We have come to a point where the field of fan studies must acknowledge darker, more pathologized and potentially more sinister forms of fandom than we have heretofore. Serial killer fandom is, simultaneously, one of the most visible and least-academ...
We study statistical aspects of the case of the British nurse Ben Geen, convicted of 2 counts of murder and 15 of grievous bodily harm following events at Horton General Hospital (in the town of Banbury, Oxfordshire, UK) during December 2013–Fe...
“Bluebeard” (ATU 321: Maiden-Killer), a fairy tale about a wealthy noble man and serial killer, is the most gruesome of Charles Perrault’s fairy tales. Bluebeard epitomizes evil and horror. In Perrault’s tale, Bluebeard’...
28 April 2022
Serial murder is a specific type of violent crime that falls into the crime category of multicide. According to the nomenclature of the Federal Bureau of Investigation’s Violent Crime Classification Manual and Academic Researchers for the Class...
NK cell ADCC supports monoclonal antibody anti-tumor therapies. We investigated serial ADCC and whether it could be predicted by NK phenotypes, including expression of CD16A, CD2 and perforin. CD16A, the NK receptor for antibodies, has AA158 valine o...
In the winter of 1991, the frenzied scandal around Bret Easton Ellis’s serial killer smash American Psycho overshadowed another, no less serious literary controversy. Published less than two months after Ellis’s blockbuster, Dennis Cooper...
Tumor cells rely heavily on glycolysis to meet their high metabolic demands. While this results in nutrient deprivation within the tumor microenvironment and has negative effects on infiltrating immune cells such as natural killer (NK) cells, it also...
Sharks are among the most endangered nonhuman animals on the planet because of industrial fishing, the shark meat and fin trade, expanding recreational fishing, and other anthropogenic causes. White sharks (Carcharodon carcharias), the most visible i...
Hundreds of theories exist concerning the identity of “Jack the Ripper”. His propensity for anatomical dissection with a knife—and in particular the rapid location and removal of specific organs—led some to speculate that he must have been surgically...
Background/Objectives: Overkill is generally defined as violence demonstrably exceeding the force required to cause death, often involving a disproportionate number of inflicted injuries. Typically linked to specific mental states, this phenomenon ca...
This exploratory study analyzed how three serial killers (i.e., Bundy, Gacy, and Dahmer) potentially rationalized and justified their murders by applying techniques of neutralization. This paper discusses how the use of these neutralizations also fun...
This article reflects on the current paucity of academic research into the Whitechapel Murders of 1888. Notably it suggests that there has been a tendency for historians of crime in particular to ignore the case and it argues that this has created an...
This article considers the formal and critical consequences of organizing an aesthetic corpus around the philosophical concept of the fragment via a reading of Aryan Kaganof’s “Ten Monologues from the Lives of the Serial Killers” (1...
Tumor cells often have very high energy demands. Inhibition of glucose uptake is therefore a possible approach to limit the proliferation and survival of transformed cells. However, immune cells also require energy to initiate and to maintain anti-tu...
The prognosis of multiple myeloma (MM) has drastically improved owing to the development of new drugs, such as proteasome inhibitors and immunomodulatory drugs. Nevertheless, MM is an extremely challenging disease, and many patients are still refract...
CD8+ T lymphocytes (CTLs) act as serial killers of infected or malignant cells by releasing large amounts of interferon-gamma (IFNγ) and granzymes. Although IFNγ is a pleiotropic cytokine with diverse immunomodulatory functions, its preci...
Glypican-3 (GPC3) is an oncofetal antigen that is highly expressed in multiple solid tumors, including hepatocellular carcinoma, and is barely expressed in adult normal tissues except the placenta. NKp46 activation receptor is expressed in all-natura...
African swine fever virus (ASFV) is an important transboundary animal pathogen with significant impacts on the global swine industry. Overwhelming proinflammatory responses are a major virulence mechanism for ASFV, but the dynamics of these changes d...
P. falciparum malaria continues as the serial killer of over a million lives yearly, mainly for children in sub-Saharan Africa. For severe malaria, we are still on the quest for a prognostic marker of fatal outcome. We analysed the association betwee...
Patients with B-cell non-Hodgkin’s lymphoma (B-NHL) who fail to respond to first-line treatment regimens or develop resistance, exhibit poor prognosis. This signifies the need to develop alternative treatment strategies. CD19-chimeric antigen r...
Background: Despite recent advances and refinements in perioperative management of kidney transplantation (KT), early renal graft injury (eRGI) remains a critical problem with serious impairment of graft function as well as short- and long-term outco...