Special Issue "Clinical, Epidemiologic and Translational Studies of Sepsis and Septic Shock"
Deadline for manuscript submissions: 5 June 2019
Sepsis is a very complex and dynamic syndrome defined as a dysregulated host response to an infection but manifests as a complex infectious and immunological disorder. At present, over 20 million people are estimated to suffer from sepsis worldwide every year, where 6 million die in hospitals and another 5 million die within a year. There is a lack of early diagnostic tools and also novel non-antibiotic therapies. Also, in recent years it has become increasingly evident that sepsis survivors suffer serious negative long-term consequences. Sepsis results in massive activation of the host immune defense system both from innate and adaptive immune system. However, the sepsis can vary widely over the course of the infection and the molecular response in sepsis may be highly specific to individuals or group of individuals as a result of several factors such as i) different infecting pathogens, ii) different sites of infection, iii) host phenotypes such as gender, age, comorbidities, genetic predisposition, and iv) stage or time point of the pro- or anti-inflammatory cascades. Further understanding of the epidemiology and pathophysiology of sepsis is essential for development of diagnostic tools and novel treatment options.
Please join us in presenting this Special Issue that reveals novel evidence of sepsis epidemiology, pathophysiology, diagnostic tools, treatments and long-term consequences.
Prof. Adam Linder
Prof. Konrad Reinhart
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1800 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- Septic shock
- Organ failure
- Immune system