Molecular, Biophysical, and Neurophysiological Mechanisms Underlying Magnetoreception

A special issue of Biology (ISSN 2079-7737).

Deadline for manuscript submissions: 30 October 2026 | Viewed by 977

Special Issue Editors


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Guest Editor
Beijing Key Laboratory of Bioelectromagnetics, Institute of Electrical Engineering, Chinese Academy of Sciences, Beijing 100190, China
Interests: bielectromagnetics; entomology; magnetosensing; migration; navigation
State Key Laboratory of Agricultural and Forestry Biosecurity, Department of Entomology, College of Plant Protection, Nanjing Agricultural University, Nanjing 210095, China
Interests: migratory insects; regulation of insect migration; insect orientation; insect magnetoreception; insect magnetobiology; insect circadian clock
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Special Issue Information

Dear Colleagues, 

Magnetoreception is the ability of animals to detect the Earth’s magnetic field for the purpose of orientation and navigation during long distance migration across species of many major phyla. For over 40 years, there has been an increasing interest in the understanding of molecular, biophysical, and neurophysiological mechanisms underlying magnetoreception. The following several models have been proposed to explain the nature of magnetoreception magnetite-based model, as shown in magnetotactic bacteria and Apis mellifera; radical-pair–reaction-based chemical model, as highlighted by radical pairs formed with the photoexcitation of cryptochrome in animals and plants; and the model of detecting minute electric fields by rs in elasmobranch animals.

The above-mentioned models have credible theoretical and experimental foundations, and may not be mutually exclusive; however, evidence from distinct species tends to surpass one theory over the other. Therefore, the existence of multiple molecular, biophysical, and neurophysiological mechanisms underlying magnetoreception is possible. The central questions lie in whether phylogenetically proximate animals utilize akin mechanisms to sense magnetic fields but decode them differently.

This Special Issue, titled “Molecular, Biophysical, and Neurophysiological Mechanisms Underlying Magnetoreception”, aims to gather and publish recent proceedings in the field of magnetoreception. We welcome all reviews and research articles regarding mechanisms involved in magnetoreception in animals at molecular, biophysical, and neurophysiological levels. This also includes experimental research and theoretical analysis. Topics of interest include the following:

  • Hypomagnetic or weak magnetic fields.
  • Behavioral phenomena in birds and other species, including humans.
  • Underlying mechanisms with magnetoreception.
  • Identification and characterization of specific magnetic receptors.
  • Hardware and software construction for magnetoreception research.
  • Computational simulation and experimental assessment.

We look forward to receiving your contributions. 

Prof. Dr. Weidong Pan
Dr. Guijun Wan
Guest Editors

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Keywords

  • earth magnetic field
  • magnetosensing
  • magnetite
  • radical pair
  • orientation
  • navigation
  • magnetic receptor
  • electroreceptor
  • neurophysiology

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Published Papers (1 paper)

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Research

16 pages, 2014 KB  
Article
Hypomagnetic Fields Influence the Developmental Duration, Fecundity and Temperature Stress Resistance of Drosophila melanogaster via Frataxin-Associated Traits
by Huiming Kang, Guijun Wan, Junzheng Zhang and Weidong Pan
Biology 2026, 15(5), 391; https://doi.org/10.3390/biology15050391 - 27 Feb 2026
Viewed by 612
Abstract
Frataxin is a highly conserved mitochondrial protein that plays a key role in iron homeostasis and metabolism, and its deficiency leads to oxidative stress, mitochondrial dysfunction, and neurodegeneration. Hypomagnetic fields (HMF) can lead to various biological effects including increased oxidative stress, neurological and [...] Read more.
Frataxin is a highly conserved mitochondrial protein that plays a key role in iron homeostasis and metabolism, and its deficiency leads to oxidative stress, mitochondrial dysfunction, and neurodegeneration. Hypomagnetic fields (HMF) can lead to various biological effects including increased oxidative stress, neurological and developmental disorders; yet, their effects acting as environmental stressors that exacerbate the inherent metabolic vulnerabilities in frataxin-deficient Drosophila melanogaster flies are still unknown. In this study, the bio-effects of HMF on growth, development, reproduction, and temperature stress resistance of frataxin-silenced flies were investigated. The results showed that HMF extended egg-to-adult and pupa developmental durations of both the control line of repo-GAL4; tub-GAL80^ts>GFP-RNAi (GFP-RNAi) and frataxin-deficient line of repo-GAL4; tub-GAL80^ts>fh RNAi (fh-RNAi) compared to those reared under a geomagnetic field (GMF). Compared with GMF, HMF significantly increased offspring fecundity in fh-RNAi flies, whereas the change in GFP-RNAi controls was not significant, while showing no significant effects on the adult weight of fh-RNAi flies. The impact of HMF on temperature stress resistance was particularly specific: it enhanced recovery from chill coma in control (GFP-RNAi) flies, while it accelerated recovery from heat shock in frataxin-silenced (fh-RNAi) flies. The mechanisms through which HMF modulate frataxin-associated phenotypes at a fundamental physical level warrant further investigation. Full article
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