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Journal of Clinical Medicine, Volume 8, Issue 1

January 2019 - 127 articles

Cover Story: Recently, research topics and clinical issues have shifted risk factors for Internet gaming disorder (IGD) to protective factors for the disorder, with the aim of preventing its occurrence and aiding the recovery of IGD patients. Despite the importance of the resilience for preventing IGD, there is a lack of research investigating the relationship between resilience and IGD, and, importantly, the precise neural correlates and/or contributors of resilience remain largely unknown. The following paper will discuss the neurophysiological features of individuals with IGD and their relationship with resilience by resting-state electroencephalography (EEG) connectivity. By investigating the neurophysiological mechanism among IGD patients, clinical symptoms, and resilience, it may help clinicians to obtain a new perspective for understanding IGD and establish effective preventions of IGD. View this paper
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Articles (127)

  • Article
  • Open Access
18 Citations
5,723 Views
11 Pages

Application of a Perception Neuron® System in Simulation-Based Surgical Training

  • Hyun Soo Kim,
  • Nhayoung Hong,
  • Myungjoon Kim,
  • Sang Gab Yoon,
  • Hyeong Won Yu,
  • Hyoun-Joong Kong,
  • Su-Jin Kim,
  • Young Jun Chai,
  • Hyung Jin Choi and
  • June Young Choi
  • + 3 authors

21 January 2019

While multiple studies show that simulation methods help in educating surgical trainees, few studies have focused on developing systems that help trainees to adopt the most effective body motions. This is the first study to use a Perception Neuron&re...

  • Article
  • Open Access
18 Citations
4,513 Views
12 Pages

Total Reference Air Kerma is Associated with Late Bowel Morbidity in Locally Advanced Cervical Cancer Patients Treated with Image-Guided Adaptive Brachytherapy

  • Sophie Bockel,
  • Alexandre Escande,
  • Isabelle Dumas,
  • Elena Manea,
  • Philippe Morice,
  • Sebastien Gouy,
  • Eric Deutsch,
  • Christine Haie-Meder and
  • Cyrus Chargari

21 January 2019

No dose volume parameter has been identified to predict late bowel toxicities in locally advanced cervical cancer (LACC) patients treated with image-guided adaptive brachytherapy. We examined the incidence of bowel toxicities according to the total r...

  • Article
  • Open Access
33 Citations
5,959 Views
14 Pages

Evidence for a Common Genetic Origin of Classic and Milder Adult-Onset Forms of Isolated Hypogonadotropic Hypogonadism

  • Biagio Cangiano,
  • Paolo Duminuco,
  • Valeria Vezzoli,
  • Fabiana Guizzardi,
  • Iacopo Chiodini,
  • Giovanni Corona,
  • Mario Maggi,
  • Luca Persani and
  • Marco Bonomi

21 January 2019

Multiple metabolic and inflammatory mechanisms are considered the determinants of acquired functional isolated hypogonadotropic hypogonadism (IHH) in males, whereas classic IHH is a rare congenital condition with a strong genetic background. Since we...

  • Article
  • Open Access
54 Citations
6,245 Views
13 Pages

Glutathione Metabolism, Mitochondria Activity, and Nitrosative Stress in Patients Treated for Mandible Fractures

  • Jan Borys,
  • Mateusz Maciejczyk,
  • Bożena Antonowicz,
  • Adam Krętowski,
  • Jarosław Sidun,
  • Emilia Domel,
  • Jan Ryszard Dąbrowski,
  • Jerzy Robert Ładny,
  • Katarzyna Morawska and
  • Anna Zalewska

21 January 2019

The aim of the study was to evaluate the effect of titanium bone fixations on mitochondrial activity, reactive oxygen species (ROS) production, glutathione metabolism, and selected markers of oxidative/nitrosative stress in the periosteum-like tissue...

  • Article
  • Open Access
6 Citations
12,376 Views
13 Pages

20 January 2019

This study aimed to explore the associations of piracetam use and the clinical characteristics of NIHSS (National Institute of Health Stroke Scale) changes—the importance of which, as prognosis related factors, was previously unnoticed—an...

  • Case Report
  • Open Access
13 Citations
6,235 Views
12 Pages

Dialysis or a Plant-Based Diet in Advanced CKD in Pregnancy? A Case Report and Critical Appraisal of the Literature

  • Rossella Attini,
  • Benedetta Montersino,
  • Filomena Leone,
  • Fosca Minelli,
  • Federica Fassio,
  • Maura Maria Rossetti,
  • Loredana Colla,
  • Bianca Masturzo,
  • Antonella Barreca and
  • Guido Menato
  • + 1 author

20 January 2019

Pregnancy is increasingly reported in chronic kidney disease (CKD), reflecting higher awareness, improvements in materno-foetal care, and a more flexible attitude towards “allowing” pregnancy in the advanced stages of CKD. Success is not...

  • Article
  • Open Access
14 Citations
4,368 Views
11 Pages

Clinical and Rehabilitative Predictors of Peak Oxygen Uptake Following Cardiac Transplantation

  • Katelyn E. Uithoven,
  • Joshua R. Smith,
  • Jose R. Medina-Inojosa,
  • Ray W. Squires,
  • Erik H. Van Iterson and
  • Thomas P. Olson

19 January 2019

The measurement of peak oxygen uptake (VO2peak) is an important metric for evaluating cardiac transplantation (HTx) eligibility. However, it is unclear which factors (e.g., recipient demographics, clinical parameters, cardiac rehabilitation (CR) part...

  • Review
  • Open Access
46 Citations
6,044 Views
13 Pages

19 January 2019

Autoreactive CD4+ T cells, which target antigens in central nervous system (CNS) myelin, are widely believed to play a critical role in the pathogenesis of multiple sclerosis (MS) in concert with other immune effectors. This theory is supported by da...

  • Article
  • Open Access
62 Citations
7,483 Views
11 Pages

Homocysteine: A Potential Biomarker for Diabetic Retinopathy

  • Amany Tawfik,
  • Riyaz Mohamed,
  • Nehal M. Elsherbiny,
  • Margaret M. DeAngelis,
  • Manuela Bartoli and
  • Mohamed Al-Shabrawey

19 January 2019

Diabetic retinopathy (DR) is the most common cause of blindness in people under the age of 65. Unfortunately, the current screening process for DR restricts the population that can be evaluated and the disease goes undetected until irreversible damag...

  • Article
  • Open Access
9 Citations
4,535 Views
11 Pages

Molecular Profile of Advanced Non-Small Cell Lung Cancers in Octogenarians: The Door to Precision Medicine in Elderly Patients

  • Caterina Fumagalli,
  • Chiara Catania,
  • Alberto Ranghiero,
  • Carlo Bosi,
  • Giuseppe Viale,
  • Filippo de Marinis,
  • Massimo Barberis and
  • Elena Guerini-Rocco

18 January 2019

Background: There is a pressing need to expand the evidence base in geriatric lung oncology. Most non-small cell lung cancers (NSCLCs) are diagnosed in the elderly, with approximately 15% of cases affecting octogenarians. Treatment-related decisions...

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J. Clin. Med. - ISSN 2077-0383