Special Issues

Biomolecules publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

Section
Search by Title/Keyword
 
Order results
Display
Results per page
Molecular Mechanisms and Novel Treatments of Atherosclerosis
edited by
submission deadline 10 Feb 2027 | 2 articles | Viewed by 1044 | Submission Open
Keywords: atherosclerosis; plaque; plaque vulnerability; inflammation; immunomodulation; immune cells; multi-omics; imaging; management and therapeutics; targeted therapies
(This special issue belongs to the Section Lipids)
Purinergic Signalling in Disease and Inflammation
edited by Andréia Machado Cardoso
submission deadline 10 Feb 2027 | Viewed by 216 | Submission Open
Keywords: purinergic signalling; inflammation; ATP and adenosine; P1 receptors; P2 receptors; ectonucleotidases; chronic diseases; neurodegeneration; exercise physiology; translational research
(This special issue belongs to the Section Molecular Biology)
Novel Signaling Pathways in Cardiometabolic Diseases
edited by
submission deadline 14 Feb 2027 | Viewed by 284 | Submission Open
Keywords: metabolic disorder; hypertension; stroke; cardiovascular disease; molecular mechanisms; hypertrophy; fibrosis; lipotoxiocity; mitochondrial function; inflammation
(This special issue belongs to the Section Biological Factors)
Perspectives on Cancer Drug Resistance
edited by Vinagolu K. Rajasekhar and
submission deadline 15 Feb 2027 | Viewed by 40 | Submission Open
Keywords: cancer drug resistance; targeted therapy resistance; immunotherapy resistance; EGFR-TKI resistance; tumor microenvironment; epigenetic regulation; ion channels in cancer; metabolic reprogramming; combination therapy
(This special issue belongs to the Section Molecular Medicine)
Exploring the Pathophysiology of Epilepsy: Metabolic Mechanisms and Therapeutic Potential
edited by and Christoph Baumgartner
submission deadline 28 Feb 2027 | 5 articles | Viewed by 5935 | Submission Open
Keywords: epilepsy; metabolic regulation; signaling pathways; kynurenic acid; seizure detection; antiseizure drugs; innovative therapies
(This special issue belongs to the Section Molecular Medicine)
Wound Repair and Regeneration: From Molecular and Cellular Mechanisms to New Approaches
edited by Elia Ranzato
submission deadline 28 Feb 2027 | 4 articles | Viewed by 4513 | Submission Open
Keywords: wound repair; tissue regeneration; molecular mechanisms; cellular mechanisms; chronic wounds; fibrosis/scarring; biomaterials; stem cells; translational therapies
(This special issue belongs to the Section Molecular Medicine)
Biomarkers and Therapeutic Approaches in Melanoma: New Omics-Strategies submission deadline 28 Feb 2027 | 2 articles | Viewed by 3816 | Submission Open
Keywords: melanoma; biomarkers; omics; precision oncology; drug resistance
(This special issue belongs to the Section Molecular Biomarkers)
Exercise Immunology: Molecular Mechanisms and Health Applications
edited by , , Michał Sławiński and
submission deadline 28 Feb 2027 | 3 articles | Viewed by 3587 | Submission Open
Keywords: post-effort immune response; lifestyle-associated molecular patterns; damage-associated molecular patterns; immune cell; cell signaling; cell death; growth factor; chemokines; cytokines; transcription factors
(This special issue belongs to the Section Molecular Biology)
Exploration of Drug Targets for Liver Fibrosis Based on Hepatic Stellate Cells and Extracellular Matrix Remodeling
edited by
submission deadline 28 Feb 2027 | 2 articles | Viewed by 1802 | Submission Open
Keywords: liver fibrosis; collagen; hepatic stellate cells; senescence; animal models; extracellular matrix; hepatitis; cytokines; biomarkers; MASH; MASLD; cirrhosis; hepatocellular carcinoma
(This special issue belongs to the Section Molecular Medicine)
Membrane Clusters in Health and Neurodegenerative Disease
edited by Tayuan Chang and Catherine C. Y. Chang
submission deadline 28 Feb 2027 | 1 articles | Viewed by 1519 | Submission Open
Keywords: membrane cluster; membrane lipids; membrane proteins; caveolin; lipid rafts; phospholipid; cholesterol; sphingolipids; cholesteryl esters
Emerging Roles of Non-Coding RNAs in Gene Regulation and Disease submission deadline 28 Feb 2027 | 3 articles | Viewed by 1465 | Submission Open
Keywords: non-coding RNAs; gene expression regulation; miRNA-based therapeutics; translational RNA research
(This special issue belongs to the Section Molecular Biology)
New Discoveries in the Field of Neuropharmacology: 2nd Edition
edited by and Bogdan Amuzescu
submission deadline 28 Feb 2027 | 3 articles | Viewed by 1324 | Submission Open
Keywords: neurologic and psychiatric diseases pharmacology; in silico drug screening; in vitro pharmacology assays; animal models; neuropharmacogenomics; drug safety; blood brain barrier; electrophysiology; patch-clamp
(This special issue belongs to the Section Molecular Medicine)
Advancing Innovations in Biomedical Research for Translational Applications: 2nd Edition
edited by Jianjie Ma and
submission deadline 28 Feb 2027 | 3 articles | Viewed by 1268 | Submission Open
Keywords: nanoparticle drug delivery; precision medicine; stem cell; proteomic and lipidomic profiling; novel therapeutic strategies; regenerative medicine; biologic drug development; IND submission
(This special issue belongs to the Section Molecular Medicine)
Ion Channels and Transporters in Immune Function and Inflammatory Disease
edited by Liang Hong and Lu Zhang
submission deadline 28 Feb 2027 | 1 articles | Viewed by 989 | Submission Open
Keywords: ion channel; immune regulation; electrophysiology; inflammation
(This special issue belongs to the Section Molecular Medicine)
Nutrition, Metabolism, and Obesity: Novel Strategies and Molecular Mechanisms—Future Perspectives, 2nd Edition
edited by Marion Korach-André
submission deadline 28 Feb 2027 | 1 articles | Viewed by 926 | Submission Open
Keywords: diet; nutrients; obesity; inflammation; fat; glucose intolerance; insulin resistance; fatty liver disease; metabolic syndrome
(This special issue belongs to the Section Molecular Medicine)
Natural Products Beyond Boundaries: Multidirectional Perspectives on Discovery, Bioactivity, Nanotechnology, and Industrial Applications submission deadline 28 Feb 2027 | 1 articles | Viewed by 823 | Submission Open
Keywords: natural products; phytochemicals; nanotechnology; bioactivity; industrial applications
(This special issue belongs to the Section Natural and Bio-derived Molecules)
Metabolic and Signaling Networks in Therapy Resistance
edited by and Lei Zhao
submission deadline 28 Feb 2027 | 1 articles | Viewed by 800 | Submission Open
Keywords: therapeutic resistance; metabolic reprogramming; systems biology; signaling networks
(This special issue belongs to the Section Molecular Medicine)
Extracellular Matrix Components and Glycobiology in Cancer: From Mechanisms to Therapeutic Targeting submission deadline 28 Feb 2027 | 1 articles | Viewed by 792 | Submission Open
Keywords: extracellular matrix; glycobiology; glycoconjugates; proteoglycans; tumor microenvironment
(This special issue belongs to the Section Molecular Medicine)
Detection of Cell-Associated Biomolecules
edited by
submission deadline 28 Feb 2027 | 1 articles | Viewed by 783 | Submission Open
Keywords: cell-associated biomolecules; detection technologies; subcellular localization; quantification; biomolecular complexes; signaling pathways; flow cytometry; single-cell analysis; imaging techniques
(This special issue belongs to the Section Molecular Biomarkers)
Advances in Cellular and Molecular Mechanisms in Immuno-Oncology and Onco-Hematology: 2nd Edition
edited by
submission deadline 28 Feb 2027 | 1 articles | Viewed by 765 | Submission Open
Keywords: cancer immunotherapy; inhibitory immune checkpoints; CAR T cells; tumor immune evasion; cancer target therapy
(This special issue belongs to the Section Cellular Biochemistry)
Tracking Aging and Stress: Omics-Based Insights into Physiology and Pathology submission deadline 28 Feb 2027 | 1 articles | Viewed by 736 | Submission Open
Keywords: genetic proteomic; lipidomic metabolomic; aging senescence; neurodegeneration; cellular stress
(This special issue belongs to the Section Biological Factors)
Molecular Motors in Muscle: From Single Molecules to Tissue Function
edited by
submission deadline 28 Feb 2027 | 1 articles | Viewed by 582 | Submission Open
Keywords: molecular motors; muscle mechanics; motor protein energetics; cytoskeletal dynamics; single-molecule biophysics
(This special issue belongs to the Section Molecular Biophysics: Structure, Dynamics, and Function)
Molecular Basis and Translational Research in Metabolic Myopathies: A Themed Issue in Honor of Professor Corrado Angelini, 2nd Edition submission deadline 28 Feb 2027 | Viewed by 549 | Submission Open
Keywords: metabolic myopathies; lipid metabolism; glycogen metabolism; genetic diseases; treatments; lipid storage myopathies; glycogen storage myopathies; lysosomal storage myopathies
(This special issue belongs to the Section Molecular Biology)
Protein Structure Prediction in Drug Discovery, 3rd Edition submission deadline 28 Feb 2027 | Viewed by 488 | Submission Open
Keywords: protein structure prediction; drug design; docking; virtual screening; drug discovery; machine learning; alphafold
(This special issue belongs to the Section Bioinformatics and Systems Biology)
Design and Applications of 3D Bioprinting
edited by and
submission deadline 28 Feb 2027 | Viewed by 363 | Submission Open
Keywords: 3D bioprinting; biofabrication; tissue engineering; regenerative medicine; smart biomaterials; scaffold design; organ models; personalized therapeutics; biomedical additive manufacturing; translational bioprinting
(This special issue belongs to the Section Bio-Engineered Materials)
White Matter Injury and Neurovascular Dysfunction in Neurological Disorders
edited by
submission deadline 28 Feb 2027 | 1 articles | Viewed by 315 | Submission Open
Keywords: white matter injury, remyelination, neurovascular dysfunction; neurovascular unit; ischemic stroke; neurodegeneration; blood–brain barrier; cellular mechanisms; molecular pathways; vascular cognitive impairment; Alzheimer's disease
(This special issue belongs to the Section Molecular Medicine)
Novel Insights into Epithelial Mesenchymal Transition (EMT) in Cancer
edited by
submission deadline 28 Feb 2027 | 1 articles | Viewed by 311 | Submission Open
Keywords: EMT; epithelial–mesenchymal plasticity; hybrid E/M states; single-cell; spatial transcriptomics/proteomics; multiplex IHC/IF; RNA in situ; CTCs; ctDNA; radiomics; computational pathology; immune evasion; therapy resistance; metastasis; biomarkers; reporting standards; reproducibility; clinical translation
(This special issue belongs to the Section Molecular Medicine)
Nanomaterials and Their Applications in Biomedicine—2nd Edition
edited by
submission deadline 28 Feb 2027 | Viewed by 258 | Submission Open
Keywords: photothermal and photodynamic therapies and tumor ablation strategies; theranostics and image-guided drug delivery; biosensors, including surface-enhanced Raman scattering and metal-enhanced fluorescence; biosensors; point-of-care diagnostics and lateral-flow tests; controlled drug delivery, including delivery of RNA/DNA and other biologics; additive manufacturing and 3D/4D printing applications; antimicrobials; cell therapeutics and tissue regeneration
(This special issue belongs to the Section Bio-Engineered Materials)
Molecular Regulation of Biomaterials and Engineering for Skeletal and Cartilage Regeneration
edited by
submission deadline 28 Feb 2027 | Viewed by 255 | Submission Open
Keywords: biomaterials; molecular regulation; skeletal regeneration; cartilage regeneration; cell–matrix interaction; osteogenesis and chondrogenesis; mechanotransduction; immunomodulation; translational regenerative medicine
(This special issue belongs to the Section Bio-Engineered Materials)
When Molecules Meet Light: Advances in Photodynamic Therapy and Imaging submission deadline 28 Feb 2027 | Viewed by 141 | Submission Open
Keywords: molecules; light; photodynamic therapy; imaging
(This special issue belongs to the Section Molecular Medicine)
Cytogenetics, Molecular Diagnostics and Biomarkers in Hematologic Malignancies
edited by Changqing Xia and
submission deadline 28 Feb 2027 | Viewed by 112 | Submission Open
Keywords: cytogenomics; cytogenetics; molecular biomarkers; leukemia; lymphoma; multiple myeloma; diagnosis; prognosis; targeted therapies; precision medicine
(This special issue belongs to the Section Molecular Biomarkers)
NFAT Transcription Factors in Immunity and Disease : A Themed Issue in Honor of Prof. Edgar Serfling
edited by
submission deadline 28 Feb 2027 | Viewed by 85 | Submission Open
Keywords: NFAT transcription factors; T-cell activation; immune regulation; transcriptional control; inflammation; cancer immunology; signal transduction; immunotherapy; calcineurin signaling; transplantation; transplant immunology; immunosuppression; targeted therapy
(This special issue belongs to the Section Cellular Biochemistry)
Chronic Heart Failure: From Molecular Mechanisms to Therapies Strategies: 2nd Edition submission deadline 28 Feb 2027 | Viewed by 58 | Submission Open
Keywords: chronic heart failure; pathophysiology; comorbidities; new therapies; molecular pathways
(This special issue belongs to the Section Molecular Medicine)
Iron Metabolism and the Biophysical Landscape of Cells submission deadline 28 Feb 2027 | Viewed by 20 | Submission Open
Keywords: Fe metabolism; Fe regulation proteins; Fe quantification; Fe dysregulation; Fe transport; Fe recycling; Fe uptake; ferroptosis
(This special issue belongs to the Section Molecular Biology)
Emerging Bioactives from Underexplored Botanical Sources and By-Products for Food Applications
edited by Suelen Pereira Ruiz Herrig, Zilda Cristiani Gazim and Beatriz Cervejeira Bolanho Barros
submission deadline 1 Mar 2027 | Viewed by 338 | Submission Open
Keywords: botanical bioactives; by-products; natural food additives; green extraction
(This special issue belongs to the Section Natural and Bio-derived Molecules)
The Impact of Obesity, Ethnicity, and Genetic Susceptibility on Beta Cell Function
edited by Joseph Proietto
submission deadline 12 Mar 2027 | Viewed by 79 | Submission Open
Keywords: obesity-induced diabetes; beta cell function; diabetes complications; susceptibility; genetics
(This special issue belongs to the Section Biological Factors)
Molecular Mechanisms and Emerging Therapies for Diabetic Cardiomyopathy submission deadline 15 Mar 2027 | Viewed by 104 | Submission Open
Keywords: diabetic cardiomyopathy; diabetes-related cardiac dysfunction; cardiac remodeling; molecular mechanisms; emerging therapies; cardiometabolic disease
(This special issue belongs to the Section Molecular Medicine)
Dynamic Remodeling of the 3D Genome in Development and Diseases
edited by
submission deadline 18 Mar 2027 | Viewed by 90 | Submission Open
Keywords: 3D genome organization; cell fate specification; disease pathogenesis; topologically associating domains (TADs); enhancer–promoter interactions; gene expression regulation
(This special issue belongs to the Section Molecular Reproduction)
Biomarkers in Musculoskeletal and Orthopedic Disorders
edited by
submission deadline 20 Mar 2027 | 2 articles | Viewed by 1855 | Submission Open
Keywords: musculo-skeletal pathologies; orthopaedic infections; synovial fluid analysis
(This special issue belongs to the Section Molecular Biomarkers)
Effects of Microvascular Dysfunction on Neurological and Cardiovascular Diseases
edited by Adjanie Patabendige and
submission deadline 20 Mar 2027 | Viewed by 35 | Submission Open
Keywords: microvascular dysfunction; heart-brain axis; neurovascular interface; blood–brain barrier; stroke; dementia; small vessel disease; hypertension; atrial fibrillation; heart failure
(This special issue belongs to the Section Molecular Medicine)
Signal Transduction and Pathway Regulation in Cancer submission deadline 25 Mar 2027 | 5 articles | Viewed by 4536 | Submission Open
Keywords: signal transduction; pathway modulation; targeted treatment strategies; cancer treatment; drug resistance; cancer diagnosis; cancer prognosis
(This special issue belongs to the Section Molecular Biology)
Computational Analysis and Conformational Modeling for Protein Structure and Interaction: Second Edition
edited by and
submission deadline 26 Mar 2027 | 3 articles | Viewed by 1617 | Submission Open
Keywords: protein structure prediction; drug discovery targeting proteins; structural bioinformatics; molecular dynamics simulations; protein–protein interactions; protein–ligand binding; conformational dynamics; molecular docking studies
(This special issue belongs to the Section Biomacromolecules: Proteins, Nucleic Acids and Carbohydrates)
Endocrine Regulation of Reproductive Tissues: From Molecular Mechanisms to Therapies submission deadline 26 Mar 2027 | Viewed by 533 | Submission Open
Keywords: hormone signaling; reproductive physiology; steroid receptors; infertility; endocrine disruptors; epigenetic regulation; gonadal steroids; hormone-dependent cancers; therapeutic targeting; gametogenesis
(This special issue belongs to the Section Biological Factors)
Roles of Epigenetics in Plant Defense submission deadline 28 Mar 2027 | Viewed by 78 | Submission Open
Keywords: plant defense; epigenetics; epitranscriptomics; non-coding RNAs; chromatin remodeling; RNA modifications; plant–pathogen interactions; defense priming; CRISPR epigenome editing; genome wide; multi-omics; disease-resistant crops; artificial intelligence (AI); systemic acquired resistance (SAR); induced systemic resistance (ISR); pattern-triggered immunity (PTI); effector-triggered immunity (ETI)
(This special issue belongs to the Section Molecular Genetics)
Molecular Factors Involved in Healthy and Diseased States of Skeletal Muscle: Overview and Perspectives submission deadline 30 Mar 2027 | 3 articles | Viewed by 4107 | Submission Open
Keywords: skeletal muscle; ageing; muscle physiology; muscle-multiorgan crosstalk; muscle health; muscle atrophy; molecular factors; sedentariness; exercise
(This special issue belongs to the Section Biological Factors)
Pathogenesis and Targeted Therapy of Neurodegenerative Diseases submission deadline 31 Mar 2027 | 4 articles | Viewed by 10576 | Submission Open
Keywords: neurodegeneration; neurodegenerative diseases; targeted therapy; molecular mechanisms; disease-modifying treatments
(This special issue belongs to the Section Molecular Medicine)
Endocrine, Immune and Molecular Biomarkers in Pain and Psychosomatic Disorders: Bridging Mechanisms and Medical Application submission deadline 31 Mar 2027 | 3 articles | Viewed by 5215 | Submission Open
Keywords: personalized pain medicine; systems biology of pain; neuroendocrine regulation; molecular biomarkers; psychosomatic disorders
(This special issue belongs to the Section Biological Factors)
Innate Immunity and Inflammation: From Molecular Mechanisms to Therapeutic Applications
edited by and Anthea Miller
submission deadline 31 Mar 2027 | 2 articles | Viewed by 4285 | Submission Open
Keywords: inflammation; innate immunity; therapeutic targets; immune signaling pathways; pattern-recognition receptors (PRRs)
(This special issue belongs to the Section Molecular Medicine)
Recent Advances in Laccases and Laccase-Based Bioproducts: 2nd Edition submission deadline 31 Mar 2027 | 3 articles | Viewed by 3963 | Submission Open
Keywords: laccase; application; heterologous expression; bioproducts; laccase engineering
(This special issue belongs to the Section Enzymology)
Nitric Oxide and Reactive Species in Plant Physiology and Pathology
edited by
submission deadline 31 Mar 2027 | 2 articles | Viewed by 3899 | Submission Open
Keywords: nitric oxide; reactive oxygen species; reactive sulfur species; redox signaling; S-nitrosylation; plant stress tolerance; antioxidant systems; phytohormones; metabolic regulation
(This special issue belongs to the Section Biological Factors)
Back to TopTop