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Antioxidants, Volume 9, Issue 7

July 2020 - 83 articles

Cover Story: Antioxidant organic molecules can be employed as probes for the detection and quantitation of biologically relevant oxidants. Dihydroterphenyl derivatives, with an embedded anthranilate moiety, were studied as fluorescent chemosensors/chemodosimeters in this context. An internal charge transfer (ICT) process in their aromatized derivatives was successfully exploited for the turn-on fluorimetric detection and quantitation of H2O2, a model hydroperoxide and hypochlorite having good analytical figures. The method was also applied in a biological context and in an aqueous environment to quantify glucose by enzymatically coupling its oxidation to H2O2 production. View this paper.
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Articles (83)

  • Article
  • Open Access
10 Citations
4,141 Views
18 Pages

Anti-Inflammatory and Antioxidant Effects of Regular Consumption of Cooked Ham Enriched with Dietary Phenolics in Diet-Induced Obese Mice

  • Antonio Serrano,
  • Antonio González-Sarrías,
  • Francisco A. Tomás-Barberán,
  • Antonio Avellaneda,
  • Amadeo Gironés-Vilaplana,
  • Gema Nieto and
  • Gaspar Ros-Berruezo

Oxidative damage and chronic inflammation have been proven as one of the major factors associated with obesity, which increases the incidence of non-communicable chronic diseases. In this sense, the development of new functional products aiming at th...

  • Article
  • Open Access
27 Citations
5,059 Views
15 Pages

The Interaction between Mitochondrial Oxidative Stress and Gut Microbiota in the Cardiometabolic Consequences in Diet-Induced Obese Rats

  • Adriana Ortega-Hernández,
  • Ernesto Martínez-Martínez,
  • Ruben Gómez-Gordo,
  • Natalia López-Andrés,
  • Amaya Fernández-Celis,
  • Beatriz Gutiérrrez-Miranda,
  • María Luisa Nieto,
  • Teresa Alarcón,
  • Claudio Alba and
  • Dulcenombre Gómez-Garre
  • + 1 author

Background: The objective of this study is to determine the role of mitochondrial oxidative stress in the dysbiosis associated with a high fat diet in rats. In addition, the impact of gut microbiota (GM) in the cardiometabolic consequences of diet-in...

  • Review
  • Open Access
29 Citations
5,036 Views
20 Pages

Redox Imbalances in Ageing and Metabolic Alterations: Implications in Cancer and Cardiac Diseases. An Overview from the Working Group of Cardiotoxicity and Cardioprotection of the Italian Society of Cardiology (SIC)

  • Valentina Mercurio,
  • Alessandra Cuomo,
  • Christian Cadeddu Dessalvi,
  • Martino Deidda,
  • Daniela Di Lisi,
  • Giuseppina Novo,
  • Roberta Manganaro,
  • Concetta Zito,
  • Ciro Santoro and
  • Pietro Ameri
  • + 4 authors

Metabolic syndrome (MetS) is a well established risk factor for cardiovascular (CV) diseases. In addition, several studies indicate that MetS correlates with the increased risk of cancer in adults. The mechanisms linking MetS and cancer are not fully...

  • Article
  • Open Access
46 Citations
4,678 Views
20 Pages

Brown seaweeds are known to present components with appealing bioactive properties eliciting great interest for industrial applications. However, their lipid content is generally disregarded beyond their fatty acid (FA) composition. This study thorou...

  • Article
  • Open Access
27 Citations
5,632 Views
20 Pages

Aging and Progression of Beta-Amyloid Pathology in Alzheimer’s Disease Correlates with Microglial Heme-Oxygenase-1 Overexpression

  • Cristina Fernández-Mendívil,
  • Miguel A. Arreola,
  • Lindsay A. Hohsfield,
  • Kim N. Green and
  • Manuela G. Lopez

Neuroinflammation and oxidative stress are being recognized as characteristic hallmarks in many neurodegenerative diseases, especially those that portray proteinopathy, such as Alzheimer’s disease (AD). Heme-oxygenase 1 (HO-1) is an inducible e...

  • Article
  • Open Access
50 Citations
6,801 Views
16 Pages

Lycopene Protects against Smoking-Induced Lung Cancer by Inducing Base Excision Repair

  • Junrui Cheng,
  • Baxter Miller,
  • Emilio Balbuena and
  • Abdulkerim Eroglu

Background: Oxidative stress plays a critical role in lung cancer progression. Carotenoids are efficient antioxidants. The objective of this study was to explore the efficacy of all-trans retinoic acid (ATRA) and carotenoids in cigarette smoke-induce...

  • Review
  • Open Access
68 Citations
10,108 Views
22 Pages

Can Meat and Meat-Products Induce Oxidative Stress?

  • Adrián Macho-González,
  • Alba Garcimartín,
  • María Elvira López-Oliva,
  • Sara Bastida,
  • Juana Benedí,
  • Gaspar Ros,
  • Gema Nieto and
  • Francisco José Sánchez-Muniz

High meat and meat-products consumption has been related to degenerative diseases. In addition to their saturated fatty acids and cholesterol contents, oxidation products generated during their production, storage, digestion, and metabolization have...

  • Article
  • Open Access
8 Citations
5,212 Views
14 Pages

Effect of Sechium edule var. nigrum spinosum (Chayote) on Telomerase Levels and Antioxidant Capacity in Older Adults with Metabolic Syndrome

  • Graciela Gavia-García,
  • Juana Rosado-Pérez,
  • Itzen Aguiñiga-Sánchez,
  • Edelmiro Santiago-Osorio and
  • Víctor Manuel Mendoza-Núñez

Patients with metabolic syndrome (MetS) have a redox imbalance, due to a decay in antioxidant capacity. Oxidative stress (OxS) is considered an important modulator of telomere shortening and telomerase activity. One of the fruits that has been associ...

  • Review
  • Open Access
49 Citations
11,441 Views
25 Pages

Oxidative stress seems to play a role in many chronic diseases, such as cardiovascular diseases, diabetes, and some cancers. Research is always looking for effective approaches in the prevention and treatment of these pathologies with safe strategies...

  • Review
  • Open Access
41 Citations
13,167 Views
23 Pages

Genetic Polymorphisms Complicate COVID-19 Therapy: Pivotal Role of HO-1 in Cytokine Storm

  • Eddie W. Fakhouri,
  • Stephen J. Peterson,
  • Janish Kothari,
  • Ragin Alex,
  • Joseph I. Shapiro and
  • Nader G. Abraham

Coronaviruses are very large RNA viruses that originate in animal reservoirs and include severe acute respiratory distress syndrome (SARS) and Middle East respiratory syndrome (MERS) and other inconsequential coronaviruses from human reservoirs like...

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Antioxidants - ISSN 2076-3921