Harnessing Protein Design and Engineering for Therapeutic Applications
A special issue of Biomolecules (ISSN 2218-273X). This special issue belongs to the section "Molecular Structure and Dynamics".
Deadline for manuscript submissions: 31 August 2024 | Viewed by 134
Special Issue Editors
Interests: protein design and evolution; protein-protein interactions
Interests: chemical protein synthesis; peptide chemistry; selenoproteins; posttranslational protein modification
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Protein engineering, a cornerstone of molecular biology and biotechnology, plays a crucial role in tailoring proteins for diverse applications, particularly in therapeutics. This Special Issue explores the latest advancements in protein engineering methodologies aimed at optimizing protein properties for therapeutic interventions. This Special Issue presents studies that engineer therapeutic proteins and improve therapeutic protein stability, affinity, specificity, and pharmacokinetics. The contributions of this Special Issue highlight the multifaceted approaches employed, including rational design and directed evolution methods, augmented by computational techniques such as artificial intelligence. In addition, the field of chemical protein synthesis has reached a level in which large proteins, with different posttranslational modifications are now accessible, opening new horizons in chemical biology and medicinal chemistry. We welcome original manuscripts and reviews that shed light on protein engineering, protein synthesis, and design and its implications for therapeutic innovation.
Dr. Julia Shifman
Dr. Norman Metanis
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biomolecules is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- therapeutic peptides and proteins
- protein design and engineering
- chemical protein synthesis
- chemoselective protein modification
- posttranslational protein modification
Planned Papers
The below list represents only planned manuscripts. Some of these manuscripts have not been received by the Editorial Office yet. Papers submitted to MDPI journals are subject to peer-review.
Title: A review on the topic of Protein Design for Therapeutic Applications
Authors: Hyunsoo Kim
Affiliation: Chungnam National University
Title: enzyme engineering for therapeutic applications
Authors: Sagar Khare
Affiliation: Rutgers university
