Challenges and Innovations in Biomaterials for Tissue Engineering

A special issue of Life (ISSN 2075-1729). This special issue belongs to the section "Cell Biology and Tissue Engineering".

Deadline for manuscript submissions: 20 August 2026 | Viewed by 6

Special Issue Editors

College of Natural Science, Michigan State University, 426 Chemistry Building, East Lansing, MI 48824, USA
Interests: glycoscience; biomaterials; nanoparticles; hydrogels; immunotherapy

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Guest Editor
College of Engineering, University of Notre Dame, Notre Dame, IN, USA
Interests: material

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Guest Editor
Department of Biology, University of Dayton, Dayton, OH, USA
Interests: breast cancer; glioblastoma

Special Issue Information

Dear Colleagues,

Recent advances in biomaterials have greatly expanded the frontiers of tissue engineering and regenerative medicine. Yet, many challenges remain in designing materials that can truly recapitulate the complexity of native tissues, dynamically interact with cells, and promote functional regeneration. This Special Issue aims to highlight the latest progress, emerging concepts, and persistent barriers in the development and application of biomaterials for tissue repair and regeneration.

We invite original research articles, reviews, and perspectives that explore innovative materials design, fabrication strategies, and bioengineering approaches to address unmet clinical needs. Topics of interest include, but are not limited to, smart and bio-responsive materials, hydrogel and nanoparticle systems for controlled delivery, extracellular matrix–mimicking scaffolds, microfluidic and 3D bioprinting platforms, and translational studies bridging laboratory findings to clinical applications.

By bringing together contributions from multidisciplinary fields—including materials chemistry, biology, and engineering—this Special Issue seeks to foster a deeper understanding of the interplay between biomaterials and biological systems. Through this collection, we aim to identify key challenges, inspire new directions, and accelerate innovations that will shape the next generation of tissue engineering strategies.

Researchers working on the design, engineering, characterization, and application of advanced biomaterials are warmly encouraged to contribute their latest findings to this Special Issue.

Dr. Fei Fan
Dr. Donny Hanjaya-Putra
Dr. Loan Bui
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Life is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • hydrogels
  • nanoparticles
  • extracellular matrix
  • microfluidics
  • bio-responsive
  • tissue engineering
  • regenerative medicine

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Published Papers

This special issue is now open for submission.
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