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Tropical Medicine and Infectious Disease, Volume 7, Issue 12

2022 December - 56 articles

Cover Story: Cancer and parasitic diseases share similarities that allow for the co-development of new drugs with antiproliferative profiles. We describe herein the design of a series of 1,2,4-oxadiazoles active against both cancer cells and trypanosomatid parasites. One hit compound was identified during in vitro evaluation against drug-sensitive and drug-resistant chronic myeloid leukemia cell lines, Trypanosoma cruzi and Leishmania amazonensis. In silico studies indicate a correlation between in vitro activity and interaction with tubulin at the colchicine binding site. Additionally, ADMET in silico predictions and experimental studies with human serum albumin indicate that the compounds possess a favorable druggability potential due to their physicochemical, pharmacokinetic, and toxicity profiles. View this paper
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Articles (56)

  • Article
  • Open Access
9 Citations
4,684 Views
12 Pages

Distribution of Mycobacterium tuberculosis Lineages and Drug Resistance in Upper Myanmar

  • Aye Nyein Phyu,
  • Si Thu Aung,
  • Prasit Palittapongarnpim,
  • Kyaw Ko Ko Htet,
  • Surakameth Mahasirimongkol,
  • Htin Lin Aung,
  • Angkana Chaiprasert and
  • Virasakdi Chongsuvivatwong

Mycobacterium tuberculosis complex (MTBC) is divided into 9 whole genome sequencing (WGS) lineages. Among them, lineages 1–4 are widely distributed. Multi-drug resistant tuberculosis (MDR-TB) is a major public health threat. For effective TB co...

  • Article
  • Open Access
3 Citations
2,509 Views
14 Pages

COVID-19 Risk Perception and Prevention Practices among High- and Low-Density Populations in Bangladesh: A Mixed-Methods Study

  • Syed Moinuddin Satter,
  • Kamal Ibne Amin Chowdhury,
  • Refah Tamanna,
  • Zarin Abdullah,
  • S. M. Zafor Shafique,
  • Md Saiful Islam,
  • Nadia Ali Rimi,
  • Muhammad Rashedul Alam,
  • Arifa Nazneen and
  • Sayera Banu
  • + 9 authors

We aimed to explore coronavirus disease 2019 (COVID-19) risk perception and prevention practices among people living in high- and low-population density areas in Dhaka, Bangladesh. A total of 623 patients with confirmed COVID-19 agreed to participate...

  • Article
  • Open Access
8 Citations
3,355 Views
14 Pages

Evaluation of Methods for Collecting Mosquitoes (Culicidae: Diptera) in Canopy and Ground Strata in the Brazilian Savanna

  • Luis Filipe Mucci,
  • Eduardo Sterllino Bergo,
  • Juliana Telles de Deus,
  • Simone Luchetta Reginato,
  • Mariza Pereira and
  • Vera Lucia Fonseca de Camargo-Neves

The hand-net is the standard method for capturing mosquitoes with sylvatic diurnal activity in disease outbreaks in Brazil. However, occupational risks and biases related to the collectors’ abilities and attractiveness are important limitations...

  • Article
  • Open Access
16 Citations
3,596 Views
13 Pages

Trypanosoma cruzi Parasite Burdens of Several Triatomine Species in Colombia

  • Natalia Velásquez-Ortiz,
  • Carolina Hernández,
  • Omar Cantillo-Barraza,
  • Nathalia Ballesteros,
  • Lissa Cruz-Saavedra,
  • Giovanny Herrera,
  • Luz Stella Buitrago,
  • Hugo Soto,
  • Manuel Medina and
  • Juan David Ramírez
  • + 7 authors

Trypanosoma cruzi, the causal agent of Chagas disease, is mainly transmitted by insects of the Triatominae subfamily. In Colombia, there are 26 triatomine species, and 16 of them are naturally infected with the parasite. The parasite loads of natural...

  • Review
  • Open Access
15 Citations
4,790 Views
10 Pages

Cutaneous Leishmaniasis Emergence in Southeastern Mexico: The Case of the State of Yucatan

  • Elsy B. Canché-Pool,
  • Jesús A. Panti-May,
  • Hugo A. Ruiz-Piña,
  • Marco Torres-Castro,
  • Francisco J. Escobedo-Ortegón,
  • Paulino Tamay-Segovia,
  • Selene Blum-Domínguez,
  • Jimmy R. Torres-Castro and
  • Enrique Reyes-Novelo

Environmental changes triggered by deforestation, urban expansion and climate change are present-day drivers of the emergence and reemergence of leishmaniasis. This review describes the current epidemiological scenario and the feasible influence of e...

  • Case Report
  • Open Access
5 Citations
2,215 Views
6 Pages

First Human Usutu Virus Reported in Asti (Piedmont, Italy, August 2022) and Early Follow-Up

  • Tommaso Lupia,
  • Fabio Paolo Marletto,
  • Ilvana Tiziana Scuvera,
  • Roberta Bosio,
  • Barbara Rizzello,
  • Valentina Fornari,
  • Daniela Maria Luisa Vivenza,
  • Valeria Ghisetti,
  • Maria Teresa Brusa and
  • Francesco Giuseppe De Rosa
  • + 1 author

The Usutu virus (USUV) has recently attracted the attention of scientists because of its rapid spread across Europe and its growth over the previous seasons in Italy. Here, we describe the first case of USUV infection in Asti, Piedmont region, Italy....

  • Article
  • Open Access
4 Citations
3,899 Views
15 Pages

Different In Vitro Drug Susceptibility Profile of Plasmodium falciparum Isolates from Two Adjacent Areas of Northeast Myanmar and Molecular Markers for Drug Resistance

  • Mengxi Duan,
  • Yao Bai,
  • Shuang Deng,
  • Yonghua Ruan,
  • Weilin Zeng,
  • Xiaosong Li,
  • Xun Wang,
  • Wei Zhao,
  • Hui Zhao and
  • Liwang Cui
  • + 6 authors

The Greater Mekong Subregion (GMS) is the epicenter of antimalarial drug resistance. We determined in vitro susceptibilities to 11 drugs of culture-adapted Plasmodium falciparum isolates from adjacent areas (Laiza and Muse) along the China–Myan...

  • Article
  • Open Access
2 Citations
4,212 Views
8 Pages

Individuals’ Vulnerability Based Active Surveillance for TB: Experiences from India

  • Shibu K. Balakrishnan,
  • Rakesh P. Suseela,
  • Sunilkumar Mrithyunjayan,
  • Manu E. Mathew,
  • Suresh Varghese,
  • Shubin Chenayil,
  • Suja Aloysius,
  • Twinkle Prabhakaran and
  • Sreenivas A. Nair

Community-based active TB case finding (ACF) has become an essential part of TB elimination efforts in high-burden settings. In settings such as the state of Kerala in India, which has reported an annual decline of 7.5% in the estimated TB incidence...

  • Article
  • Open Access
5 Citations
2,489 Views
8 Pages

Diagnostic Performance of Plasmodium falciparum Histidine-Rich Protein-2 Antigen-Specific Rapid Diagnostic Test in Children at the Peripheral Health Care Level in Nanoro (Burkina Faso)

  • Massa dit Achille Bonko,
  • Marc Christian Tahita,
  • Francois Kiemde,
  • Palpouguini Lompo,
  • Petra F. Mens,
  • Halidou Tinto and
  • Henk. D. F. H. Schallig

(1) Background: Malaria control has strongly benefited from the implementation of rapid diagnostic tests (RDTs). The malaria RDTs used in Burkina Faso, as per the recommendation of the National Malaria Control Program, are based on the detection of h...

  • Review
  • Open Access
16 Citations
5,930 Views
15 Pages

Human cytomegalovirus (HCMV) is ubiquitous worldwide and elicits global health problems. The diseases associated with HCMV are a serious threat to humans, especially for the sick, infant, elderly and immunocompromised/immunodeficient individuals. Alt...

  • Review
  • Open Access
19 Citations
8,758 Views
26 Pages

Diversity and Dissemination of Methicillin-Resistant Staphylococcus aureus (MRSA) Genotypes in Southeast Asia

  • Nurul Amirah Mohamad Farook,
  • Silvia Argimón,
  • Muttaqillah Najihan Abdul Samat,
  • Sharifah Azura Salleh,
  • Sunita Sulaiman,
  • Toh Leong Tan,
  • Petrick Periyasamy,
  • Chee Lan Lau,
  • Zalina Ismail and
  • Hui-min Neoh
  • + 2 authors

Methicillin-resistant Staphylococcus aureus (MRSA) is a successful pathogen that has achieved global dissemination, with high prevalence rates in Southeast Asia. A huge diversity of clones has been reported in this region, with MRSA ST239 being the m...

  • Article
  • Open Access
7 Citations
2,872 Views
17 Pages

Evaluation of Amino Acids Profile as Non-Invasive Biomarkers of Hepatocellular Carcinoma in Egyptians

  • Samar Ebrahim Ghanem,
  • Mohamed Abdel-Samiee,
  • Hala El-Said,
  • Mohamed I. Youssef,
  • Hassan Ahmed ElZohry,
  • Eman Abdelsameea,
  • Inas Moaz,
  • Sayed F. Abdelwahab,
  • Shymaa A. Elaskary and
  • Marwa Lotfy Helal
  • + 1 author

Background: Hepatocellular carcinoma (HCC) is the most dangerous complication of chronic liver disease. It is a multifactorial complicated disease. Hepatitis C and hepatitis B viruses (HCV and HBV, respectively) represent the main causes of HCC in Eg...

  • Article
  • Open Access
3 Citations
2,209 Views
12 Pages

Introduction: This study explored the understanding of healthcare professionals on the role of the District Clinical Specialist Team (DCST) and how the team works together with the district personnel at different management levels to improve and stre...

  • Article
  • Open Access
1 Citations
1,899 Views
11 Pages

Airports could serve as hotspots for the spread of the COVID-19 infection. We aimed to assess the awareness, attitude, and behaviors of non-Saudi travelers about COVID-19 and their satisfaction with preventive measures at Saudi airports. A cross-sect...

  • Case Report
  • Open Access
6 Citations
3,394 Views
7 Pages

Fatal Case of Imported Tick-Borne Encephalitis in South Serbia

  • Lidija Popović Dragonjić,
  • Miodrag Vrbić,
  • Aleksandar Tasić,
  • Verica Simin,
  • Ivana Bogdan,
  • Dragana Mijatović,
  • Alejandro Cabezas-Cruz and
  • Pavle Banović

Tick-borne encephalitis (TBE) is vaccine-preventable neglected zoonotic neuroinvasive disease, caused by tick-borne encephalitis virus (TBEV). Many of the Central and Eastern European countries are affected by TBE, which is often poorly perceived by...

  • Review
  • Open Access
17 Citations
3,996 Views
24 Pages

Climatic and Environmental Factors Influencing COVID-19 Transmission—An African Perspective

  • Allan Mayaba Mwiinde,
  • Enock Siankwilimba,
  • Masauso Sakala,
  • Faustin Banda and
  • Charles Michelo

Since the outbreak of COVID-19 was decreed by the World Health Organization as a public health emergency of worldwide concern, the epidemic has drawn attention from all around the world. The disease has since spread globally in developed and developi...

  • Article
  • Open Access
2,552 Views
12 Pages

Clinical-Epidemiological Characteristics and Outcomes of Latent Tuberculosis Treatment at a Tertiary Center in Central-West Brazil from 2017 to 2019

  • Moara Alves Santa Bárbara Borges,
  • Iago Dib Cunha,
  • Luís Henrique Candini,
  • Vitor Alves de Souza and
  • Paulo Sérgio Sucasas da Costa

Detailed information concerning latent tuberculosis infection (LTBI) and treatment outcomes is scarce in Brazil. This retrospective cross-sectional study aimed to describe LTB treatment (LTBT) at a tertiary center in Central-West Brazil from 2017 to...

  • Article
  • Open Access
6 Citations
2,929 Views
16 Pages

Predicting the Impact of Climate Change on the Distribution of a Neglected Arboviruses Vector (Armigeres subalbatus) in China

  • Gang Wang,
  • Dongjing Zhang,
  • Jehangir Khan,
  • Jiatian Guo,
  • Qingdeng Feng,
  • Yan Sun,
  • Beiqing Li,
  • Yu Wu,
  • Zhongdao Wu and
  • Xiaoying Zheng

The geographic boundaries of arboviruses continue to expand, posing a major health threat to millions of people around the world. This expansion is related to the availability of effective vectors and suitable habitats. Armigeres subalbatus (Coq...

  • Article
  • Open Access
4 Citations
5,584 Views
15 Pages

Toxoplasmosis is a zoonotic parasitic disease caused by T. gondii, an obligate intracellular apcomplexan zoonotic parasite that is geographically worldwide in distribution. The parasite infects humans and all warm-blooded animals and is highly preval...

  • Case Report
  • Open Access
7 Citations
3,621 Views
5 Pages

COVID-19 and Pasteurella multocida Pulmonary Coinfection: A Case Series

  • Ornella Cabras,
  • Jean-Marie Turmel,
  • Claude Olive,
  • Bastien Bigeard,
  • Mélanie Lehoux,
  • Sandrine Pierre-Francois,
  • Karine Guitteaud,
  • Sylvie Abel,
  • Lise Cuzin and
  • André Cabié

Objectives: In COVID-19 patients, bacterial and fungal pulmonary coinfections, such as Streptococcus pneumoniae, Staphylococcus aureus, Haemophilus influenzae, or Aspergillus, have been reported, but to our knowledge, no case has been reported due to...

  • Article
  • Open Access
14 Citations
4,282 Views
14 Pages

Is Borrelia burgdorferi Sensu Stricto in South America? First Molecular Evidence of Its Presence in Colombia

  • Lorys Y. Mancilla-Agrono,
  • Lizeth F. Banguero-Micolta,
  • Paula A. Ossa-López,
  • Héctor E. Ramírez-Chaves,
  • Gabriel J. Castaño-Villa and
  • Fredy A. Rivera-Páez

The genus Borrelia encompasses spirochetal species that are part of three well-defined groups. Two of these groups contain pathogens that affect humans: the group causing Lyme disease (LDG) and the relapsing fever group (RFG). Lyme disease is caused...

  • Article
  • Open Access
2 Citations
3,790 Views
14 Pages

Leptospiral Leucine-Rich Repeat Protein-Based Lateral Flow for Assessment of Canine Leptospiral Immunoglobulin G

  • Sineenat Sripattanakul,
  • Kanpapat Boonchuay,
  • Teerasak Prapong,
  • Worawidh Wajjwalku,
  • Gerd Katzenmeier,
  • Dietmar Haltrich,
  • Ratchanee Hongprayoon and
  • Siriwan Prapong

The recombinant, modified leucine-rich repeat protein rhKU_Sej_LRR_2271 has been suggested as a candidate for leptospiral vaccine development since it was predicted to be a transmembrane protein containing leucine-rich repeat motifs and immunogenic e...

  • Article
  • Open Access
20 Citations
6,061 Views
16 Pages

Environmental Factors Affecting Freshwater Snail Intermediate Hosts in Shenzhen and Adjacent Region, South China

  • Fengyang Min,
  • Jiasheng Wang,
  • Xiaoguang Liu,
  • Yi Yuan,
  • Yunhai Guo,
  • Kongxian Zhu,
  • Zhaohui Chai,
  • Yunchao Zhang and
  • Shizhu Li

Sound knowledge of the local distribution and diversity of freshwater snail intermediate hosts and the factors driving the occurrence and abundance of them is crucial to understanding snail-borne parasitic disease transmission and to setting up effec...

  • Article
  • Open Access
11 Citations
3,033 Views
25 Pages

The COVID-19 Infodemic on Twitter: A Space and Time Topic Analysis of the Brazilian Immunization Program and Public Trust

  • Victor Diogho Heuer de Carvalho,
  • Thyago Celso Cavalcante Nepomuceno,
  • Thiago Poleto and
  • Ana Paula Cabral Seixas Costa

The context of the COVID-19 pandemic has brought to light the infodemic phenomenon and the problem of misinformation. Agencies involved in managing COVID-19 immunization programs are also looking for ways to combat this problem, demanding analytical...

  • Article
  • Open Access
42 Citations
3,724 Views
24 Pages

While the world is still struggling to recover from the harm caused by the widespread COVID-19 pandemic, the monkeypox virus now poses a new threat of becoming a pandemic. Although it is not as dangerous or infectious as COVID-19, new cases of the di...

  • Article
  • Open Access
14 Citations
22,330 Views
17 Pages

Background: To confirm the suspicion of scabies, dermatologists have one pathognomonic sign, “the tunnel” through which Sarcoptes scabiei digs into the epidermis. Light microscopy is considered the most reliable procedure, but it is time-...

  • Systematic Review
  • Open Access
9 Citations
3,980 Views
19 Pages

Malaria in pregnancy (MiP) is a global public health problem; its research is predominantly quantitative. The objective was to analyze the individual, cultural and socioeconomic determinants of the treatment and prevention of MiP with a systematic re...

  • Article
  • Open Access
4 Citations
2,882 Views
12 Pages

COVID-19 Alcoholic Cirrhosis and Non-Alcoholic Steatohepatitis Cirrhosis Outcomes among Hospitalized Patients in the United States: Insight from National Inpatient Sample Database

  • Devika Kapuria,
  • Karthik Gangu,
  • Prabal Chourasia,
  • Aniesh Boba,
  • Anthony Nguyen,
  • Moon Ryu,
  • Mark Peicher,
  • Mario Flores,
  • Harleen Kaur Chela and
  • Rahul Shekhar
  • + 2 authors

Patients with co-morbidities like cirrhosis are at risk of worse outcome from COVID-19 infection. Given limited prior studies, we evaluated outcomes associated with COVID-19 infection in alcoholic and non-alcoholic steatohepatitis cirrhotic (CC+) ver...

  • Article
  • Open Access
16 Citations
4,254 Views
12 Pages

Analysis of a Dengue Virus Outbreak in Rosso, Senegal 2021

  • Idrissa Dieng,
  • Mamadou Aliou Barry,
  • Cheikh Talla,
  • Bocar Sow,
  • Oumar Faye,
  • Moussa Moise Diagne,
  • Ousseynou Sene,
  • Oumar Ndiaye,
  • Boly Diop and
  • Ousmane Faye
  • + 4 authors

Senegal is hyperendemic for dengue. Since 2017, outbreaks have been noticed annually in many regions around the country, marked by the co-circulation of DENV1-3. On 8 October 2021, a Dengue virus outbreak in the Rosso health post (sentinel site of th...

  • Article
  • Open Access
14 Citations
2,305 Views
14 Pages

Main Predictors of COVID-19 Vaccination Uptake among Italian Healthcare Workers in Relation to Variable Degrees of Hesitancy: Result from a Cross-Sectional Online Survey

  • Marco Trabucco Aurilio,
  • Francesco Saverio Mennini,
  • Cristiana Ferrari,
  • Giuseppina Somma,
  • Luca Di Giampaolo,
  • Matteo Bolcato,
  • Fabio De-Giorgio,
  • Roberto Muscatello,
  • Andrea Magrini and
  • Luca Coppeta

Background: Hesitancy remains one of the major hurdles to vaccination, regardless of the fact that vaccines are indisputable preventive measures against many infectious diseases. Nevertheless, vaccine hesitancy or refusal is a growing phenomenon in t...

  • Article
  • Open Access
7 Citations
4,090 Views
9 Pages

Drug-Resistant Tuberculosis Treatment Outcomes among Children and Adolescents in Karachi, Pakistan

  • Amyn A. Malik,
  • Uzma Khan,
  • Palwasha Khan,
  • Aliya Anwar,
  • Naseem Salahuddin,
  • Saira Khowaja,
  • Aamir J. Khan,
  • Salman Khan,
  • Hamidah Hussain and
  • Farhana Amanullah

Background: Significant data gaps exist for children and adolescents with drug-resistant (DR) TB, particularly from high TB incidence settings. This report provides a descriptive analysis of programmatic outcomes among children and adolescents treate...

  • Article
  • Open Access
8 Citations
4,082 Views
26 Pages

Antiplasmodial Properties of Aqueous and Ethanolic Extracts of Ten Herbal Traditional Recipes Used in Thailand against Plasmodium falciparum

  • Arisara Phuwajaroanpong,
  • Prapaporn Chaniad,
  • Walaiporn Plirat,
  • Sathianpong Phoopha,
  • Abdi Wira Septama,
  • Arnon Chukaew and
  • Chuchard Punsawad

This study evaluated the in vitro and in vivo antiplasmodial efficacy and toxicity of aqueous and ethanolic extracts from traditional recipes used in Thailand. The aqueous and ethanolic extracts of ten traditional recipes were tested for in vitro ant...

  • Article
  • Open Access
3 Citations
2,926 Views
12 Pages

Evaluation of Chiral Organosulfur Compounds on Their Activity against the Malaria Parasite Plasmodium falciparum

  • Che Julius Ngwa,
  • Rabea Stratmann,
  • Jean Pierre Musabyimana,
  • Kristina Pannen,
  • Jan-Hendrik Schöbel,
  • Marcus Frings,
  • Ingo Schiffers,
  • Calogero Quaranta,
  • Steffen Koschmieder and
  • Carsten Bolm
  • + 2 authors

Malaria is one of the deadliest tropical diseases, especially causing havoc in children under the age of five in Africa. Although the disease is treatable, the rapid development of drug resistant parasites against frontline drugs requires the search...

  • Article
  • Open Access
17 Citations
4,380 Views
12 Pages

Treatments and Predictors of Mortality for Carbapenem-Resistant Gram-Negative Bacilli Infections in Malaysia: A Retrospective Cohort Study

  • Usman Abubakar,
  • Amni Izzati Zulkarnain,
  • Jesús Rodríguez-Baño,
  • Norhidayah Kamarudin,
  • Mahmoud E. Elrggal,
  • Mohamed Hassan Elnaem and
  • Sabariah Noor Harun

This study evaluated the treatments, mortality rate and patient-related factors associated with mortality. This is a retrospective study involving hospitalised patients with infections caused by carbapenem-resistant Gram-negative bacilli (CR-GNB) in...

  • Systematic Review
  • Open Access
23 Citations
4,873 Views
19 Pages

Prevalence of Mutated Colistin-Resistant Klebsiella pneumoniae: A Systematic Review and Meta-Analysis

  • Nik Yusnoraini Yusof,
  • Nur Iffah Izzati Norazzman,
  • Siti Nur’ain Warddah Ab Hakim,
  • Mawaddah Mohd Azlan,
  • Amy Amilda Anthony,
  • Fatin Hamimi Mustafa,
  • Naveed Ahmed,
  • Ali A. Rabaan,
  • Souad A. Almuthree and
  • Chan Yean Yean
  • + 5 authors

The emergence of genetic mutations in chromosomal genes and the transmissible plasmid-mediated colistin resistance gene may have helped in the spread of colistin resistance among various Klebsiella pneumoniae (K. pneumoniae) isolates and other differ...

  • Article
  • Open Access
16 Citations
3,293 Views
24 Pages

Identification of Bacterial Communities and Tick-Borne Pathogens in Haemaphysalis spp. Collected from Shanghai, China

  • Wenbo Zeng,
  • Zhongqiu Li,
  • Tiange Jiang,
  • Donghui Cheng,
  • Limin Yang,
  • Tian Hang,
  • Lei Duan,
  • Dan Zhu,
  • Yuan Fang and
  • Yi Zhang

Ticks can carry and transmit a large number of pathogens, including bacteria, viruses and protozoa, posing a huge threat to human health and animal husbandry. Previous investigations have shown that the dominant species of ticks in Shanghai are Haema...

  • Article
  • Open Access
8 Citations
3,996 Views
17 Pages

Genetic Diversity, Haplotype Relationships, and kdr Mutation of Malaria Anopheles Vectors in the Most Plasmodium knowlesi-Endemic Area of Thailand

  • Tanawat Chaiphongpachara,
  • Sedthapong Laojun,
  • Tanasak Changbunjong,
  • Suchada Sumruayphol,
  • Nantana Suwandittakul,
  • Sakultip Chookaew and
  • Yuppayong Atta

Plasmodium knowlesi, a malaria parasite that occurs naturally in long-tailed macaques, pig-tailed macaques, and banded leaf monkeys, is currently regarded as the fifth of the human malaria parasites. We aimed to investigate genetic diversity based on...

  • Article
  • Open Access
24 Citations
5,059 Views
18 Pages

Conspiratorial Attitude of the General Public in Jordan towards Emerging Virus Infections: A Cross-Sectional Study Amid the 2022 Monkeypox Outbreak

  • Malik Sallam,
  • Huda Eid,
  • Nour Awamleh,
  • Ala’a B. Al-Tammemi,
  • Muna Barakat,
  • Rabaa Y. Athamneh,
  • Souheil Hallit,
  • Harapan Harapan and
  • Azmi Mahafzah

Conspiracy theories accompany the emergence of infectious diseases and the 2022 multi-country monkeypox (MPX) outbreak is no exception. It is possible that the adoption of conspiracy beliefs negatively impacts health behavior. We aimed to assess the...

  • Article
  • Open Access
7 Citations
2,982 Views
13 Pages

Mosquito Fauna and Spatial Distribution in an Atlantic Forest Area in Rio de Janeiro State, Brazil, Reveal a High Risk of Transmission of Yellow Fever and Other Arboviruses

  • Rafaella Moraes de Miranda,
  • Anielly Ferreira-de-Brito,
  • Júlia dos Santos Silva,
  • Alexandre da Silva Xavier,
  • Shayenne Olsson Freitas Silva,
  • Jeronimo Alencar and
  • Ricardo Lourenço-de-Oliveira

In 2017–2019, Brazil recorded its most severe outbreak of yellow fever due to the spread of the virus (YFV) in the country’s southeast. Here, we investigated mosquito fauna and the spatial distribution of species in a primatology center in the Atlant...

  • Article
  • Open Access
1 Citations
2,088 Views
12 Pages

Health-Related Quality of Life, Pain and Sleep in Patients with HIV Depending on the Clinical Situation: A Cross-Sectional Pilot Study

  • Jon Salmanton-García,
  • Francisco Alburquerque-Sendín,
  • Javier Martín-Vallejo,
  • Alicia Iglesias-Gómez and
  • Miguel Cordero-Sánchez

Introduction: Health-related quality of life (HRQL), pain and sleep have been described as relevant traits in patients with human immunodeficiency virus (HIV). The aim of this study is to describe and evaluate HRQL, pain and sleep and their interdepe...

  • Article
  • Open Access
3 Citations
2,952 Views
11 Pages

Dengue Meteorological Determinants during Epidemic and Non-Epidemic Periods in Taiwan

  • Shu-Han You,
  • Szu-Chieh Chen,
  • Yi-Han Huang and
  • Hsin-Chieh Tsai

The identification of the key factors influencing dengue occurrence is critical for a successful response to the outbreak. It was interesting to consider possible differences in meteorological factors affecting dengue incidence during epidemic and no...

  • Article
  • Open Access
8 Citations
2,920 Views
20 Pages

The Impact of COVID-19 Quarantine on Tuberculosis and Diabetes Mellitus Cases: A Modelling Study

  • Nuning Nuraini,
  • Ilham Saiful Fauzi,
  • Bony Wiem Lestari and
  • Sila Rizqina

COVID-19 has currently become a global pandemic and caused a high number of infected people and deaths. To restrain the coronavirus spread, many countries have implemented restrictions on people’s movement and outdoor activities. The enforcemen...

  • Case Report
  • Open Access
6 Citations
3,229 Views
11 Pages

Disseminated Human Subarachnoid Coenurosis

  • Jason Labuschagne,
  • John Frean,
  • Kaajal Parbhoo,
  • Denis Mutyaba,
  • Tanyia Pillay,
  • Shareen Boughan and
  • Hlezikuhle Nkala

Background: Traditionally, human coenurosis has been ascribed to Taenia multiceps while neurocysticercosis has been attributed solely to Taenia solium infection. Historically, however, the identification and differentiation of cestodal infection was...

  • Article
  • Open Access
12 Citations
4,119 Views
13 Pages

Mapping the Spatiotemporal Distribution of Bovine Rabies in Colombia, 2005–2019

  • D. Katterine Bonilla-Aldana,
  • S. Daniela Jimenez-Diaz,
  • Joshuan J. Barboza and
  • Alfonso J. Rodriguez-Morales

Introduction: Rabies is caused by a virus belonging to the genus Lyssavirus and family Rhabdoviridae, which can infect any mammal including humans. Hematophagous, fructivorous, and insectivorous bats have become the main reservoir of sylvatic rabies...

  • Article
  • Open Access
9 Citations
3,196 Views
24 Pages

West Nile Virus Infection: A Cross-Sectional Study on Italian Medical Professionals during Summer Season 2022

  • Matteo Riccò,
  • Alessandro Zaniboni,
  • Elia Satta,
  • Silvia Ranzieri,
  • Milena Pia Cerviere,
  • Federico Marchesi and
  • Simona Peruzzi

West Nile virus (WNV) has progressively endemized in large areas of continental Europe, and particularly in Northern Italy, in the Po River Valley. During summer season 2022, Italy experienced an unprecedented surge in incidence cases of WNV infectio...

  • Article
  • Open Access
5 Citations
4,803 Views
28 Pages

A Novel Protocol for the Synthesis of 1,2,4-Oxadiazoles Active against Trypanosomatids and Drug-Resistant Leukemia Cell Lines

  • Paulo Pitasse-Santos,
  • Eduardo Salustiano,
  • Raynná Bittencourt Pena,
  • Otávio Augusto Chaves,
  • Leonardo Marques da Fonseca,
  • Kelli Monteiro da Costa,
  • Carlos Antônio do Nascimento Santos,
  • Jhenifer Santos Dos Reis,
  • Marcos André Rodrigues da Costa Santos and
  • Marco Edilson Freire-de-Lima
  • + 7 authors

Cancer and parasitic diseases, such as leishmaniasis and Chagas disease, share similarities that allow the co-development of new antiproliferative agents as a strategy to quickly track the discovery of new drugs. This strategy is especially interesti...

  • Review
  • Open Access
8 Citations
3,395 Views
15 Pages

Global Research Trends on Monkeypox Virus: A Bibliometric and Visualized Study

  • Hafiz Muhammad Zeeshan,
  • Aqsa Rubab,
  • Hilda Dhlakama,
  • Ropo Ebenezer Ogunsakin and
  • Moses Okpeku

Monkeypox is a zoonotic viral disease that has recently emerged as another global infection disease. A double-stranded enveloped deoxyribonucleic acid virus the cause of this disease. Since monkeypox is an evolving field of study with a growing inter...

  • Article
  • Open Access
7 Citations
3,406 Views
26 Pages

Melatonin (MLT) is now emerging as one of the universally accepted immunostimulators with broad applications in medicine. It is a biological manipulator of the immune system, including mucosal ones. MLT was encapsulated in solid lipid nanoparticles (...

  • Article
  • Open Access
8 Citations
3,663 Views
11 Pages

Cutaneous leishmaniasis (CL), a vector-borne parasitic disease caused by the Leishmania protozoan, is a serious public health problem in Morocco. The treatment of this disease is still based on pentavalent antimonials as the primary therapy, but thes...

  • Article
  • Open Access
2 Citations
2,041 Views
22 Pages

The rapid suppression of SARS-CoV-2 transmission remains a priority for maintaining public health security throughout the world, and the agile adjustment of government prevention and control strategies according to the spread of the epidemic is cruci...

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Trop. Med. Infect. Dis. - ISSN 2414-6366