Special Issue "Testosterone and Men’s Health: From Evidence to Clinical Practice"
Deadline for manuscript submissions: closed (28 February 2019) | Viewed by 38976
Interests: sexual function in men and women; men’s health and TRT; nocturia; laser in prostate and endoscopic surgery; regenerative medicine
Interests: male sexual health and dysfunction; male infertility; hormonal regulation of male reproduction and hypogonadism; prostate diseases and male voiding dysfunctions; healthy aging and anti-aging treatments
Since the personal expert opinion of Dr. Morales in 1996, ‘Clinical practice guidelines for screening and monitoring male patients receiving testosterone supplementation therapy’ in the treatment of ED, great amount of new informations has been accumulated for the management of androgen deficiency, traditionally, most testosterone replacement has been applied for primary hypogonadism. Recently, TRT (Testosterone Replacement Therapy) has been increased from the development of safe, effective non-alkylated preparations and increased life expectancy with secondary hypogonadism of LOH (Late Onset Hypogonadism). From the first official recommendations of ISSAM 2002, the official recommendations on the diagnosis, treatment and monitoring of hypogonadism in men has evolved due to there being more evidence. ISSAM released updates in 2004, 2008 and 2014 in conjunction with ISA (International Society for Andrology), EAU (European Association of Urology), EAA (European Association of Andrology) and ASA (American Society for Andrology).
The diagnosis of late-onset testosterone deficiency is based on the presence of symptoms or signs and persistent low serum testosterone levels. However, we still do not have accurate measurement of serum testosterone level and no diagnostic questionnaire. Furthermore, safety concerns of TRT regarding the prostate and cardiovascular system are problematic. The benefits and risks of testosterone therapy must be clearly discussed with the patient and assessment of prostate and other risk factors considered before commencing testosterone treatment. Response to testosterone treatment should be assessed. If there is no improvement of symptoms and signs, treatment should be withdrawn and the patient investigated for other possible causes of the clinical presentations.
Clinically, urologists are at the center of TRT due to the closer association of sexual symptoms with testosterone and concern of prostate safety after TRT. We should recognize the differences between endocrinological and uroandrological points of view, and be more interested in the systemic manifestation of TRT for better clinical practice in the era of men’s health.
The following topics will be discussed in our special issue:
Testosterone and Insulin Resistance, Diabetes
Testosterone and Brain, Cognitive Function
Testosterone and Physical Performance
Testosterone and Bone Metabolism
Testosterone and Lipid Metabolism
Optimal Indication of Testosterone Replacement Therapy?
How to Select Optimal Regimen for Testosterone Replacement Therapy?
Emerging Evidences in Long Standing Controversies about Testosterone Replacement Therapy
(I) Cardiovascular Issues
(II) Prostate Issues
What is the Goal of TRT: Testosterone Level or Symptom?
Evolving Concept of TRT Guideline
Prof. Dr. Du Geon Moon
Prof. Dr. Hyun Jun Park
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- Testosterone replacement
- Late onset hypogonadism
- Cardiovascular disease