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Antioxidants, Volume 8, Issue 11

November 2019 - 63 articles

Cover Story: Overweight and obesity are important risk factors for type 2 diabetes (T2D). Moving towards plant-rich diets increases the intake of bioactive compounds and could decrease the odds of suffering T2D. However, those individuals with high body mass index (BMI) may have altered absorption or metabolism of some nutrients and dietary components, including polyphenols. This work studies whether high dietary intakes of some classes of polyphenols are associated with T2D in a large population with metabolic syndrome and how these associations depend on BMI and sex. View this paper.
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Articles (63)

  • Article
  • Open Access
48 Citations
6,388 Views
20 Pages

From the Field to the Pot: Phytochemical and Functional Analyses of Calendula officinalis L. Flower for Incorporation in an Organic Yogurt

  • Graziela Bragueto Escher,
  • Lorena do Carmo Cardoso Borges,
  • Jânio Sousa Santos,
  • Thiago Mendanha Cruz,
  • Mariza Boscacci Marques,
  • Mariana Araújo Vieira do Carmo,
  • Luciana Azevedo,
  • Marianna M. Furtado,
  • Anderson S. Sant’Ana and
  • Mingchun Wen
  • + 2 authors

15 November 2019

Edible flowers have been used as ingredients because of their biological activities, taste, and overall appearance. This research was aimed to characterize the chemical composition and in vitro antioxidant activity of the marigold flower (Calendula o...

  • Article
  • Open Access
15 Citations
5,461 Views
19 Pages

Penta-1,2,3,4,6-O-Galloyl-β-d-Glucose Inhibits UVB-Induced Photoaging by Targeting PAK1 and JNK1

  • Ji-An Kim,
  • Jae-Eun Lee,
  • Ji Hye Kim,
  • Hyo-Jeong Lee and
  • Nam Joo Kang

15 November 2019

Penta-O-galloyl-β-d-glucose (PGG) is a gallotannin polyphenolic compound that occurs naturally in fermented Rhus verniciflua. The present study aimed to examine the effect of PGG on UVB-induced skin aging and its molecular mechanisms in HaCaT hu...

  • Article
  • Open Access
75 Citations
7,295 Views
16 Pages

15 November 2019

Melanoidins from real foods and model systems have received considerable interest due to potential health benefits. However, due to the complexity of these compounds, to date, the exact structure of melanoidins and mechanism involved in their biologi...

  • Article
  • Open Access
20 Citations
5,280 Views
16 Pages

Novel Polymeric Nanocarriers Reduced Zinc and Doxycycline Toxicity in the Nematode Caenorhabditis elegans

  • Manuel Toledano,
  • Manuel Toledano-Osorio,
  • María D. Navarro-Hortal,
  • Alfonso Varela-López,
  • Raquel Osorio and
  • José L. Quiles

14 November 2019

The objective was to evaluate the toxicity of zinc- and doxycycline-loaded polymeric nanoparticles (NPs) using Caenorhabditis elegans as a model organism. These NPs are composed of ethylene glycol dimethacrylate, 2-hydroxyethyl methacrylate and metha...

  • Article
  • Open Access
24 Citations
5,945 Views
16 Pages

Influence of Cooking and Ingredients on the Antioxidant Activity, Phenolic Content and Volatile Profile of Different Variants of the Mediterranean Typical Tomato Sofrito

  • Ana Beltrán Sanahuja,
  • Saray López De Pablo Gallego,
  • Salvador E. Maestre Pérez,
  • Arantzazu Valdés García and
  • María Soledad Prats Moya

14 November 2019

In this study, six different sofrito formulations were compared with the raw recipe for total phenolic content (TPC), antioxidant activity tested by 2,2-diphenyl-1-picrylhydrazyl (DPPH), ferric-reducing antioxidant power (FRAP) and 2,2-azinobis (3-et...

  • Article
  • Open Access
68 Citations
5,332 Views
15 Pages

Silver Nanoparticles Induce Mitochondrial Protein Oxidation in Lung Cells Impacting Cell Cycle and Proliferation

  • Reetta J. Holmila,
  • Stephen A. Vance,
  • Stephen Bruce King,
  • Allen W. Tsang,
  • Ravi Singh and
  • Cristina M. Furdui

14 November 2019

Silver nanoparticles (AgNPs) are widely used nanomaterials in both commercial and clinical biomedical applications, due to their antibacterial properties. AgNPs are also being explored for the treatment of cancer in particular in combination with ion...

  • Article
  • Open Access
40 Citations
7,139 Views
15 Pages

Piperlongumine Induces Cell Cycle Arrest via Reactive Oxygen Species Accumulation and IKKβ Suppression in Human Breast Cancer Cells

  • Chang Hee Jeong,
  • Haram Ryu,
  • Do Hyun Kim,
  • Wei Nee Cheng,
  • Jee Eun Yoon,
  • Sukyung Kang and
  • Sung Gu Han

14 November 2019

Piperlongumine (PL), a natural product derived from long pepper (Piper longum L.), is known to exhibit anticancer effects. However, the effect of PL on cell cycle-regulatory proteins in estrogen receptor (ER)-positive breast cancer cells is unclear....

  • Article
  • Open Access
52 Citations
7,485 Views
17 Pages

Preparation and Evaluation of Resveratrol-Loaded Composite Nanoparticles Using a Supercritical Fluid Technology for Enhanced Oral and Skin Delivery

  • Eun-Sol Ha,
  • Woo-Yong Sim,
  • Seon-Kwang Lee,
  • Ji-Su Jeong,
  • Jeong-Soo Kim,
  • In-hwan Baek,
  • Du Hyung Choi,
  • Heejun Park,
  • Sung-Joo Hwang and
  • Min-Soo Kim

14 November 2019

We created composite nanoparticles containing hydrophilic additives using a supercritical antisolvent (SAS) process to increase the solubility and dissolution properties of trans-resveratrol for application in oral and skin delivery. Physicochemical...

  • Article
  • Open Access
4 Citations
4,057 Views
12 Pages

Evidence for an Allosteric S-Nitrosoglutathione Binding Site in S-Nitrosoglutathione Reductase (GSNOR)

  • Kathleen Fontana,
  • Nneamaka Onukwue,
  • Bei-Lei Sun,
  • Cristina Lento,
  • Leslie Ventimiglia,
  • Sahar Nikoo,
  • James W. Gauld,
  • Derek J. Wilson and
  • Bulent Mutus

13 November 2019

Current research has identified S-nitrosoglutathione reductase (GSNOR) as the central enzyme for regulating protein S-nitrosylation. In addition, the dysregulation of GSNOR expression is implicated in several organ system pathologies including respir...

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Antioxidants - ISSN 2076-3921