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Antibiotics, Volume 14, Issue 12

December 2025 - 113 articles

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Articles (113)

  • Review
  • Open Access
481 Views
13 Pages

18 December 2025

Background: Antimicrobial resistance (AMR) is accelerating globally, driven by widespread inappropriate antibiotic use and diagnostic uncertainty in primary care. Pharmcist-led point-of-care testing (POCTs) has emerged as a promising model to optimiz...

  • Systematic Review
  • Open Access
413 Views
29 Pages

Surveillance of Healthcare-Associated Infections in the WHO African Region: Systematic Review of Literature from 2011 to 2024

  • Laetitia Gahimbare,
  • Nathalie K. Guessennd,
  • Claude Mambo Muvunyi,
  • Walter Fuller,
  • Sheick Oumar Coulibaly,
  • Landry Cihambanya,
  • Pierre Claver Kariyo,
  • Olga Perovic,
  • Ambele Judith Mwamelo and
  • Diané Kouao Maxime
  • + 4 authors

18 December 2025

Background: Evidence on HAIs in Africa is fairly common. Objectives: The main objective was to identify the surveillance tools used for healthcare–associated infections (HAIs) in countries in the WHO African Region. Secondary objectives focused...

  • Review
  • Open Access
512 Views
19 Pages

Extended-Spectrum β-Lactamase-Producing Escherichia coli and Pediatric UTIs: A Review of the Literature and Selected Experimental Observations

  • Vanessa Tamas,
  • Erlinda R. Ulloa,
  • Monika Kumaraswamy,
  • Samira Dahesh,
  • Raymond Zurich,
  • Victor Nizet and
  • Alison Coady

18 December 2025

Urinary tract infections (UTIs) are common in children and are predominantly caused by uropathogenic Escherichia coli (UPEC). An increasing proportion of these strains produce extended-spectrum β-lactamases (ESBLs), which render β-lactam an...

  • Review
  • Open Access
466 Views
22 Pages

Recent Advances in Endolysin Engineering

  • Mackenzie Aitken,
  • Gayan Abeysekera,
  • Craig Billington and
  • Renwick C. J. Dobson

18 December 2025

Antimicrobial resistance threatens a new “dark age” in medical practice. Chronic antibiotic overuse has driven the rise in antimicrobial resistance and promoted the emergence of multidrug-resistant organisms. To address this problem, rese...

  • Article
  • Open Access
225 Views
23 Pages

Pathogen-Specific Actinium-225 and Lutetium-177 Labeled Antibodies for Treatment of Biofilm-Associated Implant Infections: Initial In Vivo Proof-of-Concept

  • F. Ruben H. A. Nurmohamed,
  • Kevin J. H. Allen,
  • Mackenzie E. Malo,
  • Connor Frank,
  • J. Fred F. Hooning van Duvenbode,
  • Berend van der Wildt,
  • Alex J. Poot,
  • Marnix G. E. H. Lam,
  • Jos A. G. van Strijp and
  • Peter G. J. Nikkels
  • + 4 authors

18 December 2025

Background: the primary challenge with implant infections is the formation of biofilm, which harbors dormant bacteria that reduce the effectiveness of antibiotics and amplify antibiotic resistance, exacerbating the global antimicrobial resistance cri...

  • Article
  • Open Access
420 Views
17 Pages

Navigating Antimicrobial Resistance Insights: An In-Depth Analysis of Healthcare Providers’ Knowledge, Attitudes, and Practices, with an Emphasis on Precision Medicine in Pakistan

  • Sidra Shahid,
  • Aiman Athar,
  • Shahzeen Farooq,
  • Madena Yahya,
  • Muhammad Saad Ashraf,
  • Shafaq Mahmood and
  • Abdul Momin Rizwan Ahmad

18 December 2025

Antibiotics play a crucial role in the treatment of many complicated problems in clinical medicine, but antimicrobial resistance (AMR) has emerged as a serious concern threatening to undermine its effectiveness. Precision medicine (PM) which tailors...

  • Article
  • Open Access
303 Views
10 Pages

18 December 2025

Background: The inappropriate and empirical use of antibiotics in early childhood remains a major global public health concern, contributing significantly to the rise of antimicrobial resistance (AMR). In Kosovo, the COVID-19 pandemic further influen...

  • Article
  • Open Access
301 Views
18 Pages

Efficacy of Dual-Antibiotic-Loaded Bone Cement Against Multi-Drug-Resistant Staphylococcus aureus and Enterococcus faecalis in a Galleria mellonella Model of Periprosthetic Joint Infection

  • You Zhao,
  • Gopala Krishna Mannala,
  • Raphaëlle Youf,
  • Martina Humez,
  • Ruth Schewior,
  • Klaus-Dieter Kühn,
  • Volker Alt and
  • Martijn Riool

17 December 2025

Background: Antibiotic-loaded bone cement (ALBC) is widely used for local antibiotic delivery in joint arthroplasty to prevent and treat prosthetic joint infections (PJIs). In this study, we evaluated the efficacy of cemented Kirschner (K)-wires coat...

  • Review
  • Open Access
516 Views
25 Pages

Antibiotic Prophylaxis and Postoperative Therapy in Tooth Extractions for Patients at Risk of Medication-Related Osteonecrosis of the Jaw (MRONJ): A Scoping Review

  • Selene Barone,
  • Alessandro Antonelli,
  • Antonio Madonna,
  • Amerigo Giudice,
  • Massimo Borelli and
  • Francesco Bennardo

17 December 2025

Background/Objectives: Although several studies have reported antibiotic protocols for the prevention of medication-related osteonecrosis of the jaw (MRONJ) in patients receiving antiresorptive and/or antiangiogenic therapy following tooth extraction...

  • Article
  • Open Access
328 Views
14 Pages

Occurrence of Virulence and Antibiotic Resistance in Pseudomonas aeruginosa Isolated from the Environmental Water from Tamaulipas, Mexico

  • Jessica I. Licea-Herrera,
  • Abraham Guerrero,
  • Paulina Guel,
  • Virgilio Bocanegra-García,
  • Gildardo Rivera and
  • Ana Verónica Martínez-Vázquez

17 December 2025

Background/Objectives: Antibiotic-resistant strains have been reported in aquatic ecosystems, with varying prevalence and resistance patterns by region. In Tamaulipas, Mexico, little information has been generated on this topic, making it difficult t...

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Antibiotics - ISSN 2079-6382