New Insights into Parkinson’s Disease: From Molecular Basis to Therapy
A special issue of Life (ISSN 2075-1729). This special issue belongs to the section "Medical Research".
Deadline for manuscript submissions: 30 November 2025 | Viewed by 2300
Special Issue Editor
Interests: genetics; neurodegeneration; Parkinson’s disease; Alzheimer’s disease; biomarkers; pharmacogenetics
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Parkinson’s disease (PD) is the second most common neurodegenerative disease affecting 1–2% of the population over the age of 65 years. About 90–95% of PD patients have sporadic disease attributed to interactions between environmental and genetic factors, whereas approximately 5–10% of PD cases are familial, following an autosomal dominant or autosomal recessive mode of inheritance. Advances in the field of genetics have aided the identification of specific genes and the recognition of molecular pathways relevant to PD pathogenesis.
In this Special Issue entitled “New Insights into Parkinson’s Disease: From Molecular Basis to Therapy”, submissions are invited (research articles, reviews, meta-analyses, case reports, etc.) that enhance our knowledge of the genetic background of PD, aiming to better delineate genetic and epigenetic contributions to disease progression, increase our understanding on the exact pathophysiologic mechanisms implicated in PD, utilize genetic information to facilitate the diagnosis and prediction of this disease, as well as enable more tailored and effective therapeutic approaches for patients experiencing this neurodegenerative disease.
Dr. Kallirhoe Kalinderi
Guest Editor
Manuscript Submission Information
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Keywords
- Parkinson’s disease
- neurodegeneration
- genes
- GWAs
- polygenic risk score
- therapy
- precision medicine
- pathways
- pharmacogenetics
- surgicogenomics
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