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Viruses, Volume 17, Issue 10

October 2025 - 118 articles

Cover Story: This study presents data on the characterization of extracellular vesicles (EVs) released by human adenovirus type 4-infected lung epithelial cells at the pre-lytic stage of infection. CD9/CD63/CD81-positive EVs purified from infected cell supernatants displayed a distinct protein and small non-coding RNA profile compared to EVs from uninfected controls. Their unique cargo included viral genomic DNA, virus associated RNAs I and II and select viral proteins such as the non-structural DNA-binding protein DBP and L4-100K. Importantly, in the absence of any visible viral particles, these EV preparations were infectious, operating as vehicles for non-lytic viral spread. This interplay between adenovirus and host EV biogenesis highlights the potential role of EVs in intra-host dissemination. View this paper
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Articles (118)

  • Article
  • Open Access
454 Views
20 Pages

Cross-Species Transmission Risks of a Quail-Origin H7N9 Influenza Virus from China Between Avian and Mammalian Hosts

  • Cheng Zhang,
  • Yifei Jin,
  • Huan Cui,
  • Zhongyi Wang,
  • Zhaoliang Chen,
  • Lei Zhang,
  • Sihui Song,
  • Bing Lu and
  • Zhendong Guo

21 October 2025

The H7N9 influenza viruses, which are capable of causing severe respiratory syndrome in humans, were first discovered to infect humans in 2013 and continue to pose a persistent public health threat. Quail has been proposed as a potential intermediate...

  • Article
  • Open Access
5,491 Views
21 Pages

Baseline Dysregulation in B, T, and NK Cells in COVID-19 Predicts Increased Late Mortality but Not Long-COVID Symptoms: Results from a Single-Center Observational Study

  • Aleksandra Matyja-Bednarczyk,
  • Radosław Dziedzic,
  • Anna Drynda,
  • Ada Gradzikiewicz,
  • Monika Bociąga-Jasik,
  • Krzysztof Wójcik,
  • Sabina Lichołai,
  • Karolina Górka,
  • Natalia Celejewska-Wójcik and
  • Tomasz Stachura
  • + 5 authors

21 October 2025

The SARS-CoV-2 pandemic presents a broad clinical spectrum from asymptomatic cases to severe respiratory failure with high mortality. Severe COVID-19 is characterized by immune dysregulation, including lymphopenia and alterations in the counts of T,...

  • Article
  • Open Access
654 Views
17 Pages

21 October 2025

JC virus (JCV) replicates within the nuclei of glial cells in the human brain and causes progressive multifocal leukoencephalopathy. JCV possesses a small, circular, double-stranded DNA genome, divided into early and late protein-coding regions. The...

  • Article
  • Open Access
692 Views
14 Pages

Metatranscriptomic Analysis of Oropharyngeal Samples Reveals Common Respiratory Viruses and a Potential Interspecies Transmitted Picobirnavirus in the Wayuu Population, La Guajira, Colombia

  • Beatriz Elena De arco-Rodríguez,
  • Jhindy Tatiana Pérez-Lozada,
  • Katherine Laiton-Donato,
  • Dioselina Peláez-Carvajal,
  • Gloria Mercedes Puerto-Castro and
  • Diego Alejandro Álvarez-Díaz

21 October 2025

Acute respiratory infections and other infectious diseases causing acute febrile syndrome are major public health concerns in Colombia, particularly among vulnerable populations such as the Wayuu Indigenous community in Manaure, La Guajira. To invest...

  • Review
  • Open Access
664 Views
24 Pages

Immune Evasion by the NSs Protein of Rift Valley Fever Virus: A Viral Houdini Act

  • Kaylee Petraccione,
  • James G. Omichinski and
  • Kylene Kehn-Hall

21 October 2025

Rift Valley fever virus (RVFV) is a negative-sense arbovirus that causes several severe diseases, including hemorrhagic fever in ruminants and humans. There are currently no FDA-approved vaccines or therapeutics for RVFV. The viral nonstructural prot...

  • Systematic Review
  • Open Access
1,024 Views
30 Pages

Vertical Transmission of Hepatitis B and C—Then and Now—A Comprehensive Literature Systematic Review

  • Ruxandra Dobritoiu,
  • Daniela Pacurar,
  • Raluca Maria Vlad and
  • Doina Anca Plesca

20 October 2025

Background: According to a WHO global hepatitis report, the global prevalence of hepatitis B in 2022 was 254 million and for hepatitis C it was 50 million. The estimated number of people newly infected by viral hepatitis declined from 3 million in 20...

  • Article
  • Open Access
376 Views
20 Pages

20 October 2025

Pomme fruits are propagated vegetatively, thereby facilitating frequent viral transmission. The causative agent of apple rubbery wood disease, apple rubbery wood virus 2 (ARWV2), can infect apple and pear. The branches of ARWV2-infected, symptomatic...

  • Article
  • Open Access
539 Views
21 Pages

Reinfection Dynamics of Disease-Free Cassava Plants in Three Agroecological Regions of Côte d’Ivoire

  • John Steven S. Seka,
  • Justin S. Pita,
  • Modeste K. Kouassi,
  • William J. -L. Amoakon,
  • Bekanvié S. M. Kouakou,
  • Mariam Combala,
  • Daniel H. Otron,
  • Brice Sidoine Essis,
  • Konan Evrard B. Dibi and
  • Angela O. Eni
  • + 2 authors

20 October 2025

Cassava mosaic disease (CMD) is caused by begomoviruses and can result in yield losses of up to 90% in susceptible varieties. Using disease-free planting material from in vitro cultures is one of the most effective ways of controlling this disease. A...

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Viruses - ISSN 1999-4915