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Open AccessArticle

Effect of Size and Location of Nevi on Postoperative Pain and Emergence Agitation in Children Undergoing Nevi Excision

1
Department of Anesthesiology and Pain Medicine, Ajou University School of Medicine, Suwon 164, Korea
2
Biostatistics Collaboration Unit, Yonsei University College of Medicine, Seoul 03722, Korea
3
Department of Plastic and Reconstructive Surgery, Ajou University School of Medicine, Suwon 164, Korea
*
Author to whom correspondence should be addressed.
J. Clin. Med. 2019, 8(1), 106; https://doi.org/10.3390/jcm8010106
Received: 21 December 2018 / Revised: 15 January 2019 / Accepted: 16 January 2019 / Published: 17 January 2019
(This article belongs to the Special Issue Management of Postoperative Pain)
Congenital melanocytic nevi need surgical excisions. However, the effect of the size and location of the nevi on pain and emergence agitation have yet to be studied. The objective of this study was to evaluate (1) the ideal parameter of the nevus size and (2) the effects of the size and location of the nevus on pain and emergence agitation. This observational study enrolled 100 children scheduled for an excision of a nevus under sevoflurane anesthesia. The parameters of the nevus size included the long diameter, the area before resection, the area of resection, and the proportion (the area of resection/total body surface). The nevus locations included the trunk, face, scalp, and extremities. The proportion of the nevi was the most ideal parameter in evaluating the pain and emergence agitation. A large size showed a higher emergence agitation than a small size (median (range); 6 (0–20) in small groups vs. 12.5 (0–20) in large groups, p = 0.021). However, the pain was comparable. The nevus location did not influence pain or emergence agitation. In a multivariate regression analysis, a younger age and an extensive excision were associated with higher pain and emergence agitation. In conclusion, large nevi induced more severe emergence agitation. However, the nevus location did not affect the outcome. In addition, a younger age was associated with pain and emergence agitation. Clinicians need to consider the proportion of nevi when managing children undergoing a nevus excision. View Full-Text
Keywords: child; emergence agitation; nevi; pain child; emergence agitation; nevi; pain
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MDPI and ACS Style

Kim, J.-S.; Lee, H.S.; Park, D.H.; Seok, S.; Kim, T.K.; Lee, H.S.; Kim, J.E. Effect of Size and Location of Nevi on Postoperative Pain and Emergence Agitation in Children Undergoing Nevi Excision. J. Clin. Med. 2019, 8, 106.

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