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Antioxidants, Volume 9, Issue 6

June 2020 - 105 articles

Cover Story: Anthocyanins are natural colorants with antioxidant properties and have been shown to inhibit photoaging reactions and reduce the symptoms of some skin diseases. We investigated their ability to penetrate the stratum corneum, a prerequisite for bioactivity in the skin when used in a lipstick formulation. Simple and complex anthocyanins were able to permeate through the stratum corneum in vivo and reach depths relevant for their use as beneficial ingredients in skin care products. This work provides insight on the permeation behavior of different anthocyanins through the skin, demonstrating both lateral and transversal diffusion when applied topically in a lipophilic delivery system. These findings further contribute to the understanding of anthocyanin delivery in other topical formulations. View this paper.
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Articles (105)

  • Article
  • Open Access
20 Citations
5,059 Views
16 Pages

The Hypoxia Tolerance of the Goldfish (Carassius auratus) Heart: The NOS/NO System and Beyond

  • Mariacristina Filice,
  • Rosa Mazza,
  • Serena Leo,
  • Alfonsina Gattuso,
  • Maria Carmela Cerra and
  • Sandra Imbrogno

The extraordinary capacity of the goldfish (Carassius auratus) to increase its cardiac performance under acute hypoxia is crucial in ensuring adequate oxygen supply to tissues and organs. However, the underlying physiological mechanisms are not yet c...

  • Article
  • Open Access
42 Citations
8,409 Views
16 Pages

Biochemical Characterization of Traditional Varieties of Sweet Pepper (Capsicum annuum L.) of the Campania Region, Southern Italy

  • Florinda Fratianni,
  • Antonio d’Acierno,
  • Autilia Cozzolino,
  • Patrizia Spigno,
  • Riccardo Riccardi,
  • Francesco Raimo,
  • Catello Pane,
  • Massimo Zaccardelli,
  • Valentina Tranchida Lombardo and
  • Marina Tucci
  • + 3 authors

Bioactive compounds of different Campania native sweet pepper varieties were evaluated. Polyphenols ranged between 1.37 mmol g−1 and 3.42 mmol g−1, β-carotene was abundant in the red variety “Cazzone” (7.05 μg g−...

  • Article
  • Open Access
24 Citations
4,773 Views
15 Pages

The aim of this work was to determine the physicochemical and biological activities of hydrolyzed proteins from sonicated oat brans. In addition to the control bran sample, two types of pre-treatment procedures—namely, ultrasonic bath and probe...

  • Article
  • Open Access
56 Citations
12,883 Views
12 Pages

Fresh sprouts are an important source of antioxidant compounds and contain useful phytonutrients in the human diet. Many factors, such as the time of germination and types of light, influence the physiological processes and biosynthetic pathways in s...

  • Review
  • Open Access
59 Citations
7,934 Views
23 Pages

Update on the Effects of Antioxidants on Diabetic Retinopathy: In Vitro Experiments, Animal Studies and Clinical Trials

  • Jose Javier Garcia-Medina,
  • Elena Rubio-Velazquez,
  • Elisa Foulquie-Moreno,
  • Ricardo P Casaroli-Marano,
  • Maria Dolores Pinazo-Duran,
  • Vicente Zanon-Moreno and
  • Monica del-Rio-Vellosillo

Current therapies for diabetic retinopathy (DR) incorporate blood glucose and blood pressure control, vitrectomy, photocoagulation, and intravitreal injections of anti-vascular endothelial growth factors or corticosteroids. Nonetheless, these techniq...

  • Article
  • Open Access
20 Citations
5,327 Views
19 Pages

Vitamin D3 Supplementation in Drinking Water Prior to Slaughter Improves Oxidative Status, Physiological Stress, and Quality of Pork

  • Ana I. Rey,
  • José Francisco Segura,
  • David Castejón,
  • Encarnación Fernández-Valle,
  • Mª Isabel Cambero and
  • Luis Calvo

The aims of this study were to investigate the effect of vitamin D3 administration in drinking water during lairage time prior to slaughter on physiological stress, oxidative status, and pork quality characteristics. Two experiments were carried out....

  • Article
  • Open Access
23 Citations
4,783 Views
11 Pages

Platelet-Rich Fibrin Can Neutralize Hydrogen Peroxide-Induced Cell Death in Gingival Fibroblasts

  • Zahra Kargarpour,
  • Jila Nasirzade,
  • Francesca Di Summa,
  • Layla Panahipour,
  • Richard J. Miron and
  • Reinhard Gruber

Hydrogen peroxide is a damage signal at sites of chronic inflammation. The question arises whether platelet-rich fibrin (PRF), platelet-poor plasma (PPP), and the buffy coat can neutralize hydrogen peroxide toxicity and thereby counteract local oxida...

  • Article
  • Open Access
55 Citations
4,612 Views
16 Pages

Oxidative stress (OS) appears to be an important determinant during the different stages of progression of Alzheimer’s Disease (AD). In particular, impaired antioxidant defense mechanisms, such as the decrease of glutathione (GSH) and nuclear f...

  • Article
  • Open Access
28 Citations
7,457 Views
17 Pages

Plant-Derived Natural Biomolecule Picein Attenuates Menadione Induced Oxidative Stress on Neuroblastoma Cell Mitochondria

  • Kavindra Kumar Kesari,
  • Anupam Dhasmana,
  • Shruti Shandilya,
  • Neeraj Prabhakar,
  • Ahmed Shaukat,
  • Jinze Dou,
  • Jessica M. Rosenholm,
  • Tapani Vuorinen and
  • Janne Ruokolainen

Several bioactive compounds are in use for the treatment of neurodegenerative disorders, such as Alzheimer’s and Parkinson’s disease. Historically, willow (salix sp.) bark has been an important source of salisylic acid and other natural c...

  • Article
  • Open Access
7 Citations
4,682 Views
16 Pages

ApoE Genotype-Dependent Response to Antioxidant and Exercise Interventions on Brain Function

  • Kiran Chaudhari,
  • Jessica M. Wong,
  • Philip H. Vann,
  • Tori Como,
  • Sid E. O’Bryant and
  • Nathalie Sumien

This study determined whether antioxidant supplementation is a viable complement to exercise regimens in improving cognitive and motor performance in a mouse model of Alzheimer’s disease risk. Starting at 12 months of age, separate groups of male and...

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Antioxidants - ISSN 2076-3921