Antioxidant and Anti-inflammatory Properties of Plants Extract

Dear Colleagues,

Inflammation is an adaptive response triggered by noxious stimuli and conditions such as infection and tissue injury. Reactive oxygen and nitrogen species are now acknowledged to play a key role in maintaining normal cellular and tissue physiology but they may start signalling pathways involved in the development of a wide range of inflammation-based degenerative pathologies.

In line with this, numerous phytochemicals with peculiar reducing properties have been recently shown to modulate the inflammatory response effectively. First considered ‘health-promoting’ by virtue of their radical-scavenging activity and/or direct antioxidant effects on cellular biomolecules, such compounds are now believed to be able to interfere with cell signal transduction by intercepting reactive species at the level of critical signalling pathways. In addition, the interaction of these molecules with signalling enzymes, receptors and transcription factors has emerged recently.

Contributions are invited from investigators worldwide in the form of reviews or original research articles on the anti-oxidative and anti-inflammatory effects and mechanisms exerted by plant extracts in vitro and in vivo.

Prof. Mario Allegra
Guest Editor

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