Advances in Skin-Related Disease: Pathogenesis and Novel Therapeutic Strategies

A special issue of Life (ISSN 2075-1729).

Deadline for manuscript submissions: 31 May 2026 | Viewed by 11

Special Issue Editors


E-Mail Website1 Website2
Guest Editor
Department of Surgical, Medical, Dental and Morphological Sciences, University of Modena and Reggio Emilia, 41124 Modena, Italy
Interests: skin cancer; squamous cell carcinoma; psoriasis; epidermal homeostasis; keratinocyte stem cells; epidermal differentiation; skin inflammation; mouse models; zebrafish models; skin in vitro 3D models; skin tumor spheroids; next-generation sequencing
Special Issues, Collections and Topics in MDPI journals
Department of Surgical, Medical, Dental and Morphological Sciences, University of Modena and Reggio Emilia, 41124 Modena, Italy
Interests: skin cancer; melanoma; squamo cell carcinoma; skin; atopic dermatitis; psoriasis; 3D models; spheroids; skin reconstructs

Special Issue Information

Dear Colleagues,

Skin-related diseases, from common issues such as eczema or acne to more severe conditions such as skin cancer or psoriasis, pose significant challenges for both patients and healthcare providers. Recent advancements in understanding the pathogenesis of these diseases have resulted in groundbreaking insights into their underlying molecular mechanisms. These discoveries are paving the way for innovative therapeutic approaches and more effective treatment.

The pathogenesis of skin diseases involves complex interactions between genetic factors, immune responses, environmental influences, and microbial communities. Researchers are increasingly focusing on inflammation, immune system dysfunction, and alterations in skin barrier function as key contributors to disease development. The skin microbiome is also emerging as a critical player in maintaining skin health and modulating disease processes.

In response to these insights, new therapeutic strategies are being developed. Targeted biologics, small molecules, and gene therapies are revolutionizing treatment options, offering more personalized approaches for patients. Moreover, advances in topical treatments, gene-editing technologies, and microbiome-based therapies have the potential to transform skin disease management in the near future.

For the present Special Issue, we invite researchers in both basic science and clinical/translational research to submit their manuscripts related to the topics described above.

Dr. Elisabetta Palazzo
Dr. Marika Quadri
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Life is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • skin pathologies
  • skin cancer
  • eczema
  • acne
  • psoriasis
  • skin microbiome

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Published Papers

This special issue is now open for submission.
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