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Review

Optical Coherence Tomography—OCT for Characterization of Non-Atherosclerotic Coronary Lesions in Acute Coronary Syndromes

1
Medical Clinic Number 1, “Iuliu Haţieganu” University of Medicine and Pharmacy, 400006 Cluj-Napoca, Romania
2
Department of Interventional Cardiology, Cluj County Emergency Hospital, 400006 Cluj-Napoca, Romania
*
Author to whom correspondence should be addressed.
These authors contribution is equally to this work.
Academic Editor: Manuel Martínez-Sellés
J. Clin. Med. 2022, 11(1), 265; https://doi.org/10.3390/jcm11010265
Received: 29 November 2021 / Revised: 20 December 2021 / Accepted: 2 January 2022 / Published: 5 January 2022
(This article belongs to the Special Issue Advances in the Diagnosis and Treatment of Coronary Artery Disease)
Cardiovascular diseases are the main cause of death worldwide, with coronary artery disease being the predominant underlying etiology. The most prevalent coronary lesions are represented by the atherosclerotic plaques, in more than 85% of cases, but there are several other non-atherosclerotic lesions such as spontaneous coronary artery dissection and/or hematoma and spontaneous recanalization of coronary thrombus, which are less common, approximately 5% of cases, but with similar clinical manifestations as well as complications. There are insufficient data regarding the pathological mechanism, true prevalence and optimal treatment of these kind of coronary lesions. Optical coherence tomography (OCT) is an intracoronary imaging technique, developed in order to overcome the diagnostic limitations of a standard coronary angiography and has an extremely high resolution, similar to that of a usual histological evaluation of a biopsy sample, thus, OCT provides a histological-like information, but in a in vivo environment. The aim of this article is to review the current knowledge regarding non-atherosclerotic coronary lesions, with an emphasis on the importance of OCT for optimal identification, characterization of pathogenic mechanisms and optimal treatment selection. View Full-Text
Keywords: non-atherosclerotic coronary lesions; spontaneous coronary artery dissection; spontaneous recanalization of coronary thrombus; acute coronary syndromes; optical coherence tomography non-atherosclerotic coronary lesions; spontaneous coronary artery dissection; spontaneous recanalization of coronary thrombus; acute coronary syndromes; optical coherence tomography
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MDPI and ACS Style

Spînu, M.; Onea, L.H.; Homorodean, C.; Olinic, M.; Ober, M.C.; Olinic, D.M. Optical Coherence Tomography—OCT for Characterization of Non-Atherosclerotic Coronary Lesions in Acute Coronary Syndromes. J. Clin. Med. 2022, 11, 265. https://doi.org/10.3390/jcm11010265

AMA Style

Spînu M, Onea LH, Homorodean C, Olinic M, Ober MC, Olinic DM. Optical Coherence Tomography—OCT for Characterization of Non-Atherosclerotic Coronary Lesions in Acute Coronary Syndromes. Journal of Clinical Medicine. 2022; 11(1):265. https://doi.org/10.3390/jcm11010265

Chicago/Turabian Style

Spînu, Mihail, Laurenţiu Horea Onea, Călin Homorodean, Maria Olinic, Mihai Claudiu Ober, and Dan Mircea Olinic. 2022. "Optical Coherence Tomography—OCT for Characterization of Non-Atherosclerotic Coronary Lesions in Acute Coronary Syndromes" Journal of Clinical Medicine 11, no. 1: 265. https://doi.org/10.3390/jcm11010265

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