Prostate Cancer: Past, Present, and Future

Dear Colleagues,

This Special Issue of the Cancers (2017 Impact Factor: 5.326) will cover all aspects of prostate cancer, which is the most common non-cutaneous malignancy among men, with nearly 1.3 million new cases diagnosed globally in 2018. The highest rates of prostate cancer are noticed in developed countries, and age-adjusted incident rates have increased in recent times due to increased awareness and the availability of prostate-specific antigen (PSA) screening tests. While the use of PSA as a screening biomarker is debatable, prostate cancer undoubtedly is an important health issue that places a significant economic burden on the society. More notably, prostate cancer disproportionately affects men of certain racial/ethnic groups, especially those belonging to a lower socioeconomic status. The highest incidence and mortality rates of prostate cancer are observed among men of African origin, followed by non-Hispanic whites, Hispanics, and Asians/Pacific Islanders. Years of research has tremendously improved prostate cancer management and continues to improve our understanding of the causes and mechanisms of prostate cancer initiation, progression, therapy resistance, and associated health disparities. Evidence continues to grow suggesting genetic and phenotypic diversity of prostate cancer. Resulting insights have emphasized the development of newer screening and diagnostic assays that can not only discriminate between benign and cancerous diseases but are also able to classify them into indolent and potentially aggressive types. New advanced treatment approaches and therapeutic modalities for prostate cancer have also been developed, while several others are being currently evaluated in preclinical or clinical trials. Although the progress thus far in prostate cancer biology and clinical management has been impressive, many gaps in our knowledge still remain. This Special Issue intends to publish emerging data, expert opinions, and reviews to add to the growing knowledge base, and to derive meaningful interpretations from available research and clinical insights in scientific literature.

A broad range of studies on prostate cancer (research, clinical, outreach, and public health) will be considered for inclusion in this Special Issue. We encourage you to submit original, empirical studies as well as systematic reviews or meta-analyses. Short reports and methodological papers will also be considered. Especially, we encourage the submission of interdisciplinary work and multi-country collaborative research.

Prof. Ajay Pratap Singh
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cancers is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.