywords: artificial intelligence in oncology and oncological surgery; machine learning for cancer diagnosis; multimodal data integration; precision oncology and prognostic modeling; federated and explainable AI

(This special issue belongs to the Section Methods and Technologies Development)

Innovations in Cutaneous Oncology and Dermatologic Surgery: Translating Mechanisms into Practice

edited by Paulo Filipe and Maria Catorze

submission deadline 31 Dec 2026 | 1 articles | Viewed by 1434 | Submission Open

Keywords: cutaneous oncology; dermatologic surgery; mohs micrographic surgery; immunotherapy; hedgehog pathway; translational research; skin cancer; digital innovation

(This special issue belongs to the Section Cancer Therapy)

Molecular Mechanisms of Breast Cancer Treatment-Related Side Effects and Precision Interventions

edited by

Jennifer Hu

submission deadline 31 Dec 2026 | 1 articles | Viewed by 1386 | Submission Open

Keywords: breast cancer; treatment-related side effects; biomarker; precision interventions

(This special issue belongs to the Section Cancer Therapy)

Advances in Dermoscopy for Melanoma and Non-Melanoma Skin Cancer

edited by

Clay J. Cockerell

, Warren Chan, Jade Conway and

Iman Ali

submission deadline 31 Dec 2026 | 2 articles | Viewed by 1319 | Submission Open

Keywords: dermoscopy; skin cancer; diagnosis; artificial intelligence; multimodal imaging; teledermoscopy

(This special issue belongs to the Section Cancer Causes, Screening and Diagnosis)

The Role of Minimally Invasive and Minimally Radical Surgery in Cervical and Endometrial Cancer

edited by

Raj Naik

Marie Plante

, Christophe Pomel,

Roberto Tozzi

and Gwénaël Ferron

submission deadline 31 Dec 2026 | 1 articles | Viewed by 1272 | Submission Open

Keywords: cervical cancer; endometrial cancer; laparoscopic surgery; minimally invasive surgery; surgical oncology; fertility-sparing surgery; non-radical surgery; conservative surgery

(This special issue belongs to the Section Cancer Therapy)

Lung Cancer Risk, Disparities, and Outcomes: From Epidemiology to Multimodality Care

edited by Jeffrey B. Velotta

submission deadline 31 Dec 2026 | 1 articles | Viewed by 1260 | Submission Open

Keywords: lung cancer epidemiology; non-smoking risk factors; health disparities; gender differences; biomarkers; AI risk models; multimodality care; family history; real-world outcomes

Displaying special issue 451-500 on page 10 of 21.

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