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Biosensors, Volume 11, Issue 8

August 2021 - 49 articles

Cover Story: Point-of-care monitoring of hydrogen peroxide is important due to its wide usage in biomedicine, households and industry. Wei and co-authors from Xi’an Jiaotong University have developed a paper sensor for sensitive, visual and selective detection of H2O2 using mesoporous metal oxide hollow spheres as a nanozyme. The obtained paper sensor can be effectively used for detection of H2O2 in the range of 2.4–150 µM. This work provides a low-cost paper sensor fabricated from a mesoporous metal oxide nanozyme. These sensors could be potentially used in bioanalysis, food security and environmental protection. View this paper.
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Articles (49)

  • Review
  • Open Access
40 Citations
13,025 Views
22 Pages

Spectrophotometric Assays for Sensing Tyrosinase Activity and Their Applications

  • Yu-Fan Fan,
  • Si-Xing Zhu,
  • Fan-Bin Hou,
  • Dong-Fang Zhao,
  • Qiu-Sha Pan,
  • Yan-Wei Xiang,
  • Xing-Kai Qian,
  • Guang-Bo Ge and
  • Ping Wang

23 August 2021

Tyrosinase (TYR, E.C. 1.14.18.1), a critical enzyme participating in melanogenesis, catalyzes the first two steps in melanin biosynthesis including the ortho-hydroxylation of L-tyrosine and the oxidation of L-DOPA. Previous pharmacological investigat...

  • Review
  • Open Access
44 Citations
7,750 Views
26 Pages

Electroanalytical Overview: Electrochemical Sensing Platforms for Food and Drink Safety

  • Alejandro Garcia-Miranda Ferrari,
  • Robert D. Crapnell and
  • Craig E. Banks

23 August 2021

Robust, reliable, and affordable analytical techniques are essential for screening and monitoring food and water safety from contaminants, pathogens, and allergens that might be harmful upon consumption. Recent advances in decentralised, miniaturised...

  • Review
  • Open Access
178 Citations
32,931 Views
25 Pages

PDMS Bonding Technologies for Microfluidic Applications: A Review

  • Alexandra Borók,
  • Kristóf Laboda and
  • Attila Bonyár

23 August 2021

This review summarizes and compares the available surface treatment and bonding techniques (e.g., corona triggered surface activation, oxygen plasma surface activation, chemical gluing, and mixed techniques) and quality/bond-strength testing methods...

  • Article
  • Open Access
18 Citations
6,179 Views
10 Pages

A Rapid Single-Cell Antimicrobial Susceptibility Testing Workflow for Bloodstream Infections

  • Britney Forsyth,
  • Peter Torab,
  • Jyong-Huei Lee,
  • Tyler Malcom,
  • Tza-Huei Wang,
  • Joseph C. Liao,
  • Samuel Yang,
  • Erik Kvam,
  • Chris Puleo and
  • Pak Kin Wong

22 August 2021

Bloodstream infections are a significant cause of morbidity and mortality worldwide. The rapid initiation of effective antibiotic treatment is critical for patients with bloodstream infections. However, the diagnosis of bloodborne pathogens is largel...

  • Article
  • Open Access
10 Citations
4,184 Views
13 Pages

Stability Assessment of Four Chimeric Proteins for Human Chagas Disease Immunodiagnosis

  • Paola Alejandra Fiorani Celedon,
  • Leonardo Maia Leony,
  • Ueriton Dias Oliveira,
  • Natália Erdens Maron Freitas,
  • Ângelo Antônio Oliveira Silva,
  • Ramona Tavares Daltro,
  • Emily Ferreira Santos,
  • Marco Aurélio Krieger,
  • Nilson Ivo Tonin Zanchin and
  • Fred Luciano Neves Santos

22 August 2021

The performance of an immunoassay relies on antigen-antibody interaction; hence, antigen chemical stability and structural integrity are paramount for an efficient assay. We conducted a functional, thermostability and long-term stability analysis of...

  • Article
  • Open Access
21 Citations
6,588 Views
13 Pages

In Vitro Anticancer Drug Sensitivity Sensing through Single-Cell Raman Spectroscopy

  • Jingkai Wang,
  • Kaicheng Lin,
  • Huijie Hu,
  • Xingwang Qie,
  • Wei E. Huang,
  • Zhisong Cui,
  • Yan Gong and
  • Yizhi Song

20 August 2021

Traditional in vitro anticancer drug sensitivity testing at the population level suffers from lengthy procedures and high false positive rates. To overcome these defects, we built a confocal Raman microscopy sensing system and proposed a single-cell...

  • Article
  • Open Access
12 Citations
4,129 Views
15 Pages

Developing Activated Carbon Veil Electrode for Sensing Salivary Uric Acid

  • Maria A. Bukharinova,
  • Natalia Yu. Stozhko,
  • Elizaveta A. Novakovskaya,
  • Ekaterina I. Khamzina,
  • Aleksey V. Tarasov and
  • Sergey V. Sokolkov

20 August 2021

The paper describes the development of a carbon veil-based electrode (CVE) for determining uric acid (UA) in saliva. The electrode was manufactured by lamination technology, electrochemically activated and used as a highly sensitive voltammetric sens...

  • Review
  • Open Access
27 Citations
6,151 Views
17 Pages

Recent Progress of SERS Nanoprobe for pH Detecting and Its Application in Biological Imaging

  • Lei Zhang,
  • Qianqian Zhao,
  • Zhitao Jiang,
  • Jingjing Shen,
  • Weibing Wu,
  • Xingfen Liu,
  • Quli Fan and
  • Wei Huang

19 August 2021

As pH value almost affects the function of cells and organisms in all aspects, in biology, biochemical and many other research fields, it is necessary to apply simple, intuitive, sensitive, stable detection of pH and base characteristics inside and o...

  • Article
  • Open Access
12 Citations
4,770 Views
10 Pages

Color-Coded Droplets and Microscopic Image Analysis for Multiplexed Antibiotic Susceptibility Testing

  • Yunjin Jeong,
  • Haewook Jang,
  • Junwon Kang,
  • Juhong Nam,
  • Kyoungseob Shin,
  • Sunghoon Kwon and
  • Jungil Choi

19 August 2021

Since the discovery of antibiotics, the emergence of antibiotic resistance has become a global issue that is threatening society. In the era of antibiotic resistance, finding the proper antibiotics through antibiotic susceptibility testing (AST) is c...

  • Article
  • Open Access
11 Citations
3,905 Views
17 Pages

19 August 2021

This work demonstrates the analysis of epinephrine (EP) and uric acid (UA) in a single drop (the volume of the test solution was only 50 µL) using a screen-printed carbon electrode (SPCE) sensor and square-wave voltammetry (SWV). The limit of detecti...

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Biosensors - ISSN 2079-6374