Bio-Active Components from Marine Sponge

A special issue of Marine Drugs (ISSN 1660-3397). This special issue belongs to the section "Marine Chemoecology for Drug Discovery".

Deadline for manuscript submissions: 30 June 2025 | Viewed by 1436

Special Issue Editor


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Guest Editor
IRD, Univ. Brest, CNRS, Ifremer, LEMAR, F-29280 Plouzane, France
Interests: marine invertebrates; natural product extraction; natural product isolation; bioactive compounds; chemotaxonomy; quorum sensing; anticancer and anti-infective agents; scientific database
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Special Issue Information

Dear Colleagues,

This Special Issue focuses on bioactive components derived from marine sponges and offers researchers the opportunity to publish original work on various topics, including natural products derived from sponges and their associated microorganisms; the presentation of biological activities in many domains, whether for health-related, environmental, or biotechnological applications; and chemical ecology studies. Sustainable production via chemical synthesis and bioproduction through the culture of these bioactive specialized marine metabolites are of great interest in the context of blue chemistry. In this Special Issue, we welcome papers on all of these chemical, biological, and ecological aspects.

Dr. Sylvain Petek
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Marine Drugs is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • sponges
  • isolation
  • synthesis
  • bioactivity
  • anti-cancer
  • anti-infective
  • human health
  • animal health
  • eco-friendly solution
  • chemical ecology

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Published Papers (1 paper)

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Review

50 pages, 6603 KiB  
Review
Bioactive Terpenes from Marine Sponges and Their Associated Organisms
by Yuan Yuan, Yu Lei, Muwu Xu, Bingxin Zhao and Shihai Xu
Mar. Drugs 2025, 23(3), 96; https://doi.org/10.3390/md23030096 - 21 Feb 2025
Viewed by 1293
Abstract
In recent years, marine natural products have continued to serve as a pivotal resource for novel drug discovery. Globally, the number of studies focusing on Porifera has been on the rise, underscoring their considerable importance and research value. Marine sponges are prolific producers [...] Read more.
In recent years, marine natural products have continued to serve as a pivotal resource for novel drug discovery. Globally, the number of studies focusing on Porifera has been on the rise, underscoring their considerable importance and research value. Marine sponges are prolific producers of a vast array of bioactive compounds, including terpenes, alkaloids, peptides, and numerous secondary metabolites. Over the past fifteen years, a substantial number of sponge-derived terpenes have been identified, exhibiting extensive structural diversity and notable biological activities. These terpenes have been isolated from marine sponges or their associated symbiotic microorganisms, with several demonstrating multifaceted biological activities, such as anti-inflammatory, antibacterial, cytotoxic, anticancer, and antioxidant properties. In this review, we summarize 997 novel terpene metabolites, detailing their structures, sources, and activities, from January 2009 to December 2024. The structural features and structure-activity relationship (SAR) of different types of terpenes are broadly analyzed and summarized. This systematic and comprehensive review will contribute to the summary of and speculation on the taxonomy, activity profiles, and SAR of terpenes and the development of sponge-derived terpenes as potential lead drugs. Full article
(This article belongs to the Special Issue Bio-Active Components from Marine Sponge)
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