Vol. 15, Iss 6 (Page 2) | JPM

Article

1,213 Views

13 Pages

Guarded Outcomes After Hip Hemiarthroplasty in Patients with Cerebral Palsy: Highlighting a Personalized Medicine Approach to Mitigate the Risk of Complications

Ahmed Nageeb Mahmoud,
Nicholas R. Brule,
Juan D. Bernate,
Mark A. Seeley,
Michael Suk and
Daniel S. Horwitz

J. Pers. Med.2025, 15(6), 252;https://doi.org/10.3390/jpm15060252

15 June 2025

Background: The effectiveness of hip hemiarthroplasty in managing femoral neck fractures in individuals with cerebral palsy has seldom been reported. Objectives: Given the complex neuromuscular issues associated with cerebral palsy (CP), this retrosp...

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Article

2,233 Views

20 Pages

Phenotype-Driven Variability in Longitudinal Body Composition Changes After a Very Low-Calorie Ketogenic Intervention: A Machine Learning Cluster Approach

Victor de la O,
Begoña de Cuevillas,
Miksa Henkrich,
Barbara Vizmanos,
Maitane Nuñez-Garcia,
Ignacio Sajoux,
Daniel de Luis and
J. Alfredo Martínez

J. Pers. Med.2025, 15(6), 251;https://doi.org/10.3390/jpm15060251

14 June 2025

Background: Obesity is a major global public health issue with no fully satisfactory solutions. Most nutritional interventions rely on caloric restriction, with varying degrees of success. Very low-calorie ketogenic diets (VLCKD) have demonstrated ra...

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Article

2 Citations

847 Views

18 Pages

Overcoming Challenges in Learning Prerequisites for Adaptive Functioning: Tele-Rehabilitation for Young Girls with Rett Syndrome

Rosa Angela Fabio,
Samantha Giannatiempo and
Michela Perina

J. Pers. Med.2025, 15(6), 250;https://doi.org/10.3390/jpm15060250

14 June 2025

Background/Objectives: Rett Syndrome (RTT) is a rare neurodevelopmental disorder that affects girls and is characterized by severe motor and cognitive impairments, the loss of purposeful hand use, and communication difficulties. Children with RTT, es...

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Article

945 Views

9 Pages

Tailoring Evaluations of Chronic Rhinosinusitis: Understanding Sleep and Its Effect on Memory Through Actigraphy

Donyea Moore,
Rachel Nolte,
Yitong Huang,
Shreya Maharana,
Pavan Nataraj,
Bichun Ouyang and
Mahboobeh Mahdavinia

J. Pers. Med.2025, 15(6), 249;https://doi.org/10.3390/jpm15060249

14 June 2025

Background/Objectives: Chronic rhinosinusitis (CRS) is a persistent inflammatory condition of the sinonasal mucosa lasting for at least three months. For patients, CRS-related sleep disturbances can significantly disrupt circadian rhythms, leading to...

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Article

1 Citations

1,084 Views

14 Pages

Associations Between Chemotherapy-Induced Peripheral Neuropathy and Distress in Patients Assigned to Adjuvant Irradiation for Non-Metastatic Breast Cancer

Dirk Rades,
Tobias Bartscht,
Achim Rody and
Martin Ballegaard

J. Pers. Med.2025, 15(6), 248;https://doi.org/10.3390/jpm15060248

13 June 2025

Background/Objectives: Many patients assigned to adjuvant radiotherapy for non-metastatic breast cancer already received taxane-based chemotherapy, which can cause peripheral neuropathy (PNP). This study investigated potential associations between mo...

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Article

709 Views

10 Pages

Assessing the Impact of Simplified Language on a Patient-Facing Pharmacogenetic Report: A User Comprehension Study

Russell Amato,
Nicole M. Del Toro-Pagan,
Harris Nguyen,
Jordan Plummer,
Katie Pizzolato,
David Krause and
Daniel Dowd

J. Pers. Med.2025, 15(6), 247;https://doi.org/10.3390/jpm15060247

12 June 2025

Background: Pharmacogenetics (PGx) is the science of assessing how genetic variation affects drug efficacy, tolerability, and safety. While PGx is an emerging discipline which is becoming standard of care, many providers have misunderstandings about...

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Article

947 Views

12 Pages

Morphology of Macular Neovascularization in Age-Related Macular Degeneration Influences Treatment Requirement and Visual Outcome After 1 Year

Michael Grün,
Kai Rothaus,
Martin Ziegler,
Albrecht Lommatzsch,
Clemens Lange and
Henrik Faatz

J. Pers. Med.2025, 15(6), 246;https://doi.org/10.3390/jpm15060246

11 June 2025

Background/Objectives: To evaluate the potential of Optical Coherence Tomography (OCT) and OCT angiography parameters in predicting treatment requirements and visual outcomes after one year in therapy-naïve eyes with neovascular age-related macu...

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Article

1 Citations

1,251 Views

21 Pages

Clinical Pharmacogenetics: Results After Implementation of Preemptive Tests in Daily Routine

Xando Díaz-Villamarín,
María Martínez-Pérez,
María Teresa Nieto-Sánchez,
Emilio Fernández-Varón,
Alicia Torres-García,
Isabel Blancas,
José Cabeza-Barrera and
Rocío Morón

J. Pers. Med.2025, 15(6), 245;https://doi.org/10.3390/jpm15060245

10 June 2025

Background/Objectives: The clinical implementation of pharmacogenetics (PGx) remains limited, even for well-established drug–gene interactions. In addition to insufficient infrastructure and PGx education among healthcare professionals, there i...

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Systematic Review

1 Citations

1,718 Views

20 Pages

Can Radiomics Predict Pathologic Complete Response After Neoadjuvant Chemoradiotherapy for Rectal Cancer? A Systematic Review and Meta-Analysis of Diagnostic-Accuracy Studies

Fotios Seretis,
Antonia Panagaki,
Stavroula Tzamouri,
Tania Triantafyllou,
Charikleia Triantopoulou and
Dimitrios Theodorou

J. Pers. Med.2025, 15(6), 244;https://doi.org/10.3390/jpm15060244

10 June 2025

Background: The rectal cancer treatment paradigm is rapidly changing with the advent of total neoadjuvant therapy and non-operative management approaches in responders. A good clinical response to neoadjuvant treatment documented by magnetic resonanc...

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Correction

481 Views

2 Pages

Correction: Viglianisi et al. The Emerging Role of Salivary Oxidative Stress Biomarkers as Prognostic Markers of Periodontitis: New Insights for a Personalized Approach in Dentistry. J. Pers. Med. 2023, 13, 166

Gaia Viglianisi,
Gianluca Martino Tartaglia,
Simona Santonocito,
Mariacristina Amato,
Alessandro Polizzi,
Marco Mascitti and
Gaetano Isola

J. Pers. Med.2025, 15(6), 243;https://doi.org/10.3390/jpm15060243

10 June 2025

Following discussions between the Editorial Board and the authors, the original published references no [...]

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Journal of Personalized Medicine, Volume 15, Issue 6

Articles (49)

Guarded Outcomes After Hip Hemiarthroplasty in Patients with Cerebral Palsy: Highlighting a Personalized Medicine Approach to Mitigate the Risk of Complications

Phenotype-Driven Variability in Longitudinal Body Composition Changes After a Very Low-Calorie Ketogenic Intervention: A Machine Learning Cluster Approach

Overcoming Challenges in Learning Prerequisites for Adaptive Functioning: Tele-Rehabilitation for Young Girls with Rett Syndrome

Tailoring Evaluations of Chronic Rhinosinusitis: Understanding Sleep and Its Effect on Memory Through Actigraphy

Associations Between Chemotherapy-Induced Peripheral Neuropathy and Distress in Patients Assigned to Adjuvant Irradiation for Non-Metastatic Breast Cancer

Assessing the Impact of Simplified Language on a Patient-Facing Pharmacogenetic Report: A User Comprehension Study

Morphology of Macular Neovascularization in Age-Related Macular Degeneration Influences Treatment Requirement and Visual Outcome After 1 Year

Clinical Pharmacogenetics: Results After Implementation of Preemptive Tests in Daily Routine

Can Radiomics Predict Pathologic Complete Response After Neoadjuvant Chemoradiotherapy for Rectal Cancer? A Systematic Review and Meta-Analysis of Diagnostic-Accuracy Studies

Correction: Viglianisi et al. The Emerging Role of Salivary Oxidative Stress Biomarkers as Prognostic Markers of Periodontitis: New Insights for a Personalized Approach in Dentistry. J. Pers. Med. 2023, 13, 166