Ion Channels and Transporters in Immune Function and Inflammatory Disease

A special issue of Biomolecules (ISSN 2218-273X). This special issue belongs to the section "Molecular Medicine".

Deadline for manuscript submissions: 28 February 2027 | Viewed by 62

Special Issue Editors


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Guest Editor
Department of Medicine, Division of Cardiology, University of Illinois at Chicago, Chicago, IL, USA
Interests: cardiology; proton channel; macrophages; EndMT; autophagy
Special Issues, Collections and Topics in MDPI journals

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Guest Editor Assistant
Department of Medicine, Division of Cardiology, University of Illinois at Chicago, Chicago, IL, USA
Interests: cardiology; proton channel; macrophages; EndMT; autophagy
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Ion channels and transporters play essential roles in regulating immune cell activation and signalling, coordinating a wide range of cellular processes through the control of ionic homeostasis and membrane potential. These transmembrane proteins critically influence immune responses, including cytokine production, antigen presentation, phagocytosis, and the initiation and resolution of inflammation. In recent years, accumulating evidence has highlighted their essential roles in both innate and adaptive immunity.

Importantly, dysregulation of ion channels and transporters has been increasingly linked to the pathogenesis of numerous inflammatory and immune-mediated diseases, such as autoimmune disorders, cardiovascular inflammation, and infectious diseases. Advances in molecular biology, electrophysiology, and disease modelling have significantly deepened our understanding of how these proteins contribute to immune regulation and disease progression, while also revealing their potential as novel therapeutic targets.

This Special Issue, entitled “Ion Channels and Transporters in Immune Function and Inflammatory Disease”, aims to bring together the latest research and comprehensive reviews in this rapidly evolving field. We welcome contributions that explore molecular mechanisms, physiological and pathological functions, and innovative therapeutic strategies targeting ion channels and transporters in the immune and inflammatory systems. Studies addressing emerging technologies, translational approaches, and interdisciplinary perspectives are particularly encouraged.

Both original research articles and review papers providing novel insights or comprehensive overviews are warmly invited.

Dr. Liang Hong
Guest Editor

Dr. Lu Zhang
Guest Editor Assistant

Manuscript Submission Information

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Keywords

  • ion channel
  • immune regulation
  • electrophysiology
  • inflammation

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Published Papers

This special issue is now open for submission.
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