Marine Drugs, Volume 23, Issue 9

Retinoid X receptor α (RXRα) plays a vital role in multiple biological and pathological processes and represents a promising therapeutic target for anti-tumor drug design. Inspired by the marine-derived RXRα antagonist meroterpenthi...

Biological invasions threaten biodiversity worldwide. The American blue crab Callinectes sapidus Rathbun, 1896, among the Mediterranean’s most damaging invaders, takes up the challenge to transform this threat into gain. To turn its impact into...

Angiogenesis is a fundamental biological process involved in the formation of new blood vessels from the pre-existing vascular network. In addition to physiological processes, angiogenesis is also implicated in pathological conditions such as tumour...

This review examines recent advances in the extraction of valuable compounds from seaweed biomass, focusing on practical feasibility and environmental sustainability. There is a growing importance of seaweed biomass in terms of the study and acknowle...

Cardiac hypertrophy is a critical contributor to cardiac dysfunction and the development of heart failure, yet effective therapeutic strategies remain limited. Propylene glycol alginate sulfate sodium (PSS) is a marine sulfated polysaccharide drug us...

The formation of amyloid-like structures is commonly linked to neurodegenerative diseases, such as Parkinson’s and Alzheimer’s. However, proteins can form amyloid-like structures in non-pathological contexts, referred to as functional amy...

Using the one-strain-many-compounds (OSMAC) culturing approach, metabolomic studies, and bioassay-guided purification, we have isolated and characterised three new chlorinated natural products, agelolines B-D (1–3), together with two known comp...

Porphyridium purpureum can synthesize a high phycoerythrin content, which has strong potential application in nutrition, pharmaceuticals, and cosmetics. An effective culture strategy is the key to producing biomass of P. purpureum rich in phycoerythr...

Lutein, a crucial carotenoid with diverse biological roles, is in high demand in the market. Current production predominantly relies on plant extraction, which is hindered by low yield and seasonal limitations. Microalgae, such as Chlorella and Chlam...

This study investigated the occurrence, sources, and health risks of 21 per- and polyfluoroalkyl substances (PFAS) in commercially available shellfish and crustaceans from Zhejiang Province, China. Among the 306 samples analyzed, 87.9% contained at l...