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Biology publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Gut Microbiome in Health and Disease (3rd Edition)

edited by

Hao Zhong

and

Fengqin Feng

submission deadline 30 Sep 2026 | Viewed by 101 | Submission Open

Keywords: gut microbiota; ‘ gut– X’ axis; dysbiosis; food nutrition; metabolites; type 2 diabetes mellitus; gut health; immunity

(This special issue belongs to the Section Microbiology)

Molecular Mechanisms of Retina Development and Degeneration

edited by

Hélène Léger

submission deadline 30 Sep 2026 | Viewed by 77 | Submission Open

Keywords: retina; retinal development; retinal degeneration; molecular mechanisms; signaling pathways; genetic regulation; epigenetics; neuronal and glial interactions; neuroinflammation

(This special issue belongs to the Section Biochemistry and Molecular Biology)

The Molecular and Cellular Mechanisms of Lung Injury and Recovery

edited by Weiguo Chen, HongLong Ji and Ibra S. Fancher

submission deadline 30 Sep 2026 | Viewed by 72 | Submission Open

Keywords: acute lung injury; chronic lung injury; ARDS; fibrosis; allergy; mechanisms; therapy; infection; inflammation; endothelial barrier

(This special issue belongs to the Section Biochemistry and Molecular Biology)

Pathogenic Mechanisms Involved in Development and Progression of ROS-Associated Diseases

edited by

Hye-Jin Park

submission deadline 30 Sep 2026 | Viewed by 49 | Submission Open

Keywords: Reactive Oxygen Species (ROS); oxidative stress; pathogenic mechanisms; disease progression; mitochondrial dysfunction; inflammation and immune regulation; redox biology; molecular signaling pathways; antioxidants and therapeutics; comparative medicine; One Health; translational research

(This special issue belongs to the Section Biochemistry and Molecular Biology)

Innovative Approaches to Rice Crop Production Under Environmental Stresses

edited by

Chanakan Prom-u-thai

submission deadline 30 Sep 2026 | Viewed by 49 | Submission Open

Keywords: abiotic stress; environmental stress response; stress adaptation; DNA damage and repair; functional genomics; plant physiology; biofortification

(This special issue belongs to the Section Genetics and Genomics)

Ecological Interactions and Adaptive Strategies in Wildlife

edited by

Motti Charter

submission deadline 30 Sep 2026 | Viewed by 15 | Submission Open

Keywords: biological pest control; predator– prey dynamics; avian reproductive ecology; evolutionary traits; human– wildlife coexistence; invasive species impacts; artificial nest ecology; ecosystem

(This special issue belongs to the Section Conservation Biology and Biodiversity)

Genetics and Epigenetics of Neurological Disorders

edited by

Milena Janković

submission deadline 30 Sep 2026 | Viewed by 13 | Submission Open

Keywords: neurological disorders; neurogenetics; genomics; epigenomics; DNA methylation; precision medicine

(This special issue belongs to the Section Neuroscience)

Pollination Biology: 2nd Edition

edited by

Yu Gao

and

Bartosz Płachno

submission deadline 1 Oct 2026 | Viewed by 87 | Submission Open

Keywords: conservation biology; insect diversity; pollinator-plant interactions; ecosystem service; pollinating insect; flower; bee

(This special issue belongs to the Section Ecology)

Semaphorins as Drivers of Inflammatory Disease: Setting Immune Cells in Motion

edited by

Tiago Granja

submission deadline 3 Oct 2026 | Viewed by 45 | Submission Open

Keywords: semaphorins; inflammation; neuronal guidance proteins; soluble guidance cues; cell motility; cytoskeletal dynamics; extracellular matrix

(This special issue belongs to the Section Immunology)

Multi-omics Approaches in Agricultural Crops to Unravel Responses to Environmental Stresses and Advance Sustainable Agriculture

edited by

Vito Butardo

submission deadline 30 Oct 2026 | 2 articles | Viewed by 4983 | Submission Open

Keywords: plant functional genomics; environmental stress; climate change; crop yield; crop quality; nutritional properties; omics approaches; genomics; transcriptomics; proteomics; metabolomics; epigenomics; phenomics; stress-tolerant crops; breeding strategies; data integration; systems biology; sustainable agriculture; underutilized crops; orphan crops; beneficial microorganisms

(This special issue belongs to the Section Plant Science)

Pathophysiology of Hearing Loss

edited by Charles E. Bishop

submission deadline 30 Oct 2026 | 2 articles | Viewed by 905 | Submission Open

Keywords: hearing loss; cochlea; noise; deafness genes; cell death; hair cells; inner ear; biotoxicity; metabolic risk; gene mutation; physiology and pathophysiology; animal models; biomarkers and molecular mechanisms

(This special issue belongs to the Section Physiology)

Molecular, Biophysical, and Neurophysiological Mechanisms Underlying Magnetoreception

edited by

Weidong Pan

and

Guijun Wan

submission deadline 30 Oct 2026 | Viewed by 138 | Submission Open

Keywords: earth magnetic field; magnetosensing; magnetite; radical pair; orientation; navigation; magnetic receptor; electroreceptor; neurophysiology

Fatty Acid Metabolism and Inflammation

edited by

Mi-hee Park

submission deadline 30 Oct 2026 | Viewed by 68 | Submission Open

Keywords: fatty acid metabolism; metabolic dysfunction; mitochondrial impairment; oxidative stress; glucose metabolism; lipid metabolism; Immune modulation; Inflammation; biomarkers

(This special issue belongs to the Section Physiology)

Animal Virus–Host Interactions and Cross-Species Dynamics

edited by

Anan Jongkaewwattana

and

Thanathom Chailangkarn

submission deadline 30 Oct 2026 | Viewed by 60 | Submission Open

Keywords: animal viruses; zoonosis; pathogenesis; host immunity; vaccines; antivirals; host– pathogen interaction; One Health; veterinary virology

(This special issue belongs to the Section Infection Biology)

Advances in Zebrafish as an Experimental Model: From Husbandry to Cutting-Edge Applications

edited by Rosario Moyano-Salvago,

Rafael Mora Medina

and

Nahúm Ayala-Soldado

submission deadline 30 Oct 2026 | Viewed by 27 | Submission Open

Keywords: zebrafish; experimental model; developmental biology; genetics; gene editing; transgenesis; toxicology; regeneration; animal welfare; biomedical research

(This special issue belongs to the Section Zoology)

Immunosenescence and Its Modification by Interventions

edited by

Andreas Meryk

and Luca Pangrazzi

submission deadline 31 Oct 2026 | 1 articles | Viewed by 5821 | Submission Open

Keywords: immunosenescence; aging immune system; inflammaging; vaccine efficacy in elderly; nutritional immunomodulation; exercise and immunity; senolytic therapies; T-cell exhaustion; thymic rejuvenation; age-related diseases

(This special issue belongs to the Section Immunology)

Mitochondria and Cardiovascular Diseases

edited by Qingxun Hu

submission deadline 31 Oct 2026 | 1 articles | Viewed by 2585 | Submission Open

Keywords: cardiovascular diseases; mitochondria; pathophysiology; cardiology; cell metabolism; animal models; epigenetics; redox biology

(This special issue belongs to the Section Physiology)

Transcriptional Regulation in Eukaryotes

edited by Anil Kumar Panigrahi

submission deadline 31 Oct 2026 | Viewed by 501 | Submission Open

Keywords: transcription factors (TFs); transcriptional coregulators; RNA polymerase II; chromatin modifications and remodeling; enhancers; silencers; non-coding RNAs; 3D chromatin architecture; multi-omics integration; single-cell technologies

(This special issue belongs to the Section Genetics and Genomics)

Advances in Plant Multi-Omics

edited by

Xiuzhang Li

, Zhonglong Guo and Xuekai Wei

submission deadline 31 Oct 2026 | 1 articles | Viewed by 430 | Submission Open

Keywords: multi-omics integration; plant systems biology; high-throughput sequencing; bioinformatics integration; stress response

(This special issue belongs to the Section Plant Science)

Brain Organoids: Construction, Analysis, and Application

edited by

Jonghun Kim

submission deadline 31 Oct 2026 | Viewed by 194 | Submission Open

Keywords: brain organoids; iPSCs; neurodevelopmental disorders; region-specific organoids; functional neuronal analysis

Decoding RNA Modifications in Cancer Biology

edited by Yutao Zhao

submission deadline 31 Oct 2026 | Viewed by 114 | Submission Open

Keywords: RNA modifications; epitranscriptomics; gene regulation; RNA biology; post-transcriptional regulation; N6-methyladenosine (m6A); pseudouridine (Ψ )

(This special issue belongs to the Section Cancer Biology)

Current Advances in Cancer Genomics

edited by

Yuanxiang Li

submission deadline 31 Oct 2026 | Viewed by 76 | Submission Open

Keywords: cancer genomics; tumor heterogeneity; epigenomics; single-cell sequencing; multi-omics; genomic biomarkers; precision oncology; computational genomics; non-coding RNA; drug resistance

(This special issue belongs to the Section Cancer Biology)

Pathogenesis and Immune Evasion of Mycobacteria in Mammals

edited by Laura Klepp and Federico Carlos Blanco

submission deadline 31 Oct 2026 | Viewed by 73 | Submission Open

Keywords: mycobacteria; pathogenesis; immune evasion; host– pathogen interactions; latency; zoonotic transmission; comparative immunology; vaccine development; host-directed therapies

(This special issue belongs to the Section Immunology)

Molecular Mechanisms of AHPND: From Pathogen Virulence to Host Immunity

edited by

Sonia A. Soto-Rodriguez

submission deadline 31 Oct 2026 | Viewed by 38 | Submission Open

Keywords: AHPND; Vibrio; pathogenesis; host immunity; shrimp disease; aquaculture; virulence mechanisms; omics

(This special issue belongs to the Section Biochemistry and Molecular Biology)

Research Advances on Biology and Genetics of Bees

edited by

Jiaxing Huang

and

Guiling Ding

submission deadline 31 Oct 2026 | Viewed by 7 | Submission Open

Keywords: bee biology; pollination ecology; environmental stressors; bee genomics and omics; bee health and conservation; foraging behavior and social organization

(This special issue belongs to the Section Zoology)

Genetics and Evolutionary Biology of Aquatic Organisms

edited by

Qianhong Gu

and Liang Guo

submission deadline 15 Nov 2026 | 3 articles | Viewed by 1158 | Submission Open

Keywords: population genetics; conservation genetics; biodiversity; comparative genomics; polyploidization; rapid adaptation; population genetic divergence; thermal tolerance; hypoxia adaptation; deep-sea pressure adaptation; convergent evolution; molecular clock; phylogeography; population genetic structure; divergence time; inbreeding depression; genetic diversity; genomic selection; genome assembly; transcriptomics; population genomics

(This special issue belongs to the Section Evolutionary Biology)

Erythrocytes in Human Life—Functions Beyond Oxygen Transport

edited by

Vesna Ilic

and

Ivana Drvenica

submission deadline 15 Nov 2026 | Viewed by 155 | Submission Open

Keywords: erythrocytes in physiological processes; erythrocytes in disease pathophysiology; erythrocyte biomechanics; erythrocyte imaging; erythrocyte membrane; erythrocyte metabolism; haemoglobin; immune modulation; redox homeostasis

(This special issue belongs to the Section Cell Biology)

Stem Cell Stress Responses: Mechanisms, Models, and Implications

edited by Taku Kaitsuka

submission deadline 30 Nov 2026 | Viewed by 92 | Submission Open

Keywords: stem cells; stress response; differentiation; heat stress; hypoxic stress; oxidative stress; mechanical stress; proteotoxic stress; membrane protein; stress-inducible transcription factor

(This special issue belongs to the Section Cell Biology)

Ecological Dynamics of Vector-Borne Pathogens: From Hosts to Vectors

edited by

Sofia Ferreira Anastácio

Joana Ferrolho Gibson

and Hugo C. R. Vilhena

submission deadline 30 Nov 2026 | Viewed by 87 | Submission Open

Keywords: vector-borne pathogens; host– vector interactions; climate change; disease emergence

(This special issue belongs to the Section Microbiology)

Neurodegeneration: Pathways and Mechanisms

edited by

Ferdinando Franzoni

and

Giorgia Scarfò

submission deadline 30 Nov 2026 | Viewed by 39 | Submission Open

Keywords: inflammation; oxidative stress; apoptosis; exercise; diet; cellular pathways

(This special issue belongs to the Section Neuroscience)

New Perspectives of Immunity Against SARS-CoV-2

edited by

Jorge A. Soto

and

Felipe Melo-González

submission deadline 30 Nov 2026 | Viewed by 8 | Submission Open

Keywords: innate and adaptive immune responses; viral immune evasion; mucosal and systemic immunity; vaccine-induced protection; host– pathogen interactions; immunomodulation and antiviral strategies

(This special issue belongs to the Section Immunology)

The 1st International Online Conference on Biology—“Across Levels of the Biological Organization” (Biology 2025)

edited by

Andrés Moya

submission deadline 30 Nov 2026 | Viewed by 2 | Submission Open

Keywords: biological complexity; climate change; global biodiversity; host-parasite interactions; plant adaptations

Recent Advances in Understanding Systemic Lupus Erythematosus Pathogenesis

edited by Rohit Upadhyay

submission deadline 15 Dec 2026 | Viewed by 302 | Submission Open

Keywords: systemic lupus erythematosus (SLE); autoimmunity; immune dysregulation; B and T cell biology; interferon signaling; autoantibodies; epigenetics; biomarkers; therapeutic targets; systems immunology

(This special issue belongs to the Section Medical Biology)

Bacterial Secretion Systems: Mechanisms, Regulation, and Their Roles in Microbe–Microbe and Microbe–Host Interactions

edited by

Lingfang Zhu

submission deadline 15 Dec 2026 | Viewed by 64 | Submission Open

Keywords: secretion system; pathogenicity; quorum sensing; expression and regulation; transcriptomics; environmental adaptability; microbial interaction mechanism

(This special issue belongs to the Section Microbiology)

Impacts of Climate Change on Terrestrial Carbon Cycling and Biodiversity Across Spatial and Temporal Scales

edited by

Nophea Sasaki

and

Takuji W. Tsusaka

submission deadline 21 Dec 2026 | 2 articles | Viewed by 2047 | Submission Open

Keywords: climate change; terrestrial carbon cycling; biodiversity; spatial and temporal scales; ecosystem resilience; UN CBD; UN Decade on Ecosystem Restoration; responsible business; nature-based solutions; sustainable development

(This special issue belongs to the Section Conservation Biology and Biodiversity)

Advances in Tropical and Subtropical Plant Ecology and Physiology

edited by Naysa Flávia Ferreira Do Nascimento and Edna Ursulino Alves

submission deadline 30 Dec 2026 | 1 articles | Viewed by 496 | Submission Open

Keywords: tropical plants; plant ecology; plant physiology; environmental adaptations; phenotypic diversity; climate change; biodiversity conservation; sustainable management

(This special issue belongs to the Section Plant Science)

Biology, Ecology and Management of Aquatic Macrophytes and Algae—2nd Edition

edited by

Jinlin Liu

Wei Liu

and Shuang Zhao

submission deadline 31 Dec 2026 | 4 articles | Viewed by 4862 | Submission Open

Keywords: aquatic macrophytes and algae; ecological planning and management; harmful algal blooms and control; biological resources and environment; aquatic ecosystem stability; ecological restoration; biodiversity; plant physiology; biomarkers; symbiotic microorganisms

Aquatic Economic Animal Breeding and Healthy Farming (2nd Edition)

edited by Yude Wang and Shengwei Luo

submission deadline 31 Dec 2026 | 1 articles | Viewed by 532 | Submission Open

Keywords: rice– fish; fish; and aquaculture; hybridization and genetic breeding; nutrient additive and requirement; physiology and immune response; disease control; pathogenesis research; probiotic identification and function; transcriptomics; proteomics; metabonomics

(This special issue belongs to the Section Zoology)

Cellular Senescence in Development, Regeneration, Aging, and Cancer

edited by

Selim Chaib

submission deadline 31 Dec 2026 | Viewed by 477 | Submission Open

Keywords: cellular senescence; aging; cancer; obesity; metabolism; geroscience; age-related diseases; SASP; senolytics; biomarkers

Advances in Biomechanics in Physiology and Pathology

edited by Chi Wei Ong and

Milan Toma

submission deadline 31 Dec 2026 | Viewed by 147 | Submission Open

Keywords: biomechanics; mechanics; extracellular matrix; cellular mechanics; tissue remodeling; developmental biomechanics; computational modeling; bioimaging; engineered microenvironments; artificial intelligence; machine learning

(This special issue belongs to the Section Biophysics)

Advances in Biological Research into Shrimps, Crabs and Lobsters (2nd Edition)

edited by Lutz Auerswald

submission deadline 31 Dec 2026 | Viewed by 88 | Submission Open

Keywords: Crustacea; Decapoda; biology; fishery; aquaculture; ecology; bio-compounds; seafood; physiology; immunology; genetics

(This special issue belongs to the Section Zoology)

Feature Papers on Toxicology

edited by

Hui Xu

submission deadline 31 Dec 2026 | Viewed by 63 | Submission Open

Keywords: toxicology; cellular toxicity; organ toxicity; biomarkers; molecular mechanisms; in vitro models; in vivo models; risk assessment; environmental exposures; chemical toxicology

(This special issue belongs to the Section Toxicology)

From Cell Division to Systemic Dysregulation: Genetic Mechanisms and Biomarkers in Civilization Diseases

edited by

Robert Zdanowski

and

Agata Borkowska

submission deadline 31 Dec 2026 | Viewed by 56 | Submission Open

Keywords: cell cycle regulation; genetic and epigenetic mechanisms; cellular senescence; oxidative stress; inflammation; molecular biomarkers; neurodegeneration; tumor microenvironment; metabolic and cardiovascular diseases

(This special issue belongs to the Section Cell Biology)

Molecular Insights into Malignant Cutaneous Adnexal Neoplasms

edited by

Albert Alhatem

and Rosalynn M. Nazarian

submission deadline 31 Dec 2026 | Viewed by 40 | Submission Open

Keywords: malignant adnexal neoplasms; sebaceous carcinoma; hidradenocarcinoma; malignant spiradenoma; trichoblastic carcinoma; molecular mechanisms; signal transduction pathways; tumor microenvironment; epigenetics; genomic profiling

(This special issue belongs to the Section Cancer Biology)

Metabolic and Stress Responses in Aquatic Animals (2nd Edition)

edited by

Marcelino Herrera

, Laura Fernández-Alacid and

Ignacio Ruiz-Jarabo

submission deadline 31 Dec 2026 | Viewed by 39 | Submission Open

Keywords: stress; metabolism; animal welfare; aquaculture; cephalopods; fish; molluscs; crustaceans; aquatic animals; animal physiology

(This special issue belongs to the Section Zoology)

Novel Dynamics and Mechanisms of Stromal–Leukocyte Interactions in Tissue Inflammation, Immunity and Healing

edited by Matthias Friedrich, Pablo Céspedes and Mathilde Pohin

submission deadline 31 Dec 2026 | Viewed by 22 | Submission Open

Keywords: stromal– immune crosstalk; chronic inflammation; tissue repair and regeneration; single-cell omics; immunometabolism; fibrosis; spatial transcriptomics; immune tolerance; cytokine signaling; stromal niche immunology

(This special issue belongs to the Section Physiology)

Non-Coding RNA Research and Functional Insights

edited by

Zorana Dobrijević

and

Milos Brkusanin

submission deadline 31 Dec 2026 | Viewed by 20 | Submission Open

Keywords: non-coding RNA; microRNA; long non-coding RNA; circular RNA; gene expression regulation; biomarkers; epigenetics

(This special issue belongs to the Section Genetics and Genomics)

Biological Rhythms and Molecular Clockworks in Physiology and Pathology (2nd Edition)

edited by

Gianluigi Ubaldo Mazzoccoli

and

Marina Maria Bellet

submission deadline 31 Jan 2027 | Viewed by 75 | Submission Open

Keywords: biological rhythms; molecular clockworks; circadian timing system; circadian desynchrony; circadian disruption; chronopathology; chronopharmacology and chronotherapeutics; chronomedicine

Multi-Omics Data Integration in Complex Diseases (2nd Edition)

edited by

Min Zhao

and

Dario Di Silvestre

submission deadline 31 Jan 2027 | Viewed by 37 | Submission Open

Keywords: omics; data integration; computational biology; network analysis; artificial intelligence

(This special issue belongs to the Section Bioinformatics)

Congenital Craniofacial Bone Defects and Facial Clefts: Imaging, Morphology, and Developmental Insights from Museum Specimens

edited by

Helga Rehder

and

Stefan Tangl

submission deadline 30 Oct 2027 | Viewed by 28 | Submission Open

Keywords: craniofacial malformations and bone defects; facial clefts; agnathia-otocephaly complex; holoprosencephaly; encephaloceles; high resolution imaging techniques; micro-CT analysis; malformation syndromes; museum specimens; facial development

(This special issue belongs to the Section Developmental and Reproductive Biology)

Displaying special issue 301-350 on page 7 of 7.

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