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Viruses, Volume 11, Issue 8

August 2019 - 91 articles

Cover Story: Porcine epidemic diarrhea virus (PEDV) is an enteric coronavirus causing high morbidity and mortality in porcine herds worldwide. The emergence of highly virulent strains and the recurrent outbreaks even in vaccinated farms highlight the need for effective vaccines. We engineered an attenuated live vaccine candidate based on the transmissible gastroenteritis virus (TGEV) genome, expressing a chimeric spike protein from a virulent PEDV strain. This virus conferred protection against a virulent PEDV strain. View this paper.
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Articles (91)

  • Article
  • Open Access
23 Citations
6,647 Views
21 Pages

Molecular Epidemiology of Dengue in Panama: 25 Years of Circulation

  • Yamilka Díaz,
  • María Chen-Germán,
  • Evelia Quiroz,
  • Jean-Paul Carrera,
  • Julio Cisneros,
  • Brechla Moreno,
  • Lizbeth Cerezo,
  • Alex O. Martinez-Torres,
  • Lourdes Moreno and
  • Itza Barahona de Mosca
  • + 4 authors

20 August 2019

Dengue virus (DENV) is the most prevalent arbovirus in terms of human public health importance globally. In addition to DENV epidemiological surveillance, genomic surveillance may help investigators understand the epidemiological dynamics, geographic...

  • Communication
  • Open Access
8 Citations
4,485 Views
10 Pages

Measles Elimination: Identifying Susceptible Sub-Populations to Tailor Immunization Strategies

  • Peter Kreidl,
  • David Ammerer,
  • Reinhard Würzner,
  • Anita Luckner Hornischer,
  • Dorothee von Laer and
  • Wegene Borena

20 August 2019

Measles elimination has been identified as a public health priority in Europe for a long time but has not yet been achieved. The World Health Organization (WHO) recommends identification of susceptible sub-populations to target supplementary immuniza...

  • Article
  • Open Access
6 Citations
4,975 Views
12 Pages

Inhibition of Influenza A Virus by Human Infant Saliva

  • Brad Gilbertson,
  • Kathryn Edenborough,
  • Jodie McVernon and
  • Lorena E. Brown

20 August 2019

Innate antiviral factors in saliva play a role in protection against respiratory infections. We tested the anti-influenza virus activities of saliva samples taken from human infants, 1–12 months old, with no history of prior exposure to influen...

  • Article
  • Open Access
19 Citations
6,496 Views
13 Pages

Specificity of Morbillivirus Hemagglutinins to Recognize SLAM of Different Species

  • Hideo Fukuhara,
  • Yuri Ito,
  • Miyuki Sako,
  • Mizuho Kajikawa,
  • Koki Yoshida,
  • Fumio Seki,
  • Mwila Hilton Mwaba,
  • Takao Hashiguchi,
  • Masa-aki Higashibata and
  • Toyoyuki Ose
  • + 3 authors

19 August 2019

Measles virus (MV) and canine distemper virus (CDV) are highly contagious and deadly, forming part of the morbillivirus genus. The receptor recognition by morbillivirus hemagglutinin (H) is important for determining tissue tropism and host range. Rec...

  • Review
  • Open Access
435 Citations
29,097 Views
18 Pages

Viruses and Autoimmunity: A Review on the Potential Interaction and Molecular Mechanisms

  • Maria K. Smatti,
  • Farhan S. Cyprian,
  • Gheyath K. Nasrallah,
  • Asmaa A. Al Thani,
  • Ruba O. Almishal and
  • Hadi M. Yassine

19 August 2019

For a long time, viruses have been shown to modify the clinical picture of several autoimmune diseases, including type 1 diabetes (T1D), systemic lupus erythematosus (SLE), rheumatoid arthritis (RA), Sjögren’s syndrome (SS), herpetic strom...

  • Article
  • Open Access
2 Citations
4,181 Views
14 Pages

Aichi Virus Induces Antiviral Host Defense in Primary Murine Intestinal Epithelial Cells

  • Yun-Te Chang,
  • Ming-Hsiang Kung,
  • Thung-Hsien Hsu,
  • Wan-Ting Hung,
  • Yao-Shen Chen,
  • Li-Chen Yen and
  • Tsung-Hsien Chang

19 August 2019

The picornavirus Aichi virus (AiV) is a non-enveloped RNA virus that causes acute gastroenteritis symptoms, such as diarrhea, abdominal pain, nausea, vomiting, and fever. Antiviral host defense involves the fast response of type I interferon (IFN) an...

  • Review
  • Open Access
17 Citations
7,181 Views
9 Pages

17 August 2019

Over the past two decades, there has been tremendous progress in understanding the impact of the intestinal microbiota on mammalian metabolism, physiology, and immune development and function. There has also been substantial advancement in elucidatin...

  • Article
  • Open Access
10 Citations
4,367 Views
18 Pages

16 August 2019

Murid herpesvirus-4 (MuHV-4), a natural gammaherpesvirus of rodents, can infect the mouse through the nasal mucosa, where it targets sustentacular cells and olfactory neurons in the olfactory epithelium before it propagates to myeloid cells and then...

  • Review
  • Open Access
33 Citations
10,335 Views
25 Pages

16 August 2019

Animal cells have evolved dedicated molecular systems for sensing and delivering a coordinated response to viral threats. Our understanding of these pathways is almost entirely defined by studies in humans or model organisms like mice, fruit flies an...

  • Article
  • Open Access
12 Citations
5,219 Views
14 Pages

A Novel RNA Virus Related to Sobemoviruses Confers Hypovirulence on the Phytopathogenic Fungus Sclerotinia sclerotiorum

  • Ayesha Azhar,
  • Fan Mu,
  • Huang Huang,
  • Jiasen Cheng,
  • Yanping Fu,
  • Muhammad Rizwan Hamid,
  • Daohong Jiang and
  • Jiatao Xie

16 August 2019

Infection by diverse mycoviruses is a common phenomenon in Sclerotinia sclerotiorum. In this study, the full genome of a single-stranded RNA mycovirus, tentatively named Hubei sclerotinia RNA virus 1 (HuSRV1), was determined in the hypovirulent strai...

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Viruses - ISSN 1999-4915