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Diagnostics, Volume 15, Issue 13

2025 July-1 - 159 articles

Cover Story: Peripheral nerve injuries represent a significant challenge in legal medicine, and their proper management and evaluation are at the intersection of clinical medicine, anatomical science, and legal medicine. In this review, we aimed to integrate current knowledge about the anatomy, physiology, clinical management, and paraclinical assessment of peripheral nerve injuries, targeted explicitly for medical–legal practice. We conducted a comprehensive review of the medical–legal evaluation framework needed to evaluate peripheral nerve injuries, with particular emphasis on anatomical variations, imaging techniques, and methods to assess the timing of injury. View this paper
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Articles (159)

  • Article
  • Open Access
1 Citations
2,278 Views
17 Pages

RADAI: A Deep Learning-Based Classification of Lung Abnormalities in Chest X-Rays

  • Hanan Aljuaid,
  • Hessa Albalahad,
  • Walaa Alshuaibi,
  • Shahad Almutairi,
  • Tahani Hamad Aljohani,
  • Nazar Hussain and
  • Farah Mohammad

Background: Chest X-rays are rapidly gaining prominence as a prevalent diagnostic tool, as recognized by the World Health Organization (WHO). However, interpreting chest X-rays can be demanding and time-consuming, even for experienced radiologists, l...

  • Article
  • Open Access
1,391 Views
13 Pages

Bisphosphonate Use and Cardiovascular Outcomes According to Kidney Function Status in Post-Menopausal Women: An Emulated Target Trial from the Multi-Ethnic Study of Atherosclerosis

  • Elena Ghotbi,
  • Nikhil Subhas,
  • Michael P. Bancks,
  • Sammy Elmariah,
  • Jonathan L. Halperin,
  • David A. Bluemke,
  • Bryan R Kestenbaum,
  • R. Graham Barr,
  • Wendy S. Post and
  • Shadpour Demehri
  • + 2 authors

Background/Objectives: Bisphosphonates may influence vascular calcification and atheroma formation via farnesyl pyrophosphate synthase inhibition in the mevalonate pathway regulating bone and lipid metabolism. However, the clinical impact of NCB use...

  • Review
  • Open Access
1,314 Views
9 Pages

Pressure Gradient-Driven Embolization b-TACE for HCC: Technical and Diagnostic Step-by-Step Procedural Guide and Literature Review

  • Bianca Rocco,
  • David C. Madoff,
  • Fabrizio Basilico,
  • Elio Damato,
  • Paolo Vetri,
  • Valeria Panebianco,
  • Carlo Catalano and
  • Pierleone Lucatelli

Background: Hepatocellular carcinoma (HCC) is one of the leading cause of cancer death worldwide. Transarterial therapies represent an important tool in the management of different clinical scenarios, from a patient with a single nodule to a patient...

  • Article
  • Open Access
1,402 Views
10 Pages

The Effect of Intrauterine Device Use on the Quality of Sampling Material in Patients Undergoing Endometrial Biopsy

  • Hüseyin Aksoy,
  • Mehmet Çopuroğlu,
  • Mehmet Genco,
  • Merve Genco and
  • Mürüvet Korkmaz Baştürk

Objective: This retrospective study aims to evaluate the effect of copper intrauterine device (Cu-IUD) use on the adequacy and diagnostic quality of endometrial biopsy specimens in women with abnormal uterine bleeding (AUB). Patients with levonorgest...

  • Article
  • Open Access
2 Citations
3,276 Views
18 Pages

Changing Etiological Spectrum of Premature Ovarian Insufficiency over the Past Decades: A Comparative Analysis of Two Cohorts from a Single Center

  • Szilvia Csehely,
  • Adrienn Kun,
  • Edina Orbán,
  • Tamás Katona,
  • Mónika Orosz,
  • Zoárd Tibor Krasznai,
  • Tamás Deli and
  • Attila Jakab

Background: Premature ovarian insufficiency (POI) is a complex and heterogeneous condition affecting women of reproductive age. Historically, most POI cases have been classified as idiopathic due to limited diagnostic capabilities. However, due to th...

  • Article
  • Open Access
1,049 Views
16 Pages

Perioperative Risk Prediction in Major Gynaecological Oncology Surgery: A National Diagnostic Survey of UK Clinical Practice

  • Lusine Sevinyan,
  • Anil Tailor,
  • Pradeep Prabhu,
  • Peter Williams,
  • Melanie Flint and
  • Thumuluru Kavitha Madhuri

Background: Gynaecological oncology (GO) surgery involves a wide range of procedures, from minor diagnostic interventions to highly complex cytoreductive operations. Accurate perioperative diagnostics—particularly in major surgery—are cri...

  • Case Report
  • Open Access
1,148 Views
15 Pages

Two Cases of Chronic Tubular Necrosis Presenting as Fanconi Syndrome Induced by Red Yeast Rice Choleste-Help

  • Kanako Mita,
  • Shunsuke Takahashi,
  • Satoshi Yanagida,
  • Akihiro Aoyama,
  • Takayuki Shiraishi,
  • Takayuki Hamada,
  • Yumiko Nakamura,
  • Mariko Sato,
  • Kento Hirose and
  • Akito Maeshima
  • + 6 authors

Background and Clinical Significance: Although dietary supplements have often been deemed safe, some have been linked to drug-induced nephropathy due to their diverse ingredients. The aim of this report is to enhance clinical awareness of a novel and...

  • Article
  • Open Access
1 Citations
896 Views
12 Pages

Background/Objectives: A thorough understanding of tooth anatomy is essential for effective root canal treatment. This study aims to investigate the root canal morphology of mandibular incisors (MIs) and the presence of distolingual roots in mandibul...

  • Article
  • Open Access
1,582 Views
10 Pages

Assessing the Reliability of D-Dimer Measurement in EDTA Plasma: A Comparison to the Established Citrate Method

  • Daniel Pfingst,
  • Adriana Méndez,
  • Peter Neyer,
  • Henning Nilius,
  • Nicole Schaub,
  • Patricia Keusch,
  • Michael Nagler and
  • Angelika Hammerer-Lercher

Background: D-dimer determined in citrated plasma is a well-established and efficient biomarker, particularly for ruling out venous thromboembolism. In certain clinical settings, the availability of citrated plasma may pose challenges when not readil...

  • Article
  • Open Access
1,080 Views
16 Pages

Variability of Metabolic Rate and Distribution Volume Quantification in Whole-Body Parametric PATLAK [18F]-FDG PET/CT—A Prospective Trial in Patients with Lung Cancer

  • Stephan Ursprung,
  • Lars Zender,
  • Patrick Ghibes,
  • Florian Hagen,
  • Konstantin Nikolaou,
  • Christian la Fougère and
  • Matthias Weissinger

Background: The recent introduction of whole-body positron emission tomography/ computed tomography (PET/CT) scanners and multi-bed, multi-time point acquisition technique enable calculating fluorodeoxyglucose (FDG) kinetics in the whole body. Howeve...

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Diagnostics - ISSN 2075-4418