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Viruses, Volume 11, Issue 7

July 2019 - 97 articles

Cover Story: Sin Nombre (SNV) and Andes (ANDV) viruses cause severe hantavirus cardiopulmonary syndrome (HCPS), which has a lethality rate as high as 35% and no currently available approved therapeutics or vaccines. Here, we show that recombinant VSV expressing SNV or ANDV glycoproteins protects Syrian hamsters against challenges with both forms of hantavirus, providing evidence that a single vaccine could be effective against multiple HCPS-causing agents. View this paper.
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Articles (97)

  • Review
  • Open Access
76 Citations
8,135 Views
17 Pages

A New Era for Mild Strain Cross-Protection

  • Katrin Pechinger,
  • Kar Mun Chooi,
  • Robin M. MacDiarmid,
  • Scott J. Harper and
  • Heiko Ziebell

23 July 2019

Societal and environmental pressures demand high-quality and resilient cropping plants and plant-based foods grown with the use of low or no synthetic chemical inputs. Mild strain cross-protection (MSCP), the pre-immunization of a plant using a mild...

  • Article
  • Open Access
8 Citations
5,043 Views
14 Pages

The Ecology and Phylogeny of Hosts Drive the Enzootic Infection Cycles of Hantaviruses

  • Matthew T. Milholland,
  • Iván Castro-Arellano,
  • Gabriel E. Garcia-Peña and
  • James N. Mills

23 July 2019

Hantaviruses (Family: Hantaviridae; genus: Orthohantavirus) and their associated human diseases occur globally and differ according to their geographic distribution. The structure of small mammal assemblages and phylogenetic relatedness among host sp...

  • Review
  • Open Access
36 Citations
6,606 Views
13 Pages

Bluetongue Virus in France: An Illustration of the European and Mediterranean Context since the 2000s

  • Cindy Kundlacz,
  • Grégory Caignard,
  • Corinne Sailleau,
  • Cyril Viarouge,
  • Lydie Postic,
  • Damien Vitour,
  • Stéphan Zientara and
  • Emmanuel Breard

23 July 2019

Bluetongue (BT) is a non-contagious animal disease transmitted by midges of the Culicoides genus. The etiological agent is the BT virus (BTV) that induces a variety of clinical signs in wild or domestic ruminants. BT is included in the notifiable dis...

  • Review
  • Open Access
59 Citations
10,486 Views
32 Pages

23 July 2019

Viruses are obligate parasites which cause a range of severe plant diseases that affect farm productivity around the world, resulting in immense annual losses of yield. Therefore, control of viral pathogens continues to be an agronomic and scientific...

  • Article
  • Open Access
84 Citations
10,428 Views
25 Pages

Evidence for West Nile Virus and Usutu Virus Infections in Wild and Resident Birds in Germany, 2017 and 2018

  • Friederike Michel,
  • Michael Sieg,
  • Dominik Fischer,
  • Markus Keller,
  • Martin Eiden,
  • Maximilian Reuschel,
  • Volker Schmidt,
  • Rebekka Schwehn,
  • Monika Rinder and
  • Sylvia Urbaniak
  • + 10 authors

23 July 2019

Wild birds play an important role as reservoir hosts and vectors for zoonotic arboviruses and foster their spread. Usutu virus (USUV) has been circulating endemically in Germany since 2011, while West Nile virus (WNV) was first diagnosed in several b...

  • Article
  • Open Access
2 Citations
4,192 Views
13 Pages

Δccr5 Genotype Is Associated with Mild Form of Nephropathia Epidemica

  • Konstantin Kletenkov,
  • Ekaterina Martynova,
  • Yuriy Davidyuk,
  • Emmanuel Kabwe,
  • Anton Shamsutdinov,
  • Ekaterina Garanina,
  • Venera Shakirova,
  • Ilsiyar Khaertynova,
  • Vladimir Anokhin and
  • Rachael Tarlinton
  • + 3 authors

23 July 2019

Nephropathia Epidemica (NE), a mild form of hemorrhagic fever with renal syndrome (HFRS) and linked to hantavirus infection, is endemic in the Republic of Tatarstan. Several genetic markers of HFRS severity have been identified previously, including...

  • Review
  • Open Access
109 Citations
10,199 Views
17 Pages

Exploring the Reservoir Hosts of Tick-Borne Encephalitis Virus

  • Anna Michelitsch,
  • Kerstin Wernike,
  • Christine Klaus,
  • Gerhard Dobler and
  • Martin Beer

22 July 2019

Tick-borne encephalitis virus (TBEV) is an important arbovirus, which is found across large parts of Eurasia and is considered to be a major health risk for humans. Like any other arbovirus, TBEV relies on complex interactions between vectors, reserv...

  • Article
  • Open Access
9 Citations
5,013 Views
12 Pages

Generation of a Reassortant Influenza A Subtype H3N2 Virus Expressing Gaussia Luciferase

  • Lin Wang,
  • Qinghua Cui,
  • Xiujuan Zhao,
  • Ping Li,
  • Yanyan Wang,
  • Lijun Rong and
  • Ruikun Du

20 July 2019

Reporter influenza A viruses (IAVs) carrying fluorescent or luminescent genes provide a powerful tool for both basic and translational research. Most reporter IAVs are based on the backbone of either subtype H1N1 viruses, A/Puerto Rico/8/1934 (PR8) o...

  • Article
  • Open Access
12 Citations
6,181 Views
12 Pages

Reverse Genetics of RNA Viruses: ISA-Based Approach to Control Viral Population Diversity without Modifying Virus Phenotype

  • Jean-Sélim Driouich,
  • Gregory Moureau,
  • Xavier de Lamballerie and
  • Antoine Nougairède

20 July 2019

Reverse genetic systems are essential for the study of RNA viruses. Infectious clones remain the most widely used systems to manipulate viral genomes. Recently, a new PCR-based method called ISA (infectious subgenomic amplicons) has been developed. T...

  • Article
  • Open Access
31 Citations
10,123 Views
10 Pages

A Protocol for Extraction of Infective Viromes Suitable for Metagenomics Sequencing from Low Volume Fecal Samples

  • Ling Deng,
  • Ronalds Silins,
  • Josué L. Castro-Mejía,
  • Witold Kot,
  • Leon Jessen,
  • Jonathan Thorsen,
  • Shiraz Shah,
  • Jakob Stokholm,
  • Hans Bisgaard and
  • Sylvain Moineau
  • + 1 author

20 July 2019

The human gut microbiome (GM) plays an important role in human health and diseases. However, while substantial progress has been made in understanding the role of bacterial inhabitants of the gut, much less is known regarding the viral component of t...

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Viruses - ISSN 1999-4915Creative Common CC BY license