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Molecules, Volume 26, Issue 3

February-1 2021 - 256 articles

Cover Story: Nitro-substituted π-electronic molecules are fascinating because of their unique electronic and optical properties. In this study, mono- and dinitro-substituted dipyrrolyldiketone BF2 complexes were synthesized in order to investigate their electronic properties and anion-binding abilities. The obtained nitro-substituted derivatives showed solvent-dependent UV/Vis and fluorescence spectra, suggesting intramolecular charge transfer. They exhibited high anion-binding affinities due to the easily pyrrole-inverted conformations and polarized pyrrole NH sites upon the introduction of electron-withdrawing moieties. View this paper.
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Articles (256)

  • Article
  • Open Access
25 Citations
5,367 Views
28 Pages

Nuclear Magnetic Resonance Metabolomics Approach for the Analysis of Major Legume Sprouts Coupled to Chemometrics

  • Mohamed A. Farag,
  • Mohamed G. Sharaf El-Din,
  • Mohamed A. Selim,
  • Asmaa I. Owis,
  • Sameh F. Abouzid,
  • Andrea Porzel,
  • Ludger A. Wessjohann and
  • Asmaa Otify

2 February 2021

Legume sprouts are a fresh nutritive source of phytochemicals of increasing attention worldwide owing to their many health benefits. Nuclear magnetic resonance (NMR) was utilized for the metabolite fingerprinting of 4 major legume sprouts, belonging...

  • Communication
  • Open Access
8 Citations
4,246 Views
12 Pages

Microfluidic Preparation of 89Zr-Radiolabelled Proteins by Flow Photochemistry

  • Daniel F. Earley,
  • Amaury Guillou,
  • Dion van der Born,
  • Alex J. Poot and
  • Jason P. Holland

2 February 2021

89Zr-radiolabelled proteins functionalised with desferrioxamine B are a cornerstone of diagnostic positron emission tomography. In the clinical setting, 89Zr-labelled proteins are produced manually. Here, we explore the potential of using a microflui...

  • Article
  • Open Access
13 Citations
5,755 Views
39 Pages

In Silico Studies of Lamiaceae Diterpenes with Bioinsecticide Potential against Aphis gossypii and Drosophila melanogaster

  • Gabriela Cristina Soares Rodrigues,
  • Mayara dos Santos Maia,
  • Andreza Barbosa Silva Cavalcanti,
  • Natália Ferreira de Sousa,
  • Marcus Tullius Scotti and
  • Luciana Scotti

2 February 2021

Background: The growing demand for agricultural products has led to the misuse/overuse of insecticides; resulting in the use of higher concentrations and the need for ever more toxic products. Ecologically, bioinsecticides are considered better and s...

  • Article
  • Open Access
29 Citations
5,934 Views
13 Pages

2 February 2021

Soil-borne diseases and plant rhizosphere nematode have caused many crop yield losses. Increased environmental awareness is leading to more restrictions on the use of certain fumigants and root irrigation methods due to their impact on human health a...

  • Review
  • Open Access
15 Citations
7,576 Views
56 Pages

2 February 2021

The title alkaloids, often referred to collectively as crinines, are a prominent group of structurally distinct natural products with additional members being reported on a regular basis. As such, and because of their often notable biological propert...

  • Feature Paper
  • Article
  • Open Access
7 Citations
3,909 Views
17 Pages

Sulfonate-Conjugated Polyelectrolytes as Anode Interfacial Layers in Inverted Organic Solar Cells

  • Elisa Lassi,
  • Benedetta Maria Squeo,
  • Roberto Sorrentino,
  • Guido Scavia,
  • Simona Mrakic-Sposta,
  • Maristella Gussoni,
  • Barbara Vercelli,
  • Francesco Galeotti,
  • Mariacecilia Pasini and
  • Silvia Luzzati

2 February 2021

Conjugated polymers with ionic pendant groups (CPEs) are receiving increasing attention as solution-processed interfacial materials for organic solar cells (OSCs). Various anionic CPEs have been successfully used, on top of ITO (Indium Tin Oxide) ele...

  • Article
  • Open Access
24 Citations
4,881 Views
23 Pages

NMR and LC-MS-Based Metabolomics to Study Osmotic Stress in Lignan-Deficient Flax

  • Kamar Hamade,
  • Ophélie Fliniaux,
  • Jean-Xavier Fontaine,
  • Roland Molinié,
  • Elvis Otogo Nnang,
  • Solène Bassard,
  • Stéphanie Guénin,
  • Laurent Gutierrez,
  • Eric Lainé and
  • Christophe Hano
  • + 4 authors

2 February 2021

Lignans, phenolic plant secondary metabolites, are derived from the phenylpropanoid biosynthetic pathway. Although, being investigated for their health benefits in terms of antioxidant, antitumor, anti-inflammatory and antiviral properties, the role...

  • Article
  • Open Access
35 Citations
5,939 Views
21 Pages

Phytochemistry, Bioactivities, Pharmacokinetics and Toxicity Prediction of Selaginella repanda with Its Anticancer Potential against Human Lung, Breast and Colorectal Carcinoma Cell Lines

  • Mohd Adnan,
  • Arif Jamal Siddiqui,
  • Walid Sabri Hamadou,
  • Mitesh Patel,
  • Syed Amir Ashraf,
  • Arshad Jamal,
  • Amir Mahgoub Awadelkareem,
  • Manojkumar Sachidanandan,
  • Mejdi Snoussi and
  • Vincenzo De Feo

2 February 2021

In this study, we investigated the bioactive potential (antibacterial and antioxidant), anticancer activity and detailed phytochemical analysis of Selaginellarepanda (S. repanda) ethanolic crude extract for the very first time using different in vitr...

  • Article
  • Open Access
5 Citations
6,429 Views
14 Pages

New Pharmaceutical Salts of Trazodone

  • Jolanta Jaśkowska,
  • Przemysław Zaręba,
  • Anna Drabczyk,
  • Agnieszka Kozak,
  • Izabela D. Madura,
  • Zbigniew Majka and
  • Edyta Pindelska

2 February 2021

New pharmaceutically acceptable salts of trazodone (trazodone hydrogen bromide and trazodone 1-hydroxy-2-naphthonic acid) for the treatment of central nervous system disorders are synthesized and described. Although trazodone salts are poorly crystal...

  • Article
  • Open Access
14 Citations
4,469 Views
15 Pages

The Influence of Hydrolytic Enzymes on Tannin Adsorption-Desorption onto Grape Cell Walls in a Wine-Like Matrix

  • Andrea Osete-Alcaraz,
  • Encarna Gómez-Plaza,
  • Pilar Martínez-Pérez,
  • Florent Weiller,
  • Julia Schückel,
  • William G.T. Willats,
  • John P. Moore,
  • José M. Ros-García and
  • Ana B. Bautista-Ortín

2 February 2021

This study evaluates the capacity of four hydrolytic enzymes to limit the interactions between grape cell-walls and tannins and/or to favor tannin desorption. Adsorption and desorption tests were conducted by mixing a commercial seed tannin with puri...

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Molecules - ISSN 1420-3049