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Journal of Clinical Medicine, Volume 11, Issue 1

January-1 2022 - 282 articles

Cover Story: A series of global mechanisms contribute to systemic iron deficiency in heart failure and its consequences. The causes can be divided into the reduced intake, decreased absorption, and increased loss of iron. Reduced intake could be due to decreased absolute amounts of iron or low iron bioavailability. Reduced absorption is thought to be due to intestinal oedema, increased intestinal pH, increased hepcidin levels, and intestinal hypoperfusion, among others. Increased losses are mainly due to gastro-intestinal bleeding. Iron deficiency results in reduced organ function of the heart and skeletal muscles, anaemia, impaired immune responses, deranged metabolism, and kidney injury. Iron deficiency is associated with impaired exercise tolerance, increased heart failure hospitalisations, and mortality. View this paper
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Articles (282)

  • Article
  • Open Access
11 Citations
3,313 Views
15 Pages

Plasma microRNA-320a as a Potential Biomarker of Physiological Changes during Training in Professional Volleyball Players

  • Rafał Podgórski,
  • Marek Cieśla,
  • Dominika Podgórska,
  • Wojciech Bajorek,
  • Artur Płonka,
  • Wojciech Czarny,
  • Robert Trybulski and
  • Paweł Król

5 January 2022

A deeper insight into the mechanisms responsible for athlete performance that may serve as specific and detailed training indicators is still desired, because conventionally used biomarkers provide limited information about the adaptive processes tha...

  • Article
  • Open Access
2 Citations
2,823 Views
12 Pages

5 January 2022

The braces of today are constructed to correct the frontal plane deformity of idiopathic adolescent scoliosis (AIS). The Spinaposture brace© (Spinaposture Aps, Copenhagen, Denmark) is a soft-fabric brace for AIS and is designed to enhance rotati...

  • Review
  • Open Access
16 Citations
5,748 Views
13 Pages

Optical Coherence Tomography—OCT for Characterization of Non-Atherosclerotic Coronary Lesions in Acute Coronary Syndromes

  • Mihail Spînu,
  • Laurenţiu Horea Onea,
  • Călin Homorodean,
  • Maria Olinic,
  • Mihai Claudiu Ober and
  • Dan Mircea Olinic

5 January 2022

Cardiovascular diseases are the main cause of death worldwide, with coronary artery disease being the predominant underlying etiology. The most prevalent coronary lesions are represented by the atherosclerotic plaques, in more than 85% of cases, but...

  • Review
  • Open Access
178 Citations
17,442 Views
14 Pages

Cognitive Impairment in People with Epilepsy

  • Ajda Novak,
  • Karmen Vizjak and
  • Martin Rakusa

5 January 2022

People with epilepsy frequently have cognitive impairment. The majority of cognitive problems is influenced by a variety of interlinked factors, including the early onset of epilepsy and the frequency, intensity and duration of seizures, along with t...

  • Article
  • Open Access
12 Citations
4,634 Views
10 Pages

Risk Factors Associated with Mortality in Severe Chest Trauma Patients Admitted to the ICU

  • Jesús Abelardo Barea-Mendoza,
  • Mario Chico-Fernández,
  • Manuel Quintana-Díaz,
  • Jon Pérez-Bárcena,
  • Luís Serviá-Goixart,
  • Ismael Molina-Díaz,
  • María Bringas-Bollada,
  • Antonio Luis Ruiz-Aguilar,
  • María Ángeles Ballesteros-Sanz and
  • Juan Antonio Llompart-Pou
  • + 1 author

5 January 2022

Our objective was to determine outcomes of severe chest trauma admitted to the ICU and the risk factors associated with mortality. An observational, prospective, and multicenter registry of trauma patients admitted to the participating ICUs (March 20...

  • Article
  • Open Access
9 Citations
2,201 Views
11 Pages

5 January 2022

Background: Pseudoexfoliation syndrome (PEX) is a systemic, age-related disorder characterized by the production and accumulation of pseudoexfoliation material. To date, detailed characteristics have not been published regarding the iridocorneal angl...

  • Review
  • Open Access
52 Citations
8,342 Views
12 Pages

Newborn Hearing Screening Benefits Children, but Global Disparities Persist

  • Katrin Neumann,
  • Philipp Mathmann,
  • Shelly Chadha,
  • Harald A. Euler and
  • Karl R. White

5 January 2022

There is substantial evidence that newborn hearing screening (NHS) reduces the negative sequelae of permanent childhood hearing loss (PCHL) if performed in programs that aim to screen all newborns in a region or nation (often referred to as Universal...

  • Article
  • Open Access
14 Citations
5,933 Views
13 Pages

Effectiveness of Therapeutic Exercise and Patient Education on Cancer-Related Fatigue in Breast Cancer Survivors: A Randomised, Single-Blind, Controlled Trial with a 6-Month Follow-Up

  • Virginia Prieto-Gómez,
  • María José Yuste-Sánchez,
  • Javier Bailón-Cerezo,
  • Helena Romay-Barrero,
  • Irene de la Rosa-Díaz,
  • Cristina Lirio-Romero and
  • María Torres-Lacomba

5 January 2022

This study aimed to determine the effectiveness of therapeutic exercise plus patient therapeutic education on perceived fatigue, functional capacity and pain in breast cancer survivors with cancer-related fatigue. A randomised, single-blind, clinical...

  • Article
  • Open Access
5 Citations
3,008 Views
9 Pages

5 January 2022

Dyslipidaemia is a well-known risk factor for coronary artery disease (CAD), and reducing lipid levels is essential for secondary prevention in management of these high-risk individuals. Dyslipidaemia is common also in patients with obstructive sleep...

  • Article
  • Open Access
21 Citations
3,955 Views
23 Pages

5 January 2022

While paresthesia-based Spinal Cord Stimulation (SCS) has been proven effective as treatment for chronic neuropathic pain, its initial benefits may lead to the development of “Failed SCS Syndrome’ (FSCSS) defined as decrease over time rel...

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J. Clin. Med. - ISSN 2077-0383