From Cell Division to Systemic Dysregulation: Genetic Mechanisms and Biomarkers in Civilization Diseases
A special issue of Biology (ISSN 2079-7737). This special issue belongs to the section "Cell Biology".
Deadline for manuscript submissions: 31 December 2026 | Viewed by 1301
Special Issue Editors
Interests: regulatory lymphocytes; cell biology; immunotoxicology; clinical immunology; neuroimmunology; flow cytometry
Interests: cell and molecular biology; neurobiology; blood–brain barrier; cancer biology; senescence
Special Issue Information
Dear Colleagues,
Cell division and genetic regulation are fundamental processes that sustain life and maintain tissue homeostasis. The dysregulation of these mechanisms underlies the pathogenesis of a wide range of human disorders, from cancer and neurodegeneration to infectious diseases and diseases of civilization such as diabetes, obesity, and cardiovascular conditions. Increasing evidence highlights the role of genetic and epigenetic alterations, cellular senescence, and molecular biomarkers in the development and progression of these diseases. Understanding these complex interactions at the cellular and systemic levels is crucial in the advancement of diagnostics, prognostics, and targeted therapies.
We are pleased to invite you to contribute to this Special Issue, “From Cell Division to Systemic Dysregulation: Genetic Mechanisms and Biomarkers in Civilization Diseases”. We aim to showcase novel insights into molecular and cellular mechanisms, as well as translational research highlighting their clinical impact.
This Special Issue will explore how the dysregulation of fundamental genetic and cellular processes contributes to the onset and progression of complex human diseases, with a focus on diseases of civilization. Contributions will cover basic molecular mechanisms, biomarker discovery, and translational perspectives across infectious, neurological, oncological, and metabolic disorders.
This Special Issue will fit within the journal’s scope by addressing key areas of cell biology, genetics, molecular medicine, and biomarker research. By gathering at least 10 high-quality contributions, this Special Issue will provide a comprehensive overview of this interdisciplinary field and may be printed in book form.
For this Special Issue, original research articles, short communications, and reviews are welcome. Research areas may include (but are not limited to) the following:
- Mechanisms of cell division, cell cycle regulation, and systemic dysregulation;
- Genetic and epigenetic regulation in health and disease;
- Molecular biomarkers in cancer, infectious diseases, and neurodegeneration;
- Cellular senescence, oxidative stress, and inflammation in chronic diseases and diseases of civilization;
- Tumor microenvironment and cancer immunology;
- Neuroinflammation, blood–brain barrier biology, and neurodegenerative disorders;
- Multi-omics and single-cell approaches in biomarker discovery;
- Translational research and clinical applications of genetic and molecular insights.
We look forward to receiving your contributions and creating a comprehensive resource that will advance our understanding of how cellular and genetic mechanisms drive systemic diseases.
Dr. Robert Zdanowski
Guest Editor
Dr. Agata Borkowska
Guest Editor Assistant
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biology is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- cell cycle regulation
- genetic and epigenetic mechanisms
- cellular senescence
- oxidative stress
- inflammation
- molecular biomarkers
- neurodegeneration
- tumor microenvironment
- metabolic and cardiovascular diseases
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