Table of Contents
Cancers, Volume 11, Issue 8 (August 2019) – 175 articles
- Issues are regarded as officially published after their release is announced to the table of contents alert mailing list.
- You may sign up for e-mail alerts to receive table of contents of newly released issues.
- PDF is the official format for papers published in both, html and pdf forms. To view the papers in pdf format, click on the "PDF Full-text" link, and use the free Adobe Reader to open them.
Cover Story (view full-size image) Cancer cells have a fundamentally different metabolism than noncancerous cells, and this difference [...] Read more. Cancer cells have a fundamentally different metabolism than noncancerous cells, and this difference is manifested in the endogenous metabolites they produce. Metabolomics aims to study metabolic differences in biological systems and has recently been applied to the discovery of tumor biomarkers in solid tumors. Previous studies reported the utility of the enzyme SSAT-1 as a cancer detection tool. SSAT-1 is a key protein involved in the synthesis of the polyamines spermine and spermidine that are involved in physiological cellular processes. This study led by Singhal and Rolfo et al. evaluated a panel of 14 metabolites associated in the SSAT-1/polyamine pathway that correctly discriminated between lung cancer patients from healthy controls, demonstrating the utility of metabolomics for lung cancer detection and adding further evidence on the role of liquid biopsy in cancer interception. View this paper