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New Insights into Parkinson’s Disease: From Molecular Basis to Therapy

This special issue belongs to the section “Medical Research“.

Special Issue Information

Dear Colleagues,

Parkinson’s disease (PD) is the second most common neurodegenerative disease affecting 1–2% of the population over the age of 65 years. About 90–95% of PD patients have sporadic disease attributed to interactions between environmental and genetic factors, whereas approximately 5–10% of PD cases are familial, following an autosomal dominant or autosomal recessive mode of inheritance. Advances in the field of genetics have aided the identification of specific genes and the recognition of molecular pathways relevant to PD pathogenesis.

In this Special Issue entitled “New Insights into Parkinson’s Disease: From Molecular Basis to Therapy”, submissions are invited (research articles, reviews, meta-analyses, case reports, etc.) that enhance our knowledge of the genetic background of PD, aiming to better delineate genetic and epigenetic contributions to disease progression, increase our understanding on the exact pathophysiologic mechanisms implicated in PD, utilize genetic information to facilitate the diagnosis and prediction of this disease, as well as enable more tailored and effective therapeutic approaches for patients experiencing this neurodegenerative disease.

Dr. Kallirhoe Kalinderi
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Life is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • Parkinson’s disease
  • neurodegeneration
  • genes
  • GWAs
  • polygenic risk score
  • therapy
  • precision medicine
  • pathways
  • pharmacogenetics
  • surgicogenomics

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Life - ISSN 2075-1729