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Diagnostics, Volume 15, Issue 6

2025 March-2 - 144 articles

Cover Story: Chronic kidney disease in diabetes (DKD) affects up to 50% of people with type 2 diabetes (T2D), leading to high morbidity, mortality, and healthcare costs. The standard of care relies on the estimated glomerular filtration rate (eGFR) and urinary albumin/creatinine ratio (uACR), but these measures are highly variable due to factors like diet and exercise, limiting their accuracy. More precise prognostic tools are needed to improve DKD risk assessment in T2D. This study evaluates the biomarker-based PromarkerD test against eGFR and uACR for predicting kidney decline in people with T2D. PromarkerD demonstrated superior predictive accuracy, identifying 84% of cases that were missed by standard tests, with better risk stratification and fewer false positives. View this paper
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Articles (144)

  • Systematic Review
  • Open Access
4 Citations
1,787 Views
15 Pages

Clinicopathological Comparison Between GREB1- and ESR1-Rearranged Uterine Tumors Resembling Ovarian Sex Cord Tumors (UTROSCTs): A Systematic Review

  • Livia Maccio,
  • Damiano Arciuolo,
  • Angela Santoro,
  • Antonio Raffone,
  • Diego Raimondo,
  • Susanna Ronchi,
  • Nicoletta D’Alessandris,
  • Giulia Scaglione,
  • Michele Valente and
  • Antonio Travaglino
  • + 8 authors

Introduction: Among uterine tumors resembling ovarian sex cord tumors (UTROSCTs), it has been suggested that GREB1-rearranged cases are biologically distinct from ESR1-rearranged cases and might be considered as a separate entity. Objectives: The aim...

(This article belongs to the Section Pathology and Molecular Diagnostics)
  • Article
  • Open Access
2 Citations
1,526 Views
19 Pages

Background: Recent studies have analyzed some cytokines in patients with papillary thyroid carcinoma (PTC), but simultaneous analysis of multiple cytokines remains rare. Nonetheless, the simultaneous assessment of multiple cytokines is increasingly r...

(This article belongs to the Section Clinical Laboratory Medicine)
  • Article
  • Open Access
1,315 Views
14 Pages

Improving Diagnostic Performance for Head and Neck Tumors with Simple Diffusion Kurtosis Imaging and Machine Learning Bi-Parameter Analysis

  • Suzuka Yoshida,
  • Masahiro Kuroda,
  • Yoshihide Nakamura,
  • Yuka Fukumura,
  • Yuki Nakamitsu,
  • Wlla E. Al-Hammad,
  • Kazuhiro Kuroda,
  • Yudai Shimizu,
  • Yoshinori Tanabe and
  • Junichi Asaumi
  • + 7 authors

Background/Objectives: Mean kurtosis (MK) values in simple diffusion kurtosis imaging (SDI)—a type of diffusion kurtosis imaging (DKI)—have been reported to be useful in the diagnosis of head and neck malignancies, for which pre-processin...

(This article belongs to the Section Medical Imaging and Theranostics)
  • Article
  • Open Access
22 Citations
3,007 Views
36 Pages

A Novel Diagnostic Framework with an Optimized Ensemble of Vision Transformers and Convolutional Neural Networks for Enhanced Alzheimer’s Disease Detection in Medical Imaging

  • Joy Chakra Bortty,
  • Gouri Shankar Chakraborty,
  • Inshad Rahman Noman,
  • Salil Batra,
  • Joy Das,
  • Kanchon Kumar Bishnu,
  • Md Tanvir Rahman Tarafder and
  • Araf Islam

Background/Objectives: Alzheimer’s disease (AD) is a progressive, neurodegenerative disorder, which causes memory loss and loss of cognitive functioning, along with behavioral changes. Early detection is important to delay disease progression,...

(This article belongs to the Special Issue Artificial Intelligence in Brain Diseases)
  • Article
  • Open Access
2 Citations
2,483 Views
9 Pages

MRI Detection of Unknown Primary Tumours in the Head and Neck: What Is the Expected Normal Asymmetry in the Size of the Palatine Tonsils?

  • Kaijing Mao,
  • Qi Yong H. Ai,
  • Kuo Feng Hung,
  • Irene O. L. Tse,
  • Ho Sang Leung,
  • Yannis Yan Liang,
  • Yu Chen,
  • Lun M. Wong,
  • W. K. Jacky Lam and
  • Ann D. King

Background/Objectives: The detection of unknown primary tumours in the palatine tonsils (PTs) on imaging relies heavily on asymmetry in size between the right and left sides, but the expected normal range in asymmetry is not well documented. This stu...

(This article belongs to the Special Issue Advances in Diagnosis and Treatment in Otolaryngology)
  • Review
  • Open Access
31 Citations
4,759 Views
28 Pages

AI and Smart Devices in Cardio-Oncology: Advancements in Cardiotoxicity Prediction and Cardiovascular Monitoring

  • Luiza Camelia Nechita,
  • Dana Tutunaru,
  • Aurel Nechita,
  • Andreea Elena Voipan,
  • Daniel Voipan,
  • Ancuta Elena Tupu and
  • Carmina Liana Musat

The increasing prevalence of cardiovascular complications in cancer patients due to cardiotoxic treatments has necessitated advanced monitoring and predictive solutions. Cardio-oncology is an evolving interdisciplinary field that addresses these chal...

(This article belongs to the Special Issue AI-Assisted Diagnostics in Telemedicine and Digital Health)
  • Article
  • Open Access
1,352 Views
10 Pages

Do We Need to Add the Type of Treatment Planning System, Dose Calculation Grid Size, and CT Density Curve to Predictive Models?

  • Reza Reiazi,
  • Surendra Prajapati,
  • Leonardo Che Fru,
  • Dongyeon Lee and
  • Mohammad Salehpour

Background: Generalizability and domain dependency are critical challenges in developing predictive models for healthcare, particularly in medical diagnostics and radiation oncology. Predictive models designed to assess tumor recurrence rely on compr...

(This article belongs to the Special Issue Artificial Intelligence in Clinical Decision Support—2nd Edition)
  • Systematic Review
  • Open Access
7 Citations
6,604 Views
22 Pages

What the Radiologist Needs to Know About Sport Hernias: A Systematic Review of the Current Literature

  • Gian Nicola Bisciotti,
  • Andrea Bisciotti,
  • Alessandro Bisciotti and
  • Alessio Auci

Introduction: The sports hernia (SH) is one of the most important causes of groin pain syndrome (GPS). However, despite its importance in GPS etiopathogenesis, SH is one of the least understood and poorly defined clinical conditions in sports medicin...

(This article belongs to the Special Issue Imaging Diagnosis in Abdomen, 2nd Edition)
  • Article
  • Open Access
4 Citations
5,723 Views
13 Pages

Background: Recent studies indicate that the organo-axial subtype of a sigmoid volvulus is more prevalent than the conventional mesentero-axial subtype. Our study aimed to assess the clinical and radiological findings that differentiate between these...

(This article belongs to the Special Issue Diagnostic Imaging in Gastrointestinal and Liver Diseases)
  • Article
  • Open Access
3 Citations
1,652 Views
16 Pages

Machine Learning Based Multi-Parameter Modeling for Prediction of Post-Inflammatory Lung Changes

  • Gerlig Widmann,
  • Anna Katharina Luger,
  • Thomas Sonnweber,
  • Christoph Schwabl,
  • Katharina Cima,
  • Anna Katharina Gerstner,
  • Alex Pizzini,
  • Sabina Sahanic,
  • Anna Boehm and
  • Piotr Tymoszuk
  • + 8 authors

Objectives: Prediction of lung function deficits following pulmonary infection is challenging and suffers from inaccuracy. We sought to develop machine-learning models for prediction of post-inflammatory lung changes based on COVID-19 recovery data....

(This article belongs to the Section Medical Imaging and Theranostics)
  • Article
  • Open Access
1,916 Views
14 Pages

The Zucker Diabetic Fatty Rat as a Model for Vascular Changes in Diabetic Kidney Disease: Characterising Hydronephrosis

  • Amy McDermott,
  • Nathalie Sarup Panduro,
  • Iman Taghavi,
  • Hans Martin Kjer,
  • Stinne Byrholdt Søgaard,
  • Michael Bachmann Nielsen,
  • Jørgen Arendt Jensen and
  • Charlotte Mehlin Sørensen

Background/Objectives: Diabetic kidney disease (DKD) is a significant concern for global healthcare, particularly in individuals with diabetes. The Zucker rat strain is a commonly used model of type 2 diabetes, despite awareness that this animal can...

(This article belongs to the Special Issue Current Issues in Kidney Diseases Diagnosis and Management 2025)
  • Case Report
  • Open Access
2 Citations
3,329 Views
11 Pages

Cladosporium species novum Invasive Pulmonary Infection in a Patient with Post-COVID-19 Syndrome and AIDS

  • Milorad Bijelović,
  • Nikola Gardić,
  • Aleksandra Lovrenski,
  • Danijela Petrović,
  • Gordana Kozoderović,
  • Vesna Lalošević,
  • Vuk Vračar and
  • Dušan Lalošević

Background and Clinical Significance: Since the prevalence of fungal lung infections is increasing, certain agents, such as Cladosporium spp., have emerged as unexpected causes. Cladosporium spp. fungi are ubiquitous in environments such as soil, fru...

(This article belongs to the Section Pathology and Molecular Diagnostics)
  • Interesting Images
  • Open Access
1,320 Views
4 Pages

Orbital Neurolymphomatosis in Patient with CNS Lymphoma

  • Tara Shooshani,
  • Michael Han,
  • Jeremiah P. Tao,
  • Samuel J. Spiegel and
  • Maria Del Valle Estopinal

Neurolymphomatosis (NL) is a rare manifestation of hematologic malignancies, characterized by a neoplastic infiltration of the peripheral nervous system and cranial nerves (CNs). Non-Hodgkin lymphomas (NHLs) account for 90% of NL cases, while acute l...

(This article belongs to the Special Issue Pathology and Diagnosis of Head and Neck Diseases)
  • Article
  • Open Access
2 Citations
2,044 Views
14 Pages

The Association of Heart Failure and Liver T1 Mapping in Cardiac Magnetic Resonance Imaging

  • Adrian T. Huber,
  • Joanna Bartkowiak,
  • Robin Seitz,
  • Benedikt Bernhard,
  • Martina Boscolo Berto,
  • Giancarlo Spano,
  • Benedikt Wagner,
  • Verena C. Obmann,
  • Lukas Ebner and
  • Alan A. Peters
  • + 12 authors

Background/Objectives: The objective of this study was to investigate the association between congestive heart failure (CHF) and T1 mapping in both liver lobes using cardiac MRI. Methods: This retrospective study included patients who underwent cardi...

(This article belongs to the Section Medical Imaging and Theranostics)
  • Review
  • Open Access
2 Citations
5,209 Views
18 Pages

The Role of Autopsy in Diagnosing Fatal Chest Injuries in Road Traffic Accidents: A Literature Review

  • Matteo Antonio Sacco,
  • Maria Cristina Verrina,
  • Saverio Gualtieri,
  • Agostinho Santos,
  • Bárbara Ferreira Mendes,
  • Alessandro Pasquale Tarallo,
  • Aurora Princi,
  • Stefano Lombardo,
  • Pietrantonio Ricci and
  • Isabella Aquila

Road accidents are one of the leading causes of death worldwide, with significant repercussions on public health and the global economy. Fatal accidents can cause injuries in various anatomical areas with different dynamics. The thorax is one of the...

(This article belongs to the Special Issue Advances in Forensic Medical Diagnosis)
  • Article
  • Open Access
3 Citations
1,903 Views
12 Pages

Impact of Radiologist Experience on AI Annotation Quality in Chest Radiographs: A Comparative Analysis

  • Malte Michel Multusch,
  • Lasse Hansen,
  • Mattias Paul Heinrich,
  • Lennart Berkel,
  • Axel Saalbach,
  • Heinrich Schulz,
  • Franz Wegner,
  • Joerg Barkhausen and
  • Malte Maria Sieren

Background/Objectives: In the burgeoning field of medical imaging and Artificial Intelligence (AI), high-quality annotations for training AI-models are crucial. However, there are still only a few large datasets, as segmentation is time-consuming, ex...

(This article belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)
  • Review
  • Open Access
8 Citations
4,046 Views
16 Pages

Deep Learning Models to Detect Anterior Cruciate Ligament Injury on MRI: A Comprehensive Review

  • Michele Mercurio,
  • Federica Denami,
  • Dimitra Melissaridou,
  • Katia Corona,
  • Simone Cerciello,
  • Domenico Laganà,
  • Giorgio Gasparini and
  • Roberto Minici

Magnetic resonance imaging (MRI) is routinely used to confirm the suspected diagnosis of anterior cruciate ligament (ACL) injury. Recently, many studies explored the role of artificial intelligence (AI) and deep learning (DL), a sub-category of AI, i...

(This article belongs to the Special Issue Artificial Intelligence in Clinical Medical Imaging: 2nd Edition)
  • Case Report
  • Open Access
6 Citations
5,021 Views
14 Pages

Background and clinical significance: Large-cell neuroendocrine carcinoma (LCNEC) of the cervix is considered a rare type of cancer: it represents <1% of invasive cervical cancers. The optimal treatment protocol is not fully established because of...

(This article belongs to the Section Clinical Diagnosis and Prognosis)
  • Case Report
  • Open Access
4 Citations
2,881 Views
10 Pages

A Silent Threat: Internal Carotid Artery Hypoplasia and Its Role in Basilar Artery Aneurysm Formation—A Case Study

  • Paula Mežvinska,
  • Artis Brokāns,
  • Sergejs Pavlovičs,
  • Matīss Dravnieks,
  • Ardis Platkājis and
  • Arturs Balodis

Background and Clinical Significance: Hypoplasia of the internal carotid artery (ICA) is a rare vascular anomaly, with an estimated incidence of less than 0.01%. This condition can result in reduced blood flow to the anterior circulation, often compe...

(This article belongs to the Section Medical Imaging and Theranostics)
  • Article
  • Open Access
15 Citations
3,355 Views
20 Pages

Background: Parkinson’s disease (PD) is one of the most prevalent, widespread, and intricate neurodegenerative disorders. According to the experts, at least 1% of people over the age of 60 are affected worldwide. In the present time, the early...

(This article belongs to the Special Issue Artificial Intelligence and Pattern Recognition Methods for the Automatic Detection and Evaluation of Neurological Disorders, 2nd Edition)
  • Article
  • Open Access
1 Citations
3,901 Views
10 Pages

Background/Objectives: This study aimed to provide a descriptive review of fetal aberrant right subclavian artery (ARSA), with a discussion of the genomic and structural anatomy and perinatal prognosis in our hospital’s obstetric department. Me...

(This article belongs to the Special Issue Advancements in Maternal–Fetal Medicine)
  • Article
  • Open Access
2,771 Views
12 Pages

Predictors of Diagnostic Inaccuracy of Detecting Coronary Artery Stenosis by Preprocedural CT Angiography in Patients Prior to Transcatheter Aortic Valve Implantation

  • Matthias Renker,
  • Steffen D. Kriechbaum,
  • Stefan Baumann,
  • Christian Tesche,
  • Grigorios Korosoglou,
  • Efstratios I. Charitos,
  • Birgid Gonska,
  • Tim Seidler,
  • Yeong-Hoon Choi and
  • Samuel T. Sossalla
  • + 2 authors

Background: The diagnostic performance of preprocedural CT angiography in detecting coronary artery disease (CAD) in patients scheduled for transcatheter aortic valve implantation (TAVI) has been reported. However, data on predictors of diagnostic in...

(This article belongs to the Section Medical Imaging and Theranostics)
  • Article
  • Open Access
4 Citations
3,157 Views
10 Pages

Correlation Between Condylar Shape and Malocclusion: CBCT Analysis

  • Neamat Hassan Abubakr,
  • Tanya Al-Talib,
  • Nastaran Bahar,
  • Arshia Badani,
  • Stanely Nelson and
  • Jyoti Mago

Background/Objectives: This study introduces a novel classification system using cone-beam computed tomography (CBCT) to assess condylar morphology and its correlation with different skeletal classifications. Methods: A retrospective CBCT analysis of...

(This article belongs to the Special Issue Advances in Oral and Maxillofacial Radiology)
  • Systematic Review
  • Open Access
12 Citations
3,923 Views
14 Pages

Evidence Report on the Safety of Gastrointestinal Endoscopy in Patients on Glucagon-like Peptide-1 Receptor Agonists: A Systematic Review and Meta-Analysis

  • Zahid Ijaz Tarar,
  • Umer Farooq,
  • Ahtshamullah Chaudhry,
  • Mustafa Gandhi,
  • Abdallah El Alayli,
  • Mark Ayoub,
  • Baltej Singh,
  • Ebubekir Daglilar and
  • Nirav Thosani

Background/Objectives: Glucagon-like peptide-1 receptor agonists are increasingly used worldwide for weight and hyperglycemia management. There is an ongoing debate on the presence of increased gastric residue, leading to complications such as aspira...

(This article belongs to the Special Issue Endoscopy in Diagnosis of Gastrointestinal Disorders—2nd Edition)
  • Article
  • Open Access
5 Citations
4,007 Views
11 Pages

Ultrasound Screening in the First and Second Trimester of Pregnancy for the Detection of Fetal Cardiac Anomalies in a Low-Risk Population

  • Aura Iuliana Popa,
  • Nicolae Cernea,
  • Marius Cristian Marinaș,
  • Maria Cristina Comănescu,
  • Ovidiu Costinel Sîrbu,
  • Dragoș George Popa,
  • Larisa Pătru,
  • Vlad Pădureanu and
  • Ciprian Laurențiu Pătru

Background/Objectives: Congenital heart disease (CHD) is the most common birth defect, an important cause of morbidity and mortality, with a reported prevalence of 5–12 per 1000 live births. The aim of our study was to identify the role of feta...

(This article belongs to the Special Issue Echocardiography Applications in Cardiovascular Diseases)
  • Review
  • Open Access
12 Citations
8,481 Views
17 Pages

Radiological Assessment of Charcot Neuro-Osteoarthropathy in Diabetic Foot: A Narrative Review

  • Antonio Mascio,
  • Chiara Comisi,
  • Virginia Cinelli,
  • Dario Pitocco,
  • Tommaso Greco,
  • Giulio Maccauro and
  • Carlo Perisano

Charcot Neuro-Osteoarthropathy (CNO) is a debilitating complication predominantly affecting individuals with diabetes and peripheral neuropathy. Radiological assessment plays a central role in the diagnosis, staging, and management of CNO. While plai...

(This article belongs to the Special Issue Recent Advances in Bone and Joint Imaging—2nd Edition)
  • Article
  • Open Access
6 Citations
3,654 Views
16 Pages

Contact Allergy in Atopic Dermatitis and Psoriasis: A Retrospective Study

  • Domenico Bonamonte,
  • Aurora De Marco,
  • Giulia Ciccarese,
  • Paolo Romita,
  • Giulio Giancaspro,
  • Francesca Ambrogio and
  • Caterina Foti

Background/Objectives: The correlation between contact allergy (CA), atopic dermatitis (AD) and psoriasis is still debated. Therefore, the present study aims to retrospectively analyze the frequency of contact sensitization among patients with psoria...

(This article belongs to the Section Diagnostic Microbiology and Infectious Disease)
  • Case Report
  • Open Access
3,161 Views
12 Pages

Background and Clinical Significance: Dental implants are widely used; however, tooth extraction often results in alveolar bone loss and gingival recession, necessitating bone and connective tissue reconstruction, especially in the esthetic anterior...

(This article belongs to the Section Medical Imaging and Theranostics)
  • Article
  • Open Access
9 Citations
3,032 Views
14 Pages

Background/Objectives: Learning disabilities (LDs) are complex neurodevelopmental conditions influenced by genetic, epigenetic, and environmental factors. Recent research suggests that maternal autoimmune conditions, perinatal stress, and vitamin D d...

(This article belongs to the Special Issue EEG Analysis in Diagnostics)
  • Article
  • Open Access
1 Citations
3,771 Views
12 Pages

Foveal Hypoplasia Grading with Optical Coherence Tomography: Agreement and Challenges Across Experience Levels

  • Riddhi Shenoy,
  • Gail D. E. Maconachie,
  • Swati Parida,
  • Zhanhan Tu,
  • Abdullah Aamir,
  • Chung S. Chean,
  • Ayesha Roked,
  • Michael Taylor,
  • George Garratt and
  • Mervyn G. Thomas
  • + 12 authors

Background/Objectives: The diagnosis and prognosis of arrested foveal development or foveal hypoplasia (FH) can be made using the Leicester grading system for FH and optical coherence tomography (OCT). In clinical practice, ophthalmologists and ophth...

(This article belongs to the Special Issue New Perspectives in Ophthalmic Imaging)
  • Article
  • Open Access
2 Citations
9,946 Views
15 Pages

Pathogen Detection and Diagnostic Scenarios in Chronic Prostatitis

  • Vittorio Magri,
  • Gianpaolo Perletti and
  • Konstantinos Stamatiou

Background/Objectives: Chronic prostatitis (CP) is characterized by a variety of symptoms, including pelvic pain, urinary disturbances, and sexual dysfunction, often without clear signs of infection, which complicates its diagnosis. For decades, the...

(This article belongs to the Section Diagnostic Microbiology and Infectious Disease)
  • Article
  • Open Access
2 Citations
1,620 Views
21 Pages

Background: Melanoma is a highly aggressive form of skin cancer, necessitating early and accurate detection for effective treatment. This study aims to develop a novel classification system for melanoma detection that integrates Convolutional Neural...

(This article belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)
  • Article
  • Open Access
1,210 Views
14 Pages

The Relationship Between Aortic Stenosis and the Possibility of Subsequent Macular Diseases: A Nationwide Database Study

  • Chia-Yi Lee,
  • Shun-Fa Yang,
  • Elsa Lin-Chin Mai,
  • Jing-Yang Huang,
  • Chao-Bin Yeh and
  • Chao-Kai Chang

Objectives: This study aimed to investigate the possible relationship between aortic stenosis (AS) occupancy and the incidence of subsequent macular diseases. Methods: A retrospective cohort study was conducted using the TriNetX database, and partici...

(This article belongs to the Special Issue Diagnosis and Management of Ophthalmic Disorders)
  • Article
  • Open Access
2 Citations
3,393 Views
14 Pages

Spontaneously Opening and Closing Macular Holes with Lamellar Hole Epiretinal Proliferation: A Longitudinal Optical Coherence Tomography Analysis

  • Omar Moussa,
  • Jedrzej Golebka,
  • Gabriel Gomide,
  • Dvir Koenigstein,
  • Hueyjong Shih and
  • Royce W. S. Chen

Background/Objectives: Spontaneous macular hole closure is a rare phenomenon, with lamellar hole epiretinal proliferation (LHEP) frequently implicated as a potential mechanism. This study aims to analyze the presence of LHEP in patients with full-thi...

(This article belongs to the Special Issue Optical Coherence Tomography in Diagnosis of Ophthalmology Disease)
  • Interesting Images
  • Open Access
1,912 Views
7 Pages

Unilateral Reverse Pupillary Block Associated with Multiple Ciliary Body Cysts and Pseudoexfoliative Syndrome

  • Idoia Goñi Guarro,
  • Mia Zorić Geber,
  • Rašeljka Tadić,
  • Renata Iveković and
  • Zoran Vatavuk

The aim of this study is to present interesting images of a clinical case of asymmetrical bilateral ciliary body cysts associated with pseudoexfoliative syndrome (PEX), leading to unilateral reverse pupillary block and subsequent secondary angle-clos...

(This article belongs to the Special Issue Optical Imaging: Trends, Impact, and Application in Medical and Biomedical Diagnostics)
  • Article
  • Open Access
1 Citations
1,961 Views
9 Pages

The Survival Rate of Living-Donor Liver Transplantation Between Same-Sex and Opposite-Sex Recipients

  • Mei-Yun Wu,
  • Yu-Hung Lin,
  • Wei-Juo Tzeng,
  • Shih-Feng Weng,
  • Wan-Ching Chang and
  • Chich-Hsiu Hung

Purpose: Living-donor liver transplantation (LDLT) serves as a solution for patients facing end-stage liver disease. The existing literature indicates that sex differences between transplant donors and recipients might influence survival rates. Metho...

(This article belongs to the Section Clinical Diagnosis and Prognosis)
  • Article
  • Open Access
4 Citations
2,899 Views
18 Pages

Objective: Electronic health records (EHRs) are becoming increasingly important in both academic research and business applications. Recent studies indicate that predictive tasks, such as heart failure detection, perform better when the geometric str...

  • Review
  • Open Access
12 Citations
11,244 Views
19 Pages

Lung Ultrasound in Critical Care: A Narrative Review

  • Lee Berry,
  • Lucas Rehnberg,
  • Paul Groves,
  • Martin Knight,
  • Michael Stewart and
  • Ahilanandan Dushianthan

Lung ultrasound (LUS) has become a crucial part of the investigative tools available in the management of critically ill patients, both within the intensive care unit setting and in prehospital medicine. The increase in its application, in part drive...

(This article belongs to the Special Issue Advances in the Diagnosis and Management of Respiratory Illnesses)
  • Interesting Images
  • Open Access
1,013 Views
5 Pages

Macular Telangiectasia (MacTel) is a rare retinal vascular disorder, with Type 3a MacTel being a distinct form characterized by retinal ischemia with the classical findings of MacTel, such as juxtafoveal telangiectasis, right-angled venules, and deep...

(This article belongs to the Special Issue Diagnosis and Management of Ophthalmic Disorders)
  • Article
  • Open Access
3 Citations
1,437 Views
12 Pages

Total Intramuscular Fat Fraction of Thigh Muscles as a Predictor of Nusinersen Efficacy in Pediatric SMA Type II and III

  • Kiiko Iketani,
  • Hiroyuki Awano,
  • Hiromi Hashimura,
  • Shoko Sonehara,
  • Hiroaki Hanafusa,
  • Yoshinori Nambu,
  • Hisahide Nishio,
  • Kandai Nozu and
  • Ryosuke Bo

Background/Objectives: Nusinersen is a disease-modifying drug for spinal muscular atrophy (SMA) that improves motor function. However, its effects on the skeletal muscles remain unclear. This study aimed to assess the intramuscular fat fraction in pa...

(This article belongs to the Section Clinical Diagnosis and Prognosis)
  • Article
  • Open Access
4 Citations
1,660 Views
12 Pages

Background: Circulating tumor cells (CTCs) have recently been developed as biomarkers. Several studies have reported on the clinical use of CTCs to assess drug resistance in various cancers. However, sequential and multiple CTC measurements during ch...

(This article belongs to the Special Issue Advances in Cell-Based Technologies for Precision Diagnostics)
  • Review
  • Open Access
3 Citations
5,083 Views
17 Pages

Acute-on-Chronic Liver Failure: Steps Towards Consensus

  • Loredana Gabriela Goran,
  • Florina Alexandra Liţă (Cofaru) and
  • Carmen Fierbinţeanu-Braticevici

Acute-on-chronic liver failure (ACLF) is a clinical syndrome characterized by organ failure and high short-term mortality. Since its first definition in 2013, many international organizations have defined this syndrome and, till now, there has been n...

(This article belongs to the Section Clinical Diagnosis and Prognosis)
  • Article
  • Open Access
1 Citations
2,612 Views
28 Pages

Utility of Weight-Bearing Computed Tomography in the Postoperative Assessment of Ankle Fractures

  • Mateusz Malik,
  • Jakub Kwiatkowski,
  • Artur Gądek,
  • Agnieszka Lechowska-Liszka and
  • Henryk Liszka

Background: Ankle fractures are among the most common injuries requiring surgical intervention. Standard radiographs are typically used for postoperative assessment; however, some patients continue to experience residual symptoms despite satisfactory...

(This article belongs to the Special Issue Advances in Foot and Ankle Surgery: Diagnosis and Management)
  • Article
  • Open Access
2,202 Views
12 Pages

Impact of Pitching on Infraspinatus Muscle Elasticity in High School Baseball Pitchers: A Continuous Shear Wave Elastography Study

  • Hitoshi Shitara,
  • Ren Koda,
  • Tsuyoshi Tajika,
  • Tsuyoshi Sasaki,
  • Masataka Kamiyama,
  • Ryosuke Miyamoto,
  • Yuhei Hatori,
  • Koichiro Yanai,
  • Kurumi Nakase and
  • Hirotaka Chikuda
  • + 3 authors

Background/Objectives: The repetitive overhead throwing of baseball stresses the posterior shoulder, including the rotator cuff and capsule, causing stiffness, tissue thickening, and dysfunction. Previous studies on collegiate baseball players have l...

(This article belongs to the Special Issue Advances in Elastography for Applications in Rehabilitation, Physiotherapy, and Sports Sciences)
  • Article
  • Open Access
15 Citations
3,843 Views
16 Pages

Fractal Dimension Analysis of Mandibular Trabecular Bone in Patients Receiving Antiresorptive Therapy for Osteoporosis and Oncologic Conditions

  • Mehmet Altay Sevimay,
  • Müjde Gürsu,
  • Muhammed Abdullah Çege,
  • Dilek Aynur Çankal,
  • Zühre Akarslan and
  • Sedat Çetiner

Objectives: This study aimed to assess the effects of antiresorptive drugs on mandibular trabecular bone structure in patients with osteoporosis and those receiving antiresorptive therapy for oncologic conditions using fractal dimension (FD) analysis...

(This article belongs to the Special Issue Diagnosis and Management of Dental Medicine and Surgery)
  • Article
  • Open Access
5 Citations
1,229 Views
14 Pages

Scintigraphic Assessment of Pulmonary Flow in Patients After Pneumonectomy

  • Bogumił Maciąg,
  • Małgorzata Edyta Wojtyś,
  • Arkadiusz Waloryszak,
  • Norbert Wójcik,
  • Jarosław Pieróg,
  • Krzysztof Safranow,
  • Tadeusz Sulikowski,
  • Tomasz Grodzki and
  • Janusz Wójcik

Background: Pulmonary circulation typically shows flow divided between the right and left lungs, with a marked predominance of the right lung. Pneumonectomy reduces pulmonary circulation by ~50%, irreversibly changing the pulmonary perfusion characte...

(This article belongs to the Special Issue New Advances in Thoracic Surgery: Clinical Diagnosis, Treatment, and Prognosis)
  • Article
  • Open Access
7 Citations
2,401 Views
12 Pages

Evaluation of Hologic LOCalizer™ RFID Tags for Preoperative Localization of Breast Lesions: A Single-Center Experience

  • Charlotte Munday,
  • Anmol Malhotra,
  • Sawsan Taif,
  • Adeola Omotade,
  • Arathi Menon and
  • Kefah Mokbel

Background: The increasing detection of non-palpable breast lesions necessitates accurate preoperative localization to ensure complete excision while preserving healthy tissue and optimizing cosmetic outcomes. Traditional wire-guided localization (WL...

(This article belongs to the Section Medical Imaging and Theranostics)
  • Correction
  • Open Access
713 Views
2 Pages

Correction: del Re et al. Data from Emergency Medical Service Activities: A Novel Approach to Monitoring COVID-19 and Other Infectious Diseases. Diagnostics 2025, 15, 181

  • Daniele del Re,
  • Luigi Palla,
  • Paolo Meridiani,
  • Livia Soffi,
  • Michele Tancredi Loiudice,
  • Martina Antinozzi and
  • Maria Sofia Cattaruzza

In the original publication [...]

(This article belongs to the Special Issue Advances in Disease Prediction)
  • Article
  • Open Access
6 Citations
6,768 Views
13 Pages

An Instant Relationship Between Hyponatremia, Geriatric Syndromes, and Drugs in Older Adults: A Cross-Sectional Analysis from a Single Geriatric Clinic

  • Ali Ekrem Aydin,
  • Esra Ates Bulut,
  • Suleyman Emre Kocyigit,
  • Fatma Sena Dost,
  • Feyza Mutlay,
  • Kubra Altunkalem Seydi,
  • Fethiye Esenkaya and
  • Ahmet Turan Isik

Background: Hyponatremia is a common electrolyte disorder in older adults that can lead to poor clinical outcomes and increased mortality. This study aims to evaluate the interrelationship between hyponatremia and geriatric syndromes and drugs in old...

(This article belongs to the Section Clinical Laboratory Medicine)
  • Systematic Review
  • Open Access
7 Citations
6,833 Views
20 Pages

A Systematic Review: State of the Science on Diagnostics of Hidden Hearing Loss

  • Sunil Shenoy,
  • Khushi Bhatt,
  • Yalda Yazdani,
  • Helia Rahimian,
  • Hamid R. Djalilian and
  • Mehdi Abouzari

Background/Objectives: A sizeable population of patients with normal pure-tone audiograms endorse a consistent difficulty of following conversations in noisy environments. Termed hidden hearing loss (HHL), this condition evades traditional diagnostic...

(This article belongs to the Special Issue Pathology and Diagnosis of Head and Neck Diseases)

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Diagnostics - ISSN 2075-4418