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Cancers publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Novel Strategies in the Prevention/Treatment of Colorectal Cancer: 2nd Edition
edited by
submission deadline 20 Jun 2026 | Viewed by 10 | Submission Open
Keywords: colorectal cancer; chemotherapy; chemoprevention; targeted therapy; kinase inhibitor; immunotherapy
Angiogenesis and Anti-Angiogenic Therapies in Cancer
edited by and Giovanni Mastrandrea
submission deadline 24 Jun 2026 | Viewed by 116 | Submission Open
Keywords: angiogenesis; anti-angiogenic therapies; cancer; tumor vasculature; therapeutic strategies
(This special issue belongs to the Section Tumor Microenvironment)
Advances in Soft Tissue and Bone Sarcoma (2nd Edition) submission deadline 25 Jun 2026 | 3 articles | Viewed by 2847 | Submission Open
Keywords: bone sarcoma; soft tissue sarcoma; prognosis; diagnosis; detection; molecular biomarkers; histopathology; treatment
(This special issue belongs to the Section Cancer Therapy)
Digital Pathology in Precision Oncology: Emerging Tools for Diagnosis and Treatment Guidance
edited by Daniela Hartmann and
submission deadline 25 Jun 2026 | Viewed by 176 | Submission Open
Keywords: dermatology  ; digital pathology  ; ex vivo confocal microscopy  ; artificial intelligence  ; machine learning  ; virtual biopsy  ; teledermatology  ; histopathological images; image analysis algorithms
(This special issue belongs to the Section Cancer Causes, Screening and Diagnosis)
Clinical and Translational Research in Head and Neck Cancer—2nd Edition
edited by Young J. Kim
submission deadline 25 Jun 2026 | Viewed by 84 | Submission Open
Keywords: head and neck cancer; immunotherapy; translation; combinatorial clinical trials; oncologic therapeutics
(This special issue belongs to the Section Clinical Research of Cancer)
Surgery for Thoracic Cancer
edited by Andrea Billé and Louisa Patel
submission deadline 25 Jun 2026 | Viewed by 72 | Submission Open
Keywords: thoracic surgery; lung cancer; mesothelioma; thymic malignancies; minimally invasive surgery; robotic-assisted thoracic surgery; multimodal therapy; immunotherapy; perioperative management; surgical outcomes
(This special issue belongs to the Section Cancer Therapy)
Immune Deficiency-Associated Lymphoma submission deadline 25 Jun 2026 | Viewed by 29 | Submission Open
Keywords: lymphoma; immune; HIV infection
(This special issue belongs to the Section Cancer Immunology and Immunotherapy)
Advances in the Diagnosis, Stratification, and Targeted Treatment of Myeloproliferative Neoplasms submission deadline 25 Jun 2026 | Viewed by 18 | Submission Open
Keywords: myeloproliferative neoplasms; molecular diagnostics; targeted therapy; mutational profiling; biomarkers; disease progression; therapy resistance; translational research; personalized medicine
Epigenetic and Metabolic Alterations in the Tumor Microenvironment: 2nd Edition submission deadline 26 Jun 2026 | 1 articles | Viewed by 2478 | Submission Open
Keywords: tumor microenvironment; hypoxia; inflammation; cytokines; epigenetics; metabolic cross-talk; cancer stroma cells; epigenetic alterations; cancer cell dormancy; cancer cell proliferation; cancer cell migration; cancer cell stemness
(This special issue belongs to the Section Tumor Microenvironment)
New Strategies for Molecular Targeted Therapy in Multiple Myeloma
edited by Daniele Caracciolo
submission deadline 26 Jun 2026 | 1 articles | Viewed by 949 | Submission Open
Keywords: multiple myeloma; molecular target; drug target; signaling pathway; immunotherapeutic strategy; drug resistance
(This special issue belongs to the Section Cancer Therapy)
Clinical Epidemiology and Risk Prediction for Gastrointestinal Cancers submission deadline 30 Jun 2026 | 11 articles | Viewed by 36212 | Submission Open
Keywords: gastrointestinal cancers; genetic risk; polygenic risk scores; exposome; lifestyle risk factors; biomarkers; chemoprevention
(This special issue belongs to the Section Cancer Epidemiology and Prevention)
Hematologic Malignancies and Related Disorders: Challenges from Diagnosis to Treatment submission deadline 30 Jun 2026 | 9 articles | Viewed by 24301 | Submission Open
Keywords: hematopoietic cell transplantation; cell therapy; acute myeloid leukemia; graft-versus-host disease; hematologic malignancies; thrombosis; complement; lymphoma; myeloma; COVID-19
(This special issue belongs to the Section Cancer Therapy)
New Challenges for Gastric Cancer—Gut Microbiota, Post-eradication and Chemotherapy
edited by Kazunari Murakami and
submission deadline 30 Jun 2026 | 7 articles | Viewed by 23919 | Submission Open
Keywords: gastric cancer; microbiota; Helicobacter pylori; after Helicobacter pylori eradication therapy; chemotherapy; immune checkpoint inhibitor
(This special issue belongs to the Section Cancer Therapy)
Advances in the Prevention and Treatment of Liver Cancer
edited by Ewa Janczewska
submission deadline 30 Jun 2026 | 8 articles | Viewed by 22917 | Submission Open
Keywords: new screening techniques; enhanced imaging; biomarker tests; radiofrequency ablation; transarterial chemoembolization
(This special issue belongs to the Section Cancer Therapy)
Advances in Bacteria and Cancer
edited by
submission deadline 30 Jun 2026 | 5 articles | Viewed by 18267 | Submission Open
Keywords: pathogenic bacteria; microbiota; tumor-associated bacteria; probiotics; oncogenesis; metastasis; chemotherapy; cancerous cells; tumor microenvironment; cell signaling
(This special issue belongs to the Section Tumor Microenvironment)
Advances in Epidermal Growth Factor Receptor-Driven Non-Small-Cell Lung Cancer: Diagnostic Technologies and Therapeutic Strategies
edited by
submission deadline 30 Jun 2026 | 4 articles | Viewed by 15800 | Submission Open
Keywords: EGFR-targeted therapy; non-small-cell lung cancer diagnosis; diagnostic technologies and devices; biological discoveries in NSCLC; AI-assisted diagnosis in oncology; clinical practice in NSCLC detection; therapeutic– diagnostic integration; early-stage lung cancer monitoring; advanced NSCLC diagnostic approaches; precision medicine in lung cancer
(This special issue belongs to the Section Cancer Causes, Screening and Diagnosis)
Gynecologic Oncology: Clinical and Translational Research
edited by , Pasquale Lombardi and Gaia Giannone
submission deadline 30 Jun 2026 | 7 articles | Viewed by 14286 | Submission Open
Keywords: gynecological cancer; ovarian cancer; translational research; effectiveness; toxicity; immunotherapy; PARP inhibitors
(This special issue belongs to the Section Cancer Therapy)
New Insights into Thyroid Cancer Surgery
edited by and Francesca Torresan
submission deadline 30 Jun 2026 | 6 articles | Viewed by 14104 | Submission Open
Keywords: total thyroidectomy; differentiated thyroid cancer; lymph node dissection; parathyroid autofluorescence; medullary thyroid carcinoma; recurrent laryngeal nerve neuromonitoring
(This special issue belongs to the Section Cancer Therapy)
Role of Cancer Biomarkers for Diagnosis, Prognosis and Targeted Therapy in Gastrointestinal Cancers
edited by
submission deadline 30 Jun 2026 | 8 articles | Viewed by 11766 | Submission Open
Keywords: liquid biopsy; esophageal cancer; gastric cancer; colorectal cancer; pancreatic cancer; hepatocellular cancer; appendiceal cancer; cancer biomarker; DNA sequencing; transcriptomics; proteomics; immunohistochemistry
(This special issue belongs to the Section Cancer Biomarkers)
Updates on Urologic Oncology: From Diagnosis to Localized and Systemic Therapy Options (2nd Edition)
edited by
submission deadline 30 Jun 2026 | 4 articles | Viewed by 10613 | Submission Open
Keywords: bladder cancer; prostate cancer; renal cancer; urologic cancer treatment; urologic cancer diagnosis; urologic cancer innovation; urologic neoplasm therapy; immunotherapy
(This special issue belongs to the Section Cancer Therapy)
Clinical Diagnosis, Treatment, and Prognosis of Uveal Melanoma
edited by Josep Maria Caminal Mitjana
submission deadline 30 Jun 2026 | 5 articles | Viewed by 10255 | Submission Open
Keywords: uveal melanoma; choroidal melanoma; gene expression profiling; immunotherapy; metastasis; radiotherapy; liquid biopsy; circulating tumor cells; brachytherapy; next-generation sequencing; proton therapy
(This special issue belongs to the Section Cancer Causes, Screening and Diagnosis)
Gastrointestinal Cancer Surgery
edited by Florian Primavesi and
submission deadline 30 Jun 2026 | 6 articles | Viewed by 9967 | Submission Open
Keywords: gastrointestinal cancer surgery; precision surgery; personalized medicine; robotics; pathology; colorectal cancer; stomach cancer; pancreatic cancer; hepatocellular cancer; biliary tract cancer
(This special issue belongs to the Section Cancer Therapy)
News and How Much to Improve in Management of Soft Tissue Sarcomas
edited by Vicente Artigas-Raventós and
submission deadline 30 Jun 2026 | 5 articles | Viewed by 9359 | Submission Open
Keywords: soft tissue sarcomas; prevalent types; multidisciplinary board; reference centers; news diagnosis methods and treatments; implication of IA and 3D in sarcomas; implication of minimally aggressive surgical techniques
(This special issue belongs to the Section Cancer Therapy)
Application of Artificial Intelligence-Based Approaches in Cancer Diagnosis, Treatment and Prognosis
edited by
submission deadline 30 Jun 2026 | 6 articles | Viewed by 9151 | Submission Open
Keywords: cancer genomics; artificial intelligence; machine learning; deep learning; tumor microenvironment; graph-based convolutional neural network; computational cancer biology
(This special issue belongs to the Section Methods and Technologies Development)
The Progress of Pancreatectomy for Pancreatic Cancer Treatment submission deadline 30 Jun 2026 | 5 articles | Viewed by 9096 | Submission Open
Keywords: pancreatic ductal adenocarcinoma (PDAC); pancreatectomy timing in multimodal regimen; minimally invasive pancreatectomy for PDAC; pancreatectomy and resectability; extended pancreatectomy; vascular resection and reconstruction; outcome research— pancreatectomy for cancer in unselected patient cohorts; interaction of postoperative complications and preoperative or adjuvant therapy; postoperative pancreatic fistula
(This special issue belongs to the Section Clinical Research of Cancer)
Human Papillomavirus (HPV) and Related Cancer
edited by
submission deadline 30 Jun 2026 | 4 articles | Viewed by 8919 | Submission Open
Keywords: HPV; carcinogenesis; methods of virus identification diagnostics; prognostification
(This special issue belongs to the Section Infectious Agents and Cancer)
The Role of Neutrophils in Tumor Progression and Metastasis
edited by and Leah M. Cook
submission deadline 30 Jun 2026 | 5 articles | Viewed by 8187 | Submission Open
Keywords: neutrophils; innate immunity; tumor; microenvironment; metastasis; targeted therapeutics
(This special issue belongs to the Section Cancer Metastasis)
Epigenetic Regulation in Hematologic Malignancies
edited by Travis S. Johnson
submission deadline 30 Jun 2026 | 3 articles | Viewed by 7529 | Submission Open
Keywords: epigenetic regulation; hematologic malignancies; DNA methylation; non-coding RNA; therapeutic targeting
(This special issue belongs to the Section Tumor Microenvironment)
Advances in Abdominal Surgical Oncology and Intraperitoneal Therapies submission deadline 30 Jun 2026 | 5 articles | Viewed by 7457 | Submission Open
Keywords: abdominal oncologic surgery; minimally invasive techniques; laparoscopy; robotics; fluorescence; artificial intelligence; augmented vision; peritoneal carcinomatosis; intraperitoneal chemotherapy; liquid biopsy
(This special issue belongs to the Section Cancer Therapy)
Perspectives on the Efficacy and Biomarkers of Immunotherapy and Targeted Therapy for Patients with Colorectal Cancer submission deadline 30 Jun 2026 | 2 articles | Viewed by 7300 | Submission Open
Keywords: colorectal cancer; precision medicine; targeted therapeutics; immunotherapy; KRAS; BRAF; HER2; biomarkers
(This special issue belongs to the Section Cancer Therapy)
Recent Advances in Hematological Malignancies in Children submission deadline 30 Jun 2026 | 3 articles | Viewed by 6563 | Submission Open
Keywords: acute lymphoblastic leukemia; acute myeloid leukemia; hematological malignancies in children; diagnostic and therapeutic methods; supportive care strategies
(This special issue belongs to the Section Pediatric Oncology)
Novel Diagnosis and Treatment Approaches in Pancreatic Cancer
edited by
submission deadline 30 Jun 2026 | 3 articles | Viewed by 5812 | Submission Open
Keywords: pancreatic cancer; pancreatic fibrosis; biomarker; risk factor; genetic testing; artificial intelligence; endoscopic ultrasound; stroma; cancer-associated fibroblasts; familial pancreatic cancer
(This special issue belongs to the Section Cancer Therapy)
Advancements in the Diagnosis and Surgical Treatment of Prostate Cancer
edited by and Christian Thomas
submission deadline 30 Jun 2026 | 3 articles | Viewed by 5772 | Submission Open
Keywords: robotic-assisted radical prostatectomy; significance of pelvic lymph node dissection in the context of radical prostatectomy; complications of surgical therapy for prostate cancer; magnetic resonance imaging/ultrasound-guided target biopsy of the prostate; comparison of various robotic systems for radical prostatectomy; learning curves; hospital volume; prostate cancer centers
(This special issue belongs to the Section Clinical Research of Cancer)
Exploring Immunotherapy in Colorectal Cancer submission deadline 30 Jun 2026 | 1 articles | Viewed by 5451 | Submission Open
Keywords: colorectal cancer; immunotherapy; immune checkpoint inhibitors; mismatch repair; microsatellite instability; biomarkers
(This special issue belongs to the Section Cancer Immunology and Immunotherapy)
Applications of Ex Vivo Microscopy in Cancer Detection and Diagnosis
edited by J. Quincy Brown
submission deadline 30 Jun 2026 | 4 articles | Viewed by 4728 | Submission Open
Keywords: microscopy; cancer; optical sectioning; diagnosis; detection
(This special issue belongs to the Section Cancer Causes, Screening and Diagnosis)
Advances in Cancer Data and Statistics: 2nd Edition
edited by
submission deadline 30 Jun 2026 | 3 articles | Viewed by 4392 | Submission Open
Keywords: cancer registries; cancer incidence; cancer survival; population-based studies; cancer risk factors
(This special issue belongs to the Section Cancer Informatics and Big Data)
Cancer Mechanosensing
edited by Meenal Datta and Xin Tang
submission deadline 30 Jun 2026 | 1 articles | Viewed by 4038 | Submission Open
Keywords: cancer mechanosensing; mechanotransduction; mechanical cues; mechanosensitive ion channels; focal adhesions; cytoskeletal elements; tumor microenvironments; fluid shear stress; stiffness; cell compression; tumor progression; metastasis; drug resistance; immune response; biophysical tools
(This special issue belongs to the Section Cancer Pathophysiology)
Integrating Precision Medicine with Nanotechnology to Overcome Drug Resistance in Cancer
edited by Yan Li
submission deadline 30 Jun 2026 | 1 articles | Viewed by 3776 | Submission Open
Keywords: precision medicine; nanotechnology; drug resistance
(This special issue belongs to the Section Methods and Technologies Development)
Advances in PET/CT for Predicting Cancer Outcomes
edited by Ahmad Shariftabrizi
submission deadline 30 Jun 2026 | 1 articles | Viewed by 3490 | Submission Open
Keywords: FDG PET/CT; PSMA PET/CT; dotatate PET/CT; tumor heterogeneity; radiomics; CAR T-cell therapy; rare tumors; radiogenomics; immunotherapy; targeted therapy; PET physics; radiotracer metabolism
(This special issue belongs to the Section Methods and Technologies Development)
Neurosurgical Advances in Brain Tumor Surgery
edited by Camilla Bonaudo, Alessandro Della Puppa and
submission deadline 30 Jun 2026 | 2 articles | Viewed by 3396 | Submission Open
Keywords: brain lesions/tumors; preoperative mapping; neuro-oncology; navigated TMS (n TMS); brain stimulation; optical imaging; cognitive mapping; awake surgery; functional mapping; functional preservation; intraoperative monitoring; neurophysiological monitoring
(This special issue belongs to the Section Clinical Research of Cancer)
Neuroscience of Brain Tumors
edited by Zefferino Rossini, and Maria Pia Tropeano
submission deadline 30 Jun 2026 | 2 articles | Viewed by 3252 | Submission Open
Keywords: neurosurgery; neuroscience; brain tumors (gliomas; meningiomas; and pituitary tumors); neural pathway; neuroimaging; neurogenetics
(This special issue belongs to the Section Molecular Cancer Biology)
Clinical Applications of Precision Diagnosis for Thyroid Cancers and Its Clinical Use for Treatments Choice
edited by , Silvia Martina Ferrari and
submission deadline 30 Jun 2026 | 2 articles | Viewed by 2995 | Submission Open
Keywords: thyroid cancer; precision diagnosis; clinical management; molecular tests; molecular therapeutic targets; thyroid cancer epidemiology; artificial intelligence; health inequalities
(This special issue belongs to the Section Clinical Research of Cancer)
Classification, Risk Assessment and Clinical Management of Malignant Thyroid Nodules: 2nd Edition
edited by Claudio Spinelli and Marco Ghionzoli
submission deadline 30 Jun 2026 | 3 articles | Viewed by 2933 | Submission Open
Keywords: thyroid nodule; thyroid cancer; guidelines; surgery
(This special issue belongs to the Section Clinical Research of Cancer)
Chemoprevention Advances in Cancer (2nd Edition)
edited by
submission deadline 30 Jun 2026 | 2 articles | Viewed by 2863 | Submission Open
Keywords: cancer prevention; chemoprevention; nutrition and cancer; bio-active food components; natural products; non-toxic anticancer agents; precision nutrition in cancer; tumor metabolomics; gut microbiome in cancer
(This special issue belongs to the Section Cancer Epidemiology and Prevention)
New Strategies for the Treatment of Melanoma and Non-Melanoma Skin Cancer submission deadline 30 Jun 2026 | 2 articles | Viewed by 2800 | Submission Open
Keywords: melanoma; non-melanoma skin cancer; immunotherapy; anti-PD-1 antibody; BRAF/MEK inhibitors; racial differences; prognosis
(This special issue belongs to the Section Cancer Therapy)
Feature Review Papers on Cancer Epidemiology, Disparities, and Prevention
edited by Adam Barsouk
submission deadline 30 Jun 2026 | 1 articles | Viewed by 2423 | Submission Open
Keywords: epidemiology; disparities; oncology; cancer; prevention
(This special issue belongs to the Section Cancer Epidemiology and Prevention)
Advances in Neurofibromatosis
edited by Yunjia Chen and Yulong Fu
submission deadline 30 Jun 2026 | 2 articles | Viewed by 2250 | Submission Open
Keywords: neurofibromatosis; schwannomatosis; NF1; NF2; SMARCB1; LZTR1
(This special issue belongs to the Section Molecular Cancer Biology)
Clinical Pathology of Lung Cancer (2nd Edition)
edited by
submission deadline 30 Jun 2026 | 2 articles | Viewed by 2114 | Submission Open
Keywords: lung cancer; pathology; diagnosis; treatment; targeted therapies; immunotherapy
(This special issue belongs to the Section Clinical Research of Cancer)
Molecular Pathology and Human Cancers
edited by Stefano Marletta, Alessandro Russo and Giuliana Pavone
submission deadline 30 Jun 2026 | 2 articles | Viewed by 2111 | Submission Open
Keywords: molecular pathology; cancer pathogenesis; targeted therapy; personalized medicine; cancer signaling
(This special issue belongs to the Section Cancer Pathophysiology)
Challenges and New Developments in the Diagnosis and Treatment of Sarcoma
edited by
submission deadline 30 Jun 2026 | 1 articles | Viewed by 1924 | Submission Open
Keywords: bone and soft tissue sarcoma; prognostic and predictive biomarker; transcriptomic/genomic profiling; immunotherapy; targeted treatment
(This special issue belongs to the Section Cancer Therapy)
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