Symmetry, Volume 14, Issue 3
2022 March - 202 articles
Cover Story: Symmetry is an intrinsic property of homo-oligomers. In this study, we analyzed the conformational dynamics and flexibility of two amine oxidases, from lentil seedlings (LSAO) and from Euphorbia characias latex (ELAO). Fluorescence spectroscopic data and molecular dynamics demonstrate that slight but significant differences exist at the level of the local tridimensional structure, arising from the presence of large internal cavities, characterized by a different hydration extent. These findings at the light of the topological analysis of the two protein structures demonstrate how the presence of water enhances the degree of connectivity among residues populating the subunits’ interface, which appears mostly asymmetric. View this paper - Issues are regarded as officially published after their release is announced to the table of contents alert mailing list .
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