The New Frontier in Pulmonary Fibrosis

Dear Colleagues,

As you are aware, idiopathic pulmonary fibrosis (IPF) is an unrelenting and incurable disease characterized primarily by progressive stiffening and scarring of the lungs. In IPF, alveolar epithelial cell dysfunction and aberrant proliferation of activated fibroblasts—with contemporaneous vascular endothelial cell dysfunction—contribute to the development of alveolar thickening, which then leads to the formation of fibroblastic foci and the honeycombing of the lungs and, ultimately, respiratory failure and death.  This Special Issue focuses on novel mechanisms, diagnostic techniques, and therapeutics contributing to IPF, including aberrant metabolic and immunologic responses to lung tissue regeneration, as well as frequent comorbidities seen in IPF such as pulmonary hypertension. We warmly welcome a broad assortment of submissions, including original papers and reviews, on the forefront of this stimulating topic.

Dr. Andrew J. Bryant
Guest Editor

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