Wound Repair and Regeneration: From Molecular and Cellular Mechanisms to New Approaches
A special issue of Biomolecules (ISSN 2218-273X). This special issue belongs to the section "Molecular Medicine".
Deadline for manuscript submissions: 20 July 2026 | Viewed by 1817
Special Issue Editor
Interests: wound healing; cell signaling; honeybee products; natural products; honey; confocal microscopy; Ca2+ signaling; oxidative stress
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
We are pleased to invite you to contribute to this Special Issue of Biomolecules, entitled “Wound Repair and Regeneration: From Molecular and Cellular Mechanisms to New Approaches.”
Wound healing is a complex, multistep biological process crucial for the restoration of the skin barrier and maintenance of tissue integrity following injury. This highly orchestrated cascade has some overlapping phases, namely hemostasis, inflammation, proliferation, and remodeling, each controlled by interactions between many cell types, such as keratinocytes, fibroblasts, endothelial cells, and immune cells, through complex networks of various signaling molecules.
This process often proceeds toward suboptimal outcomes, either to chronic, non-healing wounds—a huge burden on health care systems—or to excessive fibrosis and scarring. A more complete elucidation of the detailed molecular and cellular mechanisms that either allow or prohibit the transition from normal repair to pathologic states—or dictate successful tissue regeneration, as observed in lower vertebrates—remains an important challenge. It is of the highest priority, since the ultimate goal is not only to establish effective treatments for chronic wounds but also to continue in the development of strategies in regenerative medicine and tissue engineering.
This Special Issue aims to collect a suite of state-of-the-art original research articles and comprehensive reviews that shed light on the sophisticated processes underlying wound repair and tissue regeneration.
It aims to provide a focused platform for disseminating high-quality work that bridges the gap from basic science discoveries—such as novel cellular pathways and biomechanical cues—to their translational applications, including smart biomaterials and cell-based therapies.
This Special Issue falls particularly within the mission of Biomolecules, which is to publish high-impact research and present a timely synthesis of progress in this fast-moving area. We expect a collection of articles that will be a valued resource for researchers, clinicians, and industry professionals. Original research articles and reviews will be welcome in this Special Issue. Submissions focused on basic biology, pathophysiology, and novel therapeutic approaches of wound healing are invited.
We look forward to hearing from you.
Dr. Elia Ranzato
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biomolecules is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- wound repair
- tissue regeneration
- molecular mechanisms
- cellular mechanisms
- chronic wounds
- fibrosis/scarring
- biomaterials
- stem cells
- translational therapies
Benefits of Publishing in a Special Issue
- Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
- Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
- Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
- External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
- Reprint: MDPI Books provides the opportunity to republish successful Special Issues in book format, both online and in print.
Further information on MDPI's Special Issue policies can be found here.
