Role of Cancer Biomarkers for Diagnosis, Prognosis and Targeted Therapy in Gastrointestinal Cancers
A special issue of Cancers (ISSN 2072-6694). This special issue belongs to the section "Cancer Biomarkers".
Deadline for manuscript submissions: 13 June 2025 | Viewed by 1503
Special Issue Editor
Interests: esophageal cancer; development therapeutics; precision medicine; lung cancer; surveillance; early detection; disease monitoring; treatment response and immunotherapy
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
In recent years, cancer biomarkers have played a critical role in promoting personalized medicine and improving outcomes for patients with cancer by addressing critical unmet needs in their clinical management paradigms. In this context, biomarker-based cancer diagnosis is budding as one of the most promising ways for early detection, recurrence detection, disease progression monitoring, and effective cancer therapy. Gastrointestinal cancers account for 26% of the global cancer incidence burden and 35% of all cancer-related deaths. According to the World Health Organization, in 2018, there were an estimated 4.8 million new cases of cancer and 3.4 million related deaths worldwide. Therefore, the urgent development of novel and accurate biomarkers is necessary for enhancing screening and early detection, to better predict prognosis and identify novel therapeutic targets.
This Special Issue focuses on the need to find more meaningful gastrointestinal cancer biomarkers and druggable targets based on originality, importance, and timeliness. We welcome original research, reviews and clinical trials related but not limited to the following aspects:
- Development of novel screening and early detection biomarkers—SCED and MCED approaches;
- Identification and validation of clinically significant novel biomarkers to predict therapy response and prognosis of gastrointestinal cancer;
- Data analysis and validation identifying the novel features of gastrointestinal cancer to better guide future treatment;
- Underlying mechanisms of recurrence or metastasis of gastrointestinal cancer;
- Identification of therapeutic targets in gastrointestinal cancers.
We look forward to hearing from you.
Dr. Ali Zaidi
Guest Editor
Manuscript Submission Information
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Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cancers is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- liquid biopsy
- esophageal cancer
- gastric cancer
- colorectal cancer
- pancreatic cancer
- hepatocellular cancer
- appendiceal cancer
- cancer biomarker
- DNA sequencing
- transcriptomics
- proteomics
- immunohistochemistry
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