Search for Articles:
Title / Keyword
Author / Affiliation / Email
Journal
Article Type
 
 
Advanced Search
 
Section
Special Issue
Volume
Issue
Number
Page
 
7.3
4.3
Journals
Antibiotics
Special Issues
Antimicrobial Stewardship and Infection Prevention in Intensive Care Unit
share announcement

Antimicrobial Stewardship and Infection Prevention in Intensive Care Unit

A special issue of Antibiotics (ISSN 2079-6382). This special issue belongs to the section "Antibiotic Therapy in Infectious Diseases".

Deadline for manuscript submissions: 20 June 2025 | Viewed by 1812

Special Issue Editors

Dr. Mihai Sava

E-Mail Website
Guest Editor
1. Faculty of Medicine, Lucian Blaga University of Sibiu, Lucian Blaga Street 2A, 550169 Sibiu, Romania
2. County Clinical Emergency Hospital, Bld. Corneliu Coposu, nr. 2-4, 550245 Sibiu, Romania
Interests: medical management; antimicrobial stewardship; blood purification techniques
Prof. Dr. Majdi N. Al-Hasan

E-Mail Website
Guest Editor
School of Medicine, University of South Carolina, Columbia, SC 29208, USA
Interests: antimicrobial stewardship; antimicrobial resistance; bloodstream infections; sepsis; Gram-negative bacteria; antibiotics; antibacterial agents; urinary tract infections
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

As healthcare professionals, we are constantly aware of the pressing challenges posed by infections in the ICU, particularly as we face the growing threat of antimicrobial resistance.

This Special Issue aims to explore innovative strategies and best practices that have enhanced our efforts in both antimicrobial stewardship and infection prevention. We invite you to share your valuable research, case studies, and reviews that contribute to this critical subject. Your expertise can make a significant difference, helping to shape our understanding and guide our efforts to improve patient outcomes and safety in the ICU.

Submissions on various topics are welcomed, including but not limited to novel prevention strategies, the implementation of stewardship programs, and insights on managing healthcare-associated infections. We believe your input will be valuable in fostering deeper understanding and collaboration within our medical community.

We are truly grateful for your potential contribution. Please consider submitting your manuscript by deadline and join us in advancing the discourse on these prime-time topics.

Dr. Mihai Sava
Prof. Dr. Majdi N. Al-Hasan
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Antibiotics is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • antimicrobial stewardship
  • infection prevention
  • intensive care unit (ICU)
  • antimicrobial resistance
  • healthcare-associated infections
  • patient safety

Benefits of Publishing in a Special Issue

  • Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
  • Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
  • Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
  • External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
  • Reprint: MDPI Books provides the opportunity to republish successful Special Issues in book format, both online and in print.

Further information on MDPI's Special Issue policies can be found here.

Published Papers (1 paper)

Order results
Result details
Show export options expand_more Show export options expand_less
Select all
Export citation of selected articles as:

Research

10 pages, 914 KiB  
Article
Impact of Haemoadsorption Therapy on Short Term Mortality and Vasopressor Dependency in Severe Septic Shock with Acute Kidney Injury: A Retrospective Cohort Study
by Danny Epstein, Karawan Badarni and Yaron Bar-Lavie
Antibiotics 2024, 13(12), 1233; https://doi.org/10.3390/antibiotics13121233 - 22 Dec 2024
Viewed by 1345
Abstract
Background/Objectives: Sepsis, a life-threatening organ dysfunction caused by a dysregulated host response to infection, remains a major challenge in ICUs. This study evaluated whether combining haemoadsorption therapy with continuous renal replacement therapy (CRRT) reduces ICU and short-term mortality in patients with severe [...] Read more.
Background/Objectives: Sepsis, a life-threatening organ dysfunction caused by a dysregulated host response to infection, remains a major challenge in ICUs. This study evaluated whether combining haemoadsorption therapy with continuous renal replacement therapy (CRRT) reduces ICU and short-term mortality in patients with severe septic shock and acute kidney injury (AKI) requiring CRRT. Methods: A single-centre retrospective cohort study was conducted at Rambam Health Care Campus, Haifa, Israel, from January 2018 to February 2024. Data were collected from ICU patients with severe septic shock and AKI requiring CRRT. Patients were divided into two groups: those receiving haemoadsorption therapy with CRRT and those receiving CRRT alone. Primary and secondary endpoints included ICU, 30 and 60-day mortality, vasopressor dependency index (VDI), and lactate levels. Results: Out of 545 patients with septic shock, 133 developed AKI requiring CRRT, and 76 met the inclusion criteria. The haemoadsorption group (n = 47) showed significant reductions in blood lactate levels and VDI after 24 h compared to the CRRT alone group (n = 29). ICU mortality was significantly lower in the haemoadsorption group (34.0% vs. 65.5%, p = 0.008), as was 30 and 60-day mortality (34.0% vs. 62.1%, p = 0.02, and 48.9% vs. 75.9%, p = 0.002). Multivariate analysis confirmed haemoadsorption therapy as independently associated with lower ICU and 30-day but not 60-day mortality. Conclusions: Haemoadsorption therapy combined with CRRT in patients with severe septic shock and AKI requiring CRRT is associated with improved lactate clearance, reduced vasopressor requirements, and lower ICU and 30-day mortality. Further high-quality randomized controlled trials are needed to confirm these findings. Full article
(This article belongs to the Special Issue Antimicrobial Stewardship and Infection Prevention in Intensive Care Unit)
►▼ Show Figures

Figure 1

Show export options expand_more Show export options expand_less
Select all
Export citation of selected articles as:
 
Displaying articles 1-1
Back to TopTop