New Strategies for Molecular Targeted Therapy in Multiple Myeloma
A special issue of Cancers (ISSN 2072-6694). This special issue belongs to the section "Cancer Therapy".
Deadline for manuscript submissions: 26 June 2026 | Viewed by 9
Special Issue Editor
Interests: multiple myeloma; genomic instability; DNA damage response; DNA repair inhibitors
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Multiple myeloma (MM) remains an incurable hematological malignancy despite significant advancements in treatment. The last two decades have witnessed a revolution in MM therapy, driven by the introduction of novel agents such as proteasome inhibitors, immunomodulatory drugs, and monoclonal antibodies. However, the development of drug resistance and disease relapse continues to pose substantial challenges, highlighting the urgent need for more effective and precisely targeted therapeutic approaches.
This Special Issue, "New Strategies for Molecular Targeted Therapy in Multiple Myeloma", will gather cutting-edge research exploring innovative molecular targets and therapeutic strategies to overcome current limitations and improve patient outcomes. We invite submissions that delve into the identification and validation of novel molecular targets, the development of new small molecules and biologics, and advanced cellular therapies designed to precisely disrupt key oncogenic pathways in MM.
Topics of interest include, but are not limited to, the following:
- Novel drug targets and signaling pathways in multiple myeloma;
- Preclinical and translational studies of new molecularly targeted agents;
- Innovative immunotherapeutic strategies, including CAR T-cells, bispecific antibodies, and vaccine approaches;
- Approaches to overcoming drug resistance in MM;
- Combination therapies leveraging molecularly targeted agents;
- Biomarkers for patient selection and response prediction;
- Genetic and epigenetic vulnerabilities in myeloma cells.
We welcome original research articles, reviews, and short communications that contribute to our understanding of MM biology and pave the way for next-generation targeted therapies. Join us in advancing the fight against multiple myeloma by submitting your latest findings to this pivotal Special Issue.
Dr. Daniele Caracciolo
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cancers is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- multiple myeloma
- molecular target
- drug target
- signaling pathway
- immunotherapeutic strategy
- drug resistance
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