Polymers, Volume 16, Issue 18
2024 September-2 - 133 articles
Cover Story: This study uncovers the origins of the association between Lysozyme and PAA in water using molecular dynamics simulations and experiments. Simulations reveal that the structure of Lysozyme remains largely stable, with minor conformational changes induced by the PAA and temperature. Thermal treatment affects the complexation process, leading to structural and energy changes, particularly in the α-helices. Amino acid interactions with PAA vary with temperature, influencing the complexation pathway. Electrostatic interactions are dominant in the complex. This information can aid in designing biopolymer/protein materials and understanding protein function under the immobilization of polyelectrolytes and mild denaturation processes. View this paper - Issues are regarded as officially published after their release is announced to the table of contents alert mailing list .
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